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Nuclear PTEN Controls DNA Repair and Sensitivity to Genotoxic Stress

Science (American Association for the Advancement of Science), 2013-07, Vol.341 (6144), p.395-399

2013

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SHP2 is required for BCR-ABL1-induced hematologic neoplasia

Leukemia, 2018-01, Vol.32 (1), p.203-213

2018

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T cell protein tyrosine phosphatase (TCPTP) deficiency in muscle does not alter insulin signalling and glucose homeostasis in mice

Diabetologia, 2012-02, Vol.55 (2), p.468-478

2012

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Regulation of In Vitro and In Vivo Immune Functions by the Cytosolic Adaptor Protein SKAP-HOM

Molecular and Cellular Biology, 2005-09, Vol.25 (18), p.8052-8063

2005

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New Role for Shc in Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway

Molecular and Cellular Biology, 2000-10, Vol.20 (19), p.7109-7120

2000

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Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis

Nature genetics, 2000-03, Vol.24 (3), p.296-299

2000

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Distinct populations of tumor-initiating cells derived from a tumor generated by rat mammary cancer stem cells

Proceedings of the National Academy of Sciences - PNAS, 2008-11, Vol.105 (44), p.16940-16945

2008

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Solubilization and Purification of Enzymatically Active Glutathione S-Transferase (pGEX) Fusion Proteins

Analytical biochemistry, 1993-04, Vol.210 (1), p.179-187

1993

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Identification of a Human src Homology 2-Containing Protein-Tyrosine-Phosphatase: A Putative Homolog of Drosophila Corkscrew

Proceedings of the National Academy of Sciences - PNAS, 1992-12, Vol.89 (23), p.11239-11243

1992

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Differential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1

Molecular and Cellular Biology, 1995-12, Vol.15 (12), p.7050-7058

1995

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Role of the tyrosine phosphatase SHP-1 in K562 cell differentiation

Leukemia, 2001-09, Vol.15 (9), p.1424-1432

2001

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New Insights into Tumor Suppression: PTEN Suppresses Tumor Formation by Restraining the Phosphoinositide 3-kinase/AKT Pathway

Proceedings of the National Academy of Sciences - PNAS, 1999-04, Vol.96 (8), p.4240-4245

1999

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Isolation of a src Homology 2-Containing Tyrosine Phosphatase

Proceedings of the National Academy of Sciences - PNAS, 1992-02, Vol.89 (3), p.1123-1127

1992

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Tyrosyl Phosphorylation of Shp2 Is Required for Normal ERK Activation in Response to Some, but Not All, Growth Factors

The Journal of biological chemistry, 2003-10, Vol.278 (43), p.41677-41684

2003

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Combinatorial control of the specificity of protein tyrosine phosphatases

Current Opinion in Cell Biology, 2001-04, Vol.13 (2), p.182-195

2001

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Shp2 Regulates Src Family Kinase Activity and Ras/Erk Activation by Controlling Csk Recruitment

Molecular cell, 2004-02, Vol.13 (3), p.341-355

2004

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Activation of the SH2-containing protein tyrosine phosphatase, SH-PTP2, by phosphotyrosine-containing peptides derived from insulin receptor substrate-1

The Journal of biological chemistry, 1994-05, Vol.269 (18), p.13614-13622

1994

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Protein-Tyrosine-Phosphatase SHPTP2 Couples Platelet-Derived Growth Factor Receptor β to Ras

Proceedings of the National Academy of Sciences - PNAS, 1994-07, Vol.91 (15), p.7335-7339

1994

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STAT3 signalling is required for leptin regulation of energy balance but not reproduction

Nature (London), 2003-02, Vol.421 (6925), p.856-859

2003

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PTP1B Regulates Leptin Signal Transduction In Vivo

Developmental cell, 2002-04, Vol.2 (4), p.489-495

2002

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Regulation of colony-stimulating factor 1 receptor signaling by the SH2 domain-containing tyrosine phosphatase SHPTP1

Molecular and Cellular Biology, 1996-07, Vol.16 (7), p.3685-3697

1996

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A Family of Transmembrane Proteins with Homology to the MET-Hepatocyte Growth Factor Receptor

Proceedings of the National Academy of Sciences - PNAS, 1996-01, Vol.93 (2), p.674-678

1996

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Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 ( PTPN11) mutations

Cancer cell, 2005-02, Vol.7 (2), p.179-191

2005

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Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21

Nature (London), 1992-07, Vol.358 (6384), p.351-354

1992

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Increased Energy Expenditure, Decreased Adiposity, and Tissue-Specific Insulin Sensitivity in Protein-Tyrosine Phosphatase 1B-Deficient Mice

Molecular and Cellular Biology, 2000-08, Vol.20 (15), p.5479-5489

2000

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Nuclear PTEN Controls DNA Repair and Sensitivity to Genotoxic Stress

SHP2 is required for BCR-ABL1-induced hematologic neoplasia

T cell protein tyrosine phosphatase (TCPTP) deficiency in muscle does not alter insulin signalling and glucose homeostasis in mice

Regulation of In Vitro and In Vivo Immune Functions by the Cytosolic Adaptor Protein SKAP-HOM

New Role for Shc in Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway

Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis

Distinct populations of tumor-initiating cells derived from a tumor generated by rat mammary cancer stem cells

Solubilization and Purification of Enzymatically Active Glutathione S-Transferase (pGEX) Fusion Proteins

Identification of a Human src Homology 2-Containing Protein-Tyrosine-Phosphatase: A Putative Homolog of Drosophila Corkscrew

Differential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1

Role of the tyrosine phosphatase SHP-1 in K562 cell differentiation

New Insights into Tumor Suppression: PTEN Suppresses Tumor Formation by Restraining the Phosphoinositide 3-kinase/AKT Pathway

Isolation of a src Homology 2-Containing Tyrosine Phosphatase

Tyrosyl Phosphorylation of Shp2 Is Required for Normal ERK Activation in Response to Some, but Not All, Growth Factors

Combinatorial control of the specificity of protein tyrosine phosphatases

Shp2 Regulates Src Family Kinase Activity and Ras/Erk Activation by Controlling Csk Recruitment

Activation of the SH2-containing protein tyrosine phosphatase, SH-PTP2, by phosphotyrosine-containing peptides derived from insulin receptor substrate-1

Protein-Tyrosine-Phosphatase SHPTP2 Couples Platelet-Derived Growth Factor Receptor β to Ras

STAT3 signalling is required for leptin regulation of energy balance but not reproduction

PTP1B Regulates Leptin Signal Transduction In Vivo

Regulation of colony-stimulating factor 1 receptor signaling by the SH2 domain-containing tyrosine phosphatase SHPTP1

A Family of Transmembrane Proteins with Homology to the MET-Hepatocyte Growth Factor Receptor

Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 ( PTPN11) mutations

Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21

Increased Energy Expenditure, Decreased Adiposity, and Tissue-Specific Insulin Sensitivity in Protein-Tyrosine Phosphatase 1B-Deficient Mice

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