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Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response

Cell stem cell, 2019-04, Vol.24 (4), p.551-565.e8

2019

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Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression

Cell, 2017-09, Vol.170 (6), p.1079-1095.e20

2017

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Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation

Cancer cell, 2011-07, Vol.20 (1), p.11-24

2011

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TET1 is a tumor suppressor of hematopoietic malignancy

Nature immunology, 2015-06, Vol.16 (6), p.653

2015

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Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo

The Journal of experimental medicine, 2013-11, Vol.210 (12), p.2641-2659

2013

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Notch pathway activation targets AML-initiating cell homeostasis and differentiation

The Journal of experimental medicine, 2013-02, Vol.210 (2), p.301-319

2013

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NF-κB Regulates Spatial Memory Formation and Synaptic Plasticity through Protein Kinase A/CREB Signaling

Molecular and Cellular Biology, 2006-04, Vol.26 (8), p.2936-2946

2006

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The Notch Ligand Delta1 Is Sequentially Cleaved by an ADAM Protease and γ-Secretase

Proceedings of the National Academy of Sciences - PNAS, 2003-06, Vol.100 (13), p.7638-7643

2003

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Novel repertoire of tau biosensors to monitor pathological tau transformation and seeding activity in living cells

eLife, 2023-03, Vol.12

2023

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The orphan GPR50 receptor promotes constitutive TGFβ receptor signaling and protects against cancer development

Nature communications, 2018-03, Vol.9 (1), p.1216-15, Article 1216

2018

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Ectodermal influx and cell hypertrophy provide early growth for all murine mammary rudiments, and are differentially regulated among them by Gli3

PloS one, 2011-10, Vol.6 (10), p.e26242-e26242

2011

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Necdin, a p53 target gene, regulates the quiescence and response to genotoxic stress of hematopoietic stem/progenitor cells

Blood, 2012-08, Vol.120 (8), p.1601-1612

2012

Volltextzugriff (PDF)

Pharmacological evidence for transactivation within melatonin MT2 and serotonin 5‐HT2C receptor heteromers in mouse brain

The FASEB journal, 2021-01, Vol.35 (1), p.e21161-n/a

2021

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Role of FGF10/FGFR2b signaling during mammary gland development in the mouse embryo

Development (Cambridge), 2002-01, Vol.129 (1), p.53-60

2002

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intracellular region of Notch ligands Dll1 and Dll3 regulates their trafficking and signaling activity

Proceedings of the National Academy of Sciences - PNAS, 2008-08, Vol.105 (32), p.11212-11217

2008

Volltextzugriff (PDF)

Pharmacological evidence for transactivation within melatonin MT 2 and serotonin 5-HT 2C receptor heteromers in mouse brain

The FASEB journal, 2021-01, Vol.35 (1), p.e21161

2021

Volltextzugriff (PDF)

A glycosphingolipid binding domain controls trafficking and activity of the mammalian notch ligand delta-like 1

PloS one, 2013-09, Vol.8 (9), p.e74392-e74392

2013

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NF-κB Activation during Acute Helicobacter pylori Infection in Mice

Infection and Immunity, 2008-02, Vol.76 (2), p.551-561

2008

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Generation of a novel, multi-stage, progressive, and transplantable model of plasma cell neoplasms

Scientific reports, 2016-03, Vol.6 (1), p.22760-22760, Article 22760

2016

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The Notch Ligand Delta1 Recruits Dlg1 at Cell-Cell Contacts and Regulates Cell Migration[boxs]

The Journal of biological chemistry, 2004-12, Vol.279 (53), p.55818-55826

2004

Volltextzugriff (PDF)

The Methylcytosine Dioxygenase Tet2 Promotes DNA Demethylation and Activation of Cytokine Gene Expression in T Cells

Immunity (Cambridge, Mass.), 2015-04, Vol.42 (4), p.613-626

2015

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Forebrain-Specific Neuronal Inhibition of Nuclear Factor-κB Activity Leads to Loss of Neuroprotection

The Journal of neuroscience, 2003-10, Vol.23 (28), p.9403-9408

2003

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Regulation of c-Myc Ubiquitination Controls Chronic Myelogenous Leukemia Initiation and Progression

Cancer cell, 2013-03, Vol.23 (3), p.362-375

2013

Volltextzugriff (PDF)

Therapeutic Targeting of the Cyclin D3:CDK4/6 Complex in T Cell Leukemia

Cancer cell, 2012-10, Vol.22 (4), p.452-465

2012

Volltextzugriff (PDF)

The intracellular region of Notch ligands DII1 and DII3 regulates their trafficking and signaling activity

Proceedings of the National Academy of Sciences - PNAS, 2008-08, Vol.105 (32), p.11212

2008

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Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response

Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression

Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation

TET1 is a tumor suppressor of hematopoietic malignancy

Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo

Notch pathway activation targets AML-initiating cell homeostasis and differentiation

NF-κB Regulates Spatial Memory Formation and Synaptic Plasticity through Protein Kinase A/CREB Signaling

The Notch Ligand Delta1 Is Sequentially Cleaved by an ADAM Protease and γ-Secretase

Novel repertoire of tau biosensors to monitor pathological tau transformation and seeding activity in living cells

The orphan GPR50 receptor promotes constitutive TGFβ receptor signaling and protects against cancer development

Ectodermal influx and cell hypertrophy provide early growth for all murine mammary rudiments, and are differentially regulated among them by Gli3

Necdin, a p53 target gene, regulates the quiescence and response to genotoxic stress of hematopoietic stem/progenitor cells

Pharmacological evidence for transactivation within melatonin MT2 and serotonin 5‐HT2C receptor heteromers in mouse brain

Role of FGF10/FGFR2b signaling during mammary gland development in the mouse embryo

intracellular region of Notch ligands Dll1 and Dll3 regulates their trafficking and signaling activity

Pharmacological evidence for transactivation within melatonin MT 2 and serotonin 5-HT 2C receptor heteromers in mouse brain

A glycosphingolipid binding domain controls trafficking and activity of the mammalian notch ligand delta-like 1

NF-κB Activation during Acute Helicobacter pylori Infection in Mice

Generation of a novel, multi-stage, progressive, and transplantable model of plasma cell neoplasms

The Notch Ligand Delta1 Recruits Dlg1 at Cell-Cell Contacts and Regulates Cell Migration[boxs]

The Methylcytosine Dioxygenase Tet2 Promotes DNA Demethylation and Activation of Cytokine Gene Expression in T Cells

Forebrain-Specific Neuronal Inhibition of Nuclear Factor-κB Activity Leads to Loss of Neuroprotection

Regulation of c-Myc Ubiquitination Controls Chronic Myelogenous Leukemia Initiation and Progression

Therapeutic Targeting of the Cyclin D3:CDK4/6 Complex in T Cell Leukemia

The intracellular region of Notch ligands DII1 and DII3 regulates their trafficking and signaling activity

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