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Balancing lysosome abundance in health and disease

Nature cell biology, 2023-09, Vol.25 (9), p.1254-1264

2023

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mTORC1 Promotes Metabolic Reprogramming by the Suppression of GSK3-Dependent Foxk1 Phosphorylation

Molecular cell, 2018-06, Vol.70 (5), p.949-960.e4

2018

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Rap1-GTPases control mTORC1 activity by coordinating lysosome organization with amino acid availability

Nature communications, 2020-03, Vol.11 (1), p.1416-1416, Article 1416

2020

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ERK2 regulates epithelial-to-mesenchymal plasticity through DOCK10-dependent Rac1/FoxO1 activation

Proceedings of the National Academy of Sciences - PNAS, 2019-02, Vol.116 (8), p.2967-2976

2019

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Regulation of GSK3 cellular location by FRAT modulates mTORC1-dependent cell growth and sensitivity to rapamycin

Proceedings of the National Academy of Sciences - PNAS, 2019-09, Vol.116 (39), p.19523-19529

2019

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Checkpoints in a yeast differentiation pathway coordinate signaling during hyperosmotic stress

PLoS genetics, 2012-01, Vol.8 (1), p.e1002437-e1002437

2012

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Regulation of Cell Signaling Dynamics by the Protein Kinase-Scaffold Ste5

Molecular cell, 2008-06, Vol.30 (5), p.649-656

2008

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Molecular Genetic Anatomy of Inter- and Intraserotype Variation in the Human Bacterial Pathogen Group A Streptococcus

Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (18), p.7059-7064

2006

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Nutrient signaling: Starvation flips a phosphoinositide switch on lysosomal catabolism

Current biology, 2023-12, Vol.33 (24), p.R1289-R1291

2023

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Genome Sequence of a Serotype M28 Strain of Group A Streptococcus: Potential New Insights into Puerperal Sepsis and Bacterial Disease Specificity

The Journal of infectious diseases, 2005-09, Vol.192 (5), p.760-770

2005

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Emergence of a bacterial clone with enhanced virulence by acquisition of a phage encoding a secreted phospholipase A2

Proceedings of the National Academy of Sciences - PNAS, 2006-10, Vol.103 (43), p.16009-16014

2006

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Positive roles for negative regulators in the mating response of yeast

Molecular systems biology, 2012-06, Vol.8 (1), p.586-n/a

2012

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Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase

Proceedings of the National Academy of Sciences - PNAS, 2024-05, Vol.121 (21), p.e2403685121

2024

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Signal inhibition by a dynamically regulated pool of monophosphorylated MAPK

Molecular biology of the cell, 2015-09, Vol.26 (18), p.3359-3371

2015

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Proper Protein Glycosylation Promotes Mitogen-Activated Protein Kinase Signal Fidelity

Biochemistry (Easton), 2013-01, Vol.52 (1), p.115-124

2013

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Combined computational and experimental analysis reveals mitogen-activated protein kinase-mediated feedback phosphorylation as a mechanism for signaling specificity

Molecular biology of the cell, 2012-10, Vol.23 (19), p.3899-3910

2012

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Analysis of the aerobactin and ferric hydroxamate uptake systems of Yersinia pestis

Microbiology (Society for General Microbiology), 2007-07, Vol.153 (Pt 7), p.2332-2341

2007

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Crystal Structure of Group A Streptococcus Mac-1: Insight into Dimer-Mediated Specificity for Recognition of Human IgG

Structure (London), 2006-02, Vol.14 (2), p.225-235

2006

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Analysis of a Novel Prophage-encoded Group A Streptococcus Extracellular Phospholipase A2

The Journal of biological chemistry, 2004-10, Vol.279 (44), p.45909-45918

2004

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Emergence of a Bacterial Clone with Enhanced Virulence by Acquisition of a Phage Encoding a Secreted Phospholipase A

Proceedings of the National Academy of Sciences - PNAS, 2006-10, Vol.103 (43), p.16009-16014

2006

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Proper protein glycosylation promotes MAPK signal fidelity

Biochemistry (Easton), 2012-12, Vol.52 (1), p.115-124

2012

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Cells Prioritize Responses When Faced With a Decision Between an Environmental Stress and a Developmental Cue

The FASEB journal, 2010-04, Vol.24 (S1), p.lb171-lb171

2010

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Emergence of a bacterial clone with enhanced virulence by acquisition of a phage encoding a secreted phospholipase A^sub 2

Proceedings of the National Academy of Sciences - PNAS, 2006-10, Vol.103 (43), p.16009

2006

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Analysis of a novel prophage-encoded group A Streptococcus extracellular phospholipase A(2)

The Journal of biological chemistry, 2004-10, Vol.279 (44), p.45909

2004

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Emergence of a bacterial clone with enhanced virulence by acquisition of a phage encoding a secreted phospholipase A 2

Proceedings of the National Academy of Sciences - PNAS, 2006-10, Vol.103 (43), p.16009-16014

2006

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Balancing lysosome abundance in health and disease

mTORC1 Promotes Metabolic Reprogramming by the Suppression of GSK3-Dependent Foxk1 Phosphorylation

Rap1-GTPases control mTORC1 activity by coordinating lysosome organization with amino acid availability

ERK2 regulates epithelial-to-mesenchymal plasticity through DOCK10-dependent Rac1/FoxO1 activation

Regulation of GSK3 cellular location by FRAT modulates mTORC1-dependent cell growth and sensitivity to rapamycin

Checkpoints in a yeast differentiation pathway coordinate signaling during hyperosmotic stress

Regulation of Cell Signaling Dynamics by the Protein Kinase-Scaffold Ste5

Molecular Genetic Anatomy of Inter- and Intraserotype Variation in the Human Bacterial Pathogen Group A Streptococcus

Nutrient signaling: Starvation flips a phosphoinositide switch on lysosomal catabolism

Genome Sequence of a Serotype M28 Strain of Group A Streptococcus: Potential New Insights into Puerperal Sepsis and Bacterial Disease Specificity

Emergence of a bacterial clone with enhanced virulence by acquisition of a phage encoding a secreted phospholipase A2

Positive roles for negative regulators in the mating response of yeast

Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase

Signal inhibition by a dynamically regulated pool of monophosphorylated MAPK

Proper Protein Glycosylation Promotes Mitogen-Activated Protein Kinase Signal Fidelity

Combined computational and experimental analysis reveals mitogen-activated protein kinase-mediated feedback phosphorylation as a mechanism for signaling specificity

Analysis of the aerobactin and ferric hydroxamate uptake systems of Yersinia pestis

Crystal Structure of Group A Streptococcus Mac-1: Insight into Dimer-Mediated Specificity for Recognition of Human IgG

Analysis of a Novel Prophage-encoded Group A Streptococcus Extracellular Phospholipase A2

Emergence of a Bacterial Clone with Enhanced Virulence by Acquisition of a Phage Encoding a Secreted Phospholipase A

Proper protein glycosylation promotes MAPK signal fidelity

Cells Prioritize Responses When Faced With a Decision Between an Environmental Stress and a Developmental Cue

Emergence of a bacterial clone with enhanced virulence by acquisition of a phage encoding a secreted phospholipase A^sub 2

Analysis of a novel prophage-encoded group A Streptococcus extracellular phospholipase A(2)

Emergence of a bacterial clone with enhanced virulence by acquisition of a phage encoding a secreted phospholipase A 2

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