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AT-0174, a novel dual IDO1/TDO2 enzyme inhibitor, synergises with temozolomide to improve survival in an orthotopic mouse model of glioblastoma

BMC cancer, 2024-07, Vol.24 (1), p.1-15, Article 889

2024

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Fucoidan Independently Enhances Activity in Human Immune Cells and Has a Cytostatic Effect on Prostate Cancer Cells in the Presence of Nivolumab

Marine drugs, 2021-12, Vol.20 (1), p.12

2021

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IDO Targeting in Sarcoma: Biological and Clinical Implications

Frontiers in immunology, 2020-03, Vol.11, p.274-274

2020

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Progressive Parkinsonism by acute dysfunction of excitatory amino acid transporters in the rat substantia nigra

Neurobiology of disease, 2014-05, Vol.65, p.69-81

2014

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817 DT095895, a selective EP4 receptor antagonist with monotherapy efficacy in syngeneic mouse model(s) and best-in-class properties

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A865-A865

2020

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Preferential vulnerability of mesencephalic dopamine neurons to glutamate transporter dysfunction

Journal of neurochemistry, 2008-04, Vol.105 (2), p.484-496

2008

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Abstract 3938: Anti-angiogenic therapy combination with hypoxia-regulating agent leads to improved tumor regression in a murine model or renal carcinoma

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.3938-3938

2020

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Abstract 4993: The Kynurenine Pathway as a possible resistance mechanism to immunotherapy in sarcomas

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.4993-4993

2019

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Abstract 6658: Deciphering anti-PDL1 effect in a syngeneic mouse model of sarcoma

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.6658-6658

2020

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Upregulation of Indoleamine 2,3-Dioxygenase 1 in Tumor Cells and Tertiary Lymphoid Structures is a Hallmark of Inflamed Non-Small Cell Lung Cancer

Clinical cancer research, 2023-12, Vol.29 (23), p.4883

2023

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TROP2 Is Associated with Primary Resistance to Immune Checkpoint Inhibition in Patients with Advanced Non-Small Cell Lung Cancer

Clinical cancer research, 2024-02, Vol.30 (4), p.779

2024

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Abstract 934: “GPCR-ome” modulation upon PD1 / PDL1 axis blockade

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.934-934

2020

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Impact of acetaminophen on the efficacy of immunotherapy in patients with cancer

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.12000-12000

2022

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Abstract 6697: DT095895, a selective EP4 receptor antagonist with monotherapy efficacy in syngeneic mouse model(s) and best-in-class properties

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.6697-6697

2020

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814 DT-9081, a selective EP4 receptor antagonist which synergizes with immune checkpoint inhibitors to induce complete responses in syngeneic murine cancer models

Journal for immunotherapy of cancer, 2022-11, Vol.10 (Suppl 2), p.A850-A850

2022

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Abstract 2527: Ovarian cancer ascites display altered immune environment featured by enhanced soluble factors and suppressive cellular context

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.2527-2527

2022

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Abstract 5716: Functional evidence for an immunosuppressive role of kynurenine in cancer patients

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.5716-5716

2018

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Abstract 4705: Profiling of immune cell components and soluble factors in ovarian cancer ascites highlights impaired immune environment

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.4705-4705

2023

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Abstract 4341: Indoleamine 2,3-dioxygenase 1 is highly expressed in tertiary lymphoid structures and associated with improved outcome in patients with advanced non-small cell lung cancer treated with anti-PD1/PDL1 inhibitors

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.4341-4341

2023

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Abstract 622: Development and characterization of a novel anti-PD1 resistant sarcoma mouse model

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.622-622

2022

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Abstract 1251: Low plasma Arginine level is associated with resistance to immune checkpoint blockers in patients with advanced cancer

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.1251-1251

2022

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Glutamate leakage from a compartmentalized intracellular metabolic pool and activation of the lipoxygenase pathway mediate oxidative astrocyte death by reversed glutamate transport

Glia, 2006-07, Vol.54 (1), p.47-57

2006

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Interrelationships between Prey and Predators and How Predators Choose Their Prey to Maximize Their Utility Functions

Journal of applied mathematics, 2021-02, Vol.2021, p.1-8

2021

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A Fast Algorithm for Solving a Class of the Linear Complementarity Problem in a Finite Number of Steps

Abstract and applied analysis, 2020, Vol.2020, p.1-8

2020

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AT-0174, a novel dual IDO1/TDO2 enzyme inhibitor, synergises with temozolomide to improve survival in an orthotopic mouse model of glioblastoma

Fucoidan Independently Enhances Activity in Human Immune Cells and Has a Cytostatic Effect on Prostate Cancer Cells in the Presence of Nivolumab

IDO Targeting in Sarcoma: Biological and Clinical Implications

Progressive Parkinsonism by acute dysfunction of excitatory amino acid transporters in the rat substantia nigra

817 DT095895, a selective EP4 receptor antagonist with monotherapy efficacy in syngeneic mouse model(s) and best-in-class properties

Preferential vulnerability of mesencephalic dopamine neurons to glutamate transporter dysfunction

Abstract 3938: Anti-angiogenic therapy combination with hypoxia-regulating agent leads to improved tumor regression in a murine model or renal carcinoma

Abstract 4993: The Kynurenine Pathway as a possible resistance mechanism to immunotherapy in sarcomas

Abstract 6658: Deciphering anti-PDL1 effect in a syngeneic mouse model of sarcoma

Upregulation of Indoleamine 2,3-Dioxygenase 1 in Tumor Cells and Tertiary Lymphoid Structures is a Hallmark of Inflamed Non-Small Cell Lung Cancer

TROP2 Is Associated with Primary Resistance to Immune Checkpoint Inhibition in Patients with Advanced Non-Small Cell Lung Cancer

Abstract 934: “GPCR-ome” modulation upon PD1 / PDL1 axis blockade

Impact of acetaminophen on the efficacy of immunotherapy in patients with cancer

Abstract 6697: DT095895, a selective EP4 receptor antagonist with monotherapy efficacy in syngeneic mouse model(s) and best-in-class properties

814 DT-9081, a selective EP4 receptor antagonist which synergizes with immune checkpoint inhibitors to induce complete responses in syngeneic murine cancer models

Abstract 2527: Ovarian cancer ascites display altered immune environment featured by enhanced soluble factors and suppressive cellular context

Abstract 5716: Functional evidence for an immunosuppressive role of kynurenine in cancer patients

Abstract 4705: Profiling of immune cell components and soluble factors in ovarian cancer ascites highlights impaired immune environment

Abstract 4341: Indoleamine 2,3-dioxygenase 1 is highly expressed in tertiary lymphoid structures and associated with improved outcome in patients with advanced non-small cell lung cancer treated with anti-PD1/PDL1 inhibitors

Abstract 622: Development and characterization of a novel anti-PD1 resistant sarcoma mouse model

Abstract 1251: Low plasma Arginine level is associated with resistance to immune checkpoint blockers in patients with advanced cancer

Glutamate leakage from a compartmentalized intracellular metabolic pool and activation of the lipoxygenase pathway mediate oxidative astrocyte death by reversed glutamate transport

Interrelationships between Prey and Predators and How Predators Choose Their Prey to Maximize Their Utility Functions

A Fast Algorithm for Solving a Class of the Linear Complementarity Problem in a Finite Number of Steps

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