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Regioselective Synthesis and Slow-Release Suzuki–Miyaura Cross-Coupling of MIDA Boronate-Functionalized Isoxazoles and Triazoles

Journal of organic chemistry, 2011-12, Vol.76 (24), p.10241-10248

2011

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A method for estimating the risk of drug-induced phototoxicity and its application to smoothened inhibitors

MedChemComm, 2011-10, Vol.2 (10), p.973

2011

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Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer

Journal of medicinal chemistry, 2018-04, Vol.61 (7), p.2837-2864

2018

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Discovery of an Acrylic Acid Based Tetrahydroisoquinoline as an Orally Bioavailable Selective Estrogen Receptor Degrader for ERα+ Breast Cancer

Journal of medicinal chemistry, 2017-04, Vol.60 (7), p.2790-2818

2017

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Discovery of a Brain-Penetrant ATP-Competitive Inhibitor of the Mechanistic Target of Rapamycin (mTOR) for CNS Disorders

Journal of medicinal chemistry, 2020-02, Vol.63 (3), p.1068-1083

2020

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One-Pot Reductive Amination and Suzuki–Miyaura Cross-Coupling of Formyl Aryl and Heteroaryl MIDA Boronates in Array Format

Journal of organic chemistry, 2011-06, Vol.76 (12), p.4930-4940

2011

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Discovery of 2‑Pyridylpyrimidines as the First Orally Bioavailable GPR39 Agonists

ACS medicinal chemistry letters, 2014-10, Vol.5 (10), p.1114-1118

2014

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Piperazine Sulfonamides as Potent, Selective, and Orally Available 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors with Efficacy in the Rat Cortisone-Induced Hyperinsulinemia Model

Journal of medicinal chemistry, 2008-07, Vol.51 (14), p.4068-4071

2008

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Benzenesulfonamide indole inhibitors of cytosolic phospholipase A2α : Optimization of in vitro potency and rat pharmacokinetics for oral efficacy

Bioorganic & medicinal chemistry, 2008-02, Vol.16 (3), p.1345-1358

2008

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Benzenesulfonamide indole inhibitors of cytosolic phospholipase A 2α: Optimization of in vitro potency and rat pharmacokinetics for oral efficacy

Bioorganic & medicinal chemistry, 2008, Vol.16 (3), p.1345-1358

2008

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Discovery of an Acrylic Acid Based Tetrahydroisoquinoline as an Orally Bioavailable Selective Estrogen Receptor Degrader for ERα+ Breast Cancer

Journal of medicinal chemistry, 2017-04, Vol.60 (7), p.2790-2818

2017

Volltextzugriff (PDF)

Piperazine sulfonamides as potent, selective, and orally available 11beta-hydroxysteroid dehydrogenase type 1 inhibitors with efficacy in the rat cortisone-induced hyperinsulinemia model

Journal of medicinal chemistry, 2008-07, Vol.51 (14), p.4068

2008

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Benzenesulfonamide indole inhibitors of cytosolic phospholipase A2alpha: optimization of in vitro potency and rat pharmacokinetics for oral efficacy

Bioorganic & medicinal chemistry, 2008-02, Vol.16 (3), p.1345

2008

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ChemInform Abstract: Regioselective Synthesis and Slow-Release Suzuki-Miyaura Cross-Coupling of MIDA Boronate-Functionalized Isoxazoles and Triazoles

ChemInform, 2012-04, Vol.43 (15), p.no-no

2012

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Two Phase 3 Trials of Baricitinib for Alopecia Areata

The New England journal of medicine, 2022-05, Vol.386 (18), p.1687-1699

2022

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A Randomized Evaluation of MoodFX, a Patient-Centred e-Health Tool to Support Outcome Measurement for Depression: Une évaluation randomisée de MoodFX, un outil de santé en ligne centré sur le patient pour soutenir la mesure du résultat dans la dépression

Canadian journal of psychiatry, 2024-07, Vol.69 (7), p.493-502

2024

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Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome

The New England journal of medicine, 2018-11, Vol.379 (22), p.2097-2107

2018

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American Society of Hematology 2018 guidelines for management of venous thromboembolism: prophylaxis for hospitalized and nonhospitalized medical patients

Blood advances, 2018-11, Vol.2 (22), p.3198-3225

2018

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Maternal Immunization Confers Protection to the Offspring against an Attaching and Effacing Pathogen through Delivery of IgG in Breast Milk

Cell host & microbe, 2019-02, Vol.25 (2), p.313-323.e4

2019

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Weakly haemolytic variants of Brachyspira hyodysenteriae newly emerged in Europe belong to a distinct subclade with unique genetic properties

Veterinary research (Paris), 2019-03, Vol.50 (1), p.21-13, Article 21

2019

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Crystal structure of the TSH receptor (TSHR) bound to a blocking-type TSHR autoantibody

Journal of molecular endocrinology, 2011-04, Vol.46 (2), p.81-99

2011

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Translational Research in the Time of COVID-19-Dissolving Boundaries

PLoS pathogens, 2020-09, Vol.16 (9), p.e1008898-e1008898

2020

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The Emergence of H7N7 Highly Pathogenic Avian Influenza Virus from Low Pathogenicity Avian Influenza Virus Using an in ovo Embryo Culture Model

Viruses, 2020-08, Vol.12 (9), p.920

2020

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primiReference: a reference for analysis of primary-microRNA expression in single-nucleus sequencing data

Journal of genetics and genomics, 2023-02, Vol.50 (2), p.108-121

2023

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Regioselective Synthesis and Slow-Release Suzuki–Miyaura Cross-Coupling of MIDA Boronate-Functionalized Isoxazoles and Triazoles

A method for estimating the risk of drug-induced phototoxicity and its application to smoothened inhibitors

Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer

Discovery of an Acrylic Acid Based Tetrahydroisoquinoline as an Orally Bioavailable Selective Estrogen Receptor Degrader for ERα+ Breast Cancer

Discovery of a Brain-Penetrant ATP-Competitive Inhibitor of the Mechanistic Target of Rapamycin (mTOR) for CNS Disorders

Identification of Brain-Penetrant ATP-Competitive mTOR Inhibitors for CNS Syndromes

One-Pot Reductive Amination and Suzuki–Miyaura Cross-Coupling of Formyl Aryl and Heteroaryl MIDA Boronates in Array Format

Discovery of 2‑Pyridylpyrimidines as the First Orally Bioavailable GPR39 Agonists

Piperazine Sulfonamides as Potent, Selective, and Orally Available 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors with Efficacy in the Rat Cortisone-Induced Hyperinsulinemia Model

Benzenesulfonamide indole inhibitors of cytosolic phospholipase A2α : Optimization of in vitro potency and rat pharmacokinetics for oral efficacy

Benzenesulfonamide indole inhibitors of cytosolic phospholipase A 2α: Optimization of in vitro potency and rat pharmacokinetics for oral efficacy

Discovery of an Acrylic Acid Based Tetrahydroisoquinoline as an Orally Bioavailable Selective Estrogen Receptor Degrader for ERα+ Breast Cancer

Piperazine sulfonamides as potent, selective, and orally available 11beta-hydroxysteroid dehydrogenase type 1 inhibitors with efficacy in the rat cortisone-induced hyperinsulinemia model

Benzenesulfonamide indole inhibitors of cytosolic phospholipase A2alpha: optimization of in vitro potency and rat pharmacokinetics for oral efficacy

ChemInform Abstract: Regioselective Synthesis and Slow-Release Suzuki-Miyaura Cross-Coupling of MIDA Boronate-Functionalized Isoxazoles and Triazoles

Two Phase 3 Trials of Baricitinib for Alopecia Areata

A Randomized Evaluation of MoodFX, a Patient-Centred e-Health Tool to Support Outcome Measurement for Depression: Une évaluation randomisée de MoodFX, un outil de santé en ligne centré sur le patient pour soutenir la mesure du résultat dans la dépression

Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome

American Society of Hematology 2018 guidelines for management of venous thromboembolism: prophylaxis for hospitalized and nonhospitalized medical patients

Maternal Immunization Confers Protection to the Offspring against an Attaching and Effacing Pathogen through Delivery of IgG in Breast Milk

Weakly haemolytic variants of Brachyspira hyodysenteriae newly emerged in Europe belong to a distinct subclade with unique genetic properties

Crystal structure of the TSH receptor (TSHR) bound to a blocking-type TSHR autoantibody

Translational Research in the Time of COVID-19-Dissolving Boundaries

The Emergence of H7N7 Highly Pathogenic Avian Influenza Virus from Low Pathogenicity Avian Influenza Virus Using an in ovo Embryo Culture Model

primiReference: a reference for analysis of primary-microRNA expression in single-nucleus sequencing data

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