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Biologically Active Carbazole Alkaloids from Murraya koenigii

Journal of agricultural and food chemistry, 1999-02, Vol.47 (2), p.444-447

1999

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End-processing during non-homologous end-joining: a role for exonuclease 1

Nucleic acids research, 2011-02, Vol.39 (3), p.970-978

2011

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Antitopoisomerase drug action and resistance

European journal of cancer (1990), 1996-06, Vol.32 (6), p.958-966

1996

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Mechanisms of cell killing by drugs that trap covalent complexes between DNA topoisomerases and DNA

Molecular pharmacology, 1996-11, Vol.50 (5), p.1095-1102

1996

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Aclacinomycin A stabilizes topoisomerase I covalent complexes

Cancer research (Chicago, Ill.), 1997-10, Vol.57 (20), p.4564-4569

1997

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Cytotoxicity of quinolones toward eukaryotic cells. Identification of topoisomerase. II. As the primary cellular target for the quinolone CP-115,953 in yeast

The Journal of biological chemistry, 1992-07, Vol.267 (19), p.13150-13153

1992

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Human small cell lung cancer NYH cells selected for resistance to the bisdioxopiperazine topoisomerase II catalytic inhibitor ICRF-187 demonstrate a functional R162Q mutation in the Walker A consensus ATP binding domain of the α isoform

Cancer research (Chicago, Ill.), 1999-07, Vol.59 (14), p.3442-3450

1999

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A temperature sensitive topoisomerase II allele confers temperature dependent drug resistance on amsacrine and etoposide : a genetic system for determining the targets of topoisomerase II inhibitors

Cancer research (Chicago, Ill.), 1993, Vol.53 (1), p.89-93

1993

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Amsacrine and etoposide hypersensitivity of yeast cells overexpressing DNA topoisomerase II

Cancer research (Chicago, Ill.), 1992-08, Vol.52 (16), p.4467-4472

1992

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Metabolites of Daidzein and Genistein and Their Biological Activities

Journal of natural products (Washington, D.C.), 1995-12, Vol.58 (12), p.1901-1905

1995

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Yeast recombination pathways triggered by topoisomerase II-mediated DNA breaks

Nucleic acids research, 2003-08, Vol.31 (15), p.4373-4384

2003

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Chinese hamster ovary cells resistant to the topoisomerase II catalytic inhibitor ICRF-159 : A Tyr49Phe mutation confers high-level resistance to bisdioxopiperazines

Cancer research (Chicago, Ill.), 1998-04, Vol.58 (7), p.1460-1468

1998

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Investigating the biological functions of DNA topoisomerases in eukaryotic cells

BBA - Gene Structure and Expression, 1998-10, Vol.1400 (1), p.63-81

Nitiss, John L.

1998

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DNA topoisomerase II is the molecular target of bisdioxopiperazine derivatives ICRF-159 and ICRF-193 in Saccharomyces cerevisiae

Cancer research (Chicago, Ill.), 1995-06, Vol.55 (11), p.2299-2303

1995

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A Novel Mechanism of Cell Killing by Anti-topoisomerase II Bisdioxopiperazines

The Journal of biological chemistry, 2000-01, Vol.275 (3), p.2137-2146

2000

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DNA Repair Functions That Control Sensitivity to Topoisomerase-Targeting Drugs

Eukaryotic Cell, 2004-02, Vol.3 (1), p.82-90

2004

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Functional expression of human topoisomerase IIα in yeast : mutations at amino acids 450 or 803 of topoisomerase IIα result in enzymes that can confer resistance to anti-topoisomerase II agents

Cancer research (Chicago, Ill.), 1996, Vol.56 (1), p.91-99

1996

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Using yeast to study resistance to topoisomerase II-targeting drugs

Cancer chemotherapy and pharmacology, 1994-01, Vol.34 (S1), p.S6-S13

NITISS, J. L

1994

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The top2-5 mutant of yeast topoisomerase II encodes an enzyme resistant to etoposide and amsacrine

The Journal of biological chemistry, 1993-09, Vol.268 (25), p.18586-18592

1993

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Overexpression of Type I Topoisomerases Sensitizes Yeast Cells to DNA Damage

The Journal of biological chemistry, 2001-07, Vol.276 (28), p.26708-26714

2001

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Yeast topoisomerase II mutants resistant to anti-topoisomerase agents : identification and characterization of new yeast topoisomerase II mutants selected for resistance to etoposide

Cancer research (Chicago, Ill.), 1994-06, Vol.54 (11), p.2943-2951

1994

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A Mutation in Human Topoisomerase II α Whose Expression Is Lethal in DNA Repair-deficient Yeast Cells

The Journal of biological chemistry, 2004-06, Vol.279 (25), p.25947-25954

2004

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DNA Topoisomerases as Targets for the Anticancer Drug TAS-103: Primary Cellular Target and DNA Cleavage Enhancement

Biochemistry (Easton), 1999-11, Vol.38 (47), p.15573-15579

1999

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Yeast systems for demonstrating the targets of anti-topoisomerase II agents

Methods in molecular biology (Clifton, N.J.), 2001, Vol.95, p.315

2001

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Antifungal Activity of Eupolauridine and Its Action on DNA Topoisomerases

Antimicrobial Agents and Chemotherapy, 2002-06, Vol.46 (6), p.1785-1792

2002

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Biologically Active Carbazole Alkaloids from Murraya koenigii

End-processing during non-homologous end-joining: a role for exonuclease 1

Antitopoisomerase drug action and resistance

Mechanisms of cell killing by drugs that trap covalent complexes between DNA topoisomerases and DNA

Aclacinomycin A stabilizes topoisomerase I covalent complexes

Cytotoxicity of quinolones toward eukaryotic cells. Identification of topoisomerase. II. As the primary cellular target for the quinolone CP-115,953 in yeast

Human small cell lung cancer NYH cells selected for resistance to the bisdioxopiperazine topoisomerase II catalytic inhibitor ICRF-187 demonstrate a functional R162Q mutation in the Walker A consensus ATP binding domain of the α isoform

A temperature sensitive topoisomerase II allele confers temperature dependent drug resistance on amsacrine and etoposide : a genetic system for determining the targets of topoisomerase II inhibitors

Amsacrine and etoposide hypersensitivity of yeast cells overexpressing DNA topoisomerase II

Metabolites of Daidzein and Genistein and Their Biological Activities

Yeast recombination pathways triggered by topoisomerase II-mediated DNA breaks

Chinese hamster ovary cells resistant to the topoisomerase II catalytic inhibitor ICRF-159 : A Tyr49Phe mutation confers high-level resistance to bisdioxopiperazines

Investigating the biological functions of DNA topoisomerases in eukaryotic cells

DNA topoisomerase II is the molecular target of bisdioxopiperazine derivatives ICRF-159 and ICRF-193 in Saccharomyces cerevisiae

A Novel Mechanism of Cell Killing by Anti-topoisomerase II Bisdioxopiperazines

DNA Repair Functions That Control Sensitivity to Topoisomerase-Targeting Drugs

Functional expression of human topoisomerase IIα in yeast : mutations at amino acids 450 or 803 of topoisomerase IIα result in enzymes that can confer resistance to anti-topoisomerase II agents

Using yeast to study resistance to topoisomerase II-targeting drugs

The top2-5 mutant of yeast topoisomerase II encodes an enzyme resistant to etoposide and amsacrine

Overexpression of Type I Topoisomerases Sensitizes Yeast Cells to DNA Damage

Yeast topoisomerase II mutants resistant to anti-topoisomerase agents : identification and characterization of new yeast topoisomerase II mutants selected for resistance to etoposide

A Mutation in Human Topoisomerase II α Whose Expression Is Lethal in DNA Repair-deficient Yeast Cells

DNA Topoisomerases as Targets for the Anticancer Drug TAS-103: Primary Cellular Target and DNA Cleavage Enhancement

Yeast systems for demonstrating the targets of anti-topoisomerase II agents

Antifungal Activity of Eupolauridine and Its Action on DNA Topoisomerases

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