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Preclinical activity of nanoliposomal irinotecan is governed by tumor deposition and intratumor prodrug conversion

Cancer research (Chicago, Ill.), 2014-12, Vol.74 (23), p.7003-7013

2014

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Identification and high-throughput genotyping of single nucleotide polymorphism markers in a non-model conifer (Abies nordmanniana (Steven) Spach)

Scientific reports, 2023-12, Vol.13 (1), p.22488-22488, Article 22488

2023

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Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data

Molecular systems biology, 2009, Vol.5 (1), p.239-n/a

2009

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Therapeutically targeting ErbB3: a key node in ligand-induced activation of the ErbB receptor-PI3K axis

Science signaling, 2009-06, Vol.2 (77), p.ra31

2009

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MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM

Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (15), p.7533-7542

2019

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HER2+ Cancer Cell Dependence on PI3K vs. MAPK Signaling Axes Is Determined by Expression of EGFR, ERBB3 and CDKN1B

PLoS computational biology, 2016-04, Vol.12 (4), p.e1004827-e1004827

2016

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Cyclophosphamide-Mediated Tumor Priming for Enhanced Delivery and Antitumor Activity of HER2-Targeted Liposomal Doxorubicin (MM-302)

Molecular cancer therapeutics, 2015-09, Vol.14 (9), p.2060-2071

2015

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Impact of intrinsic affinity on functional binding and biological activity of EGFR antibodies

Molecular cancer therapeutics, 2012-07, Vol.11 (7), p.1467-1476

2012

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The Response of Human Epithelial Cells to TNF Involves an Inducible Autocrine Cascade

Cell, 2006-03, Vol.124 (6), p.1225-1239

2006

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Insulin‐Like Growth Factor Promotes Cardiac Lineage Induction In Vitro by Selective Expansion of Early Mesoderm

Stem cells (Dayton, Ohio), 2014-06, Vol.32 (6), p.1493-1502

2014

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Multiplexed sandwich assays in microarray format

Journal of Immunological Methods, 2004-07, Vol.290 (1), p.107-120

2004

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Profiling Receptor Tyrosine Kinase Activation by Using Ab Microarrays

Proceedings of the National Academy of Sciences - PNAS, 2003-08, Vol.100 (16), p.9330-9335

2003

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Systems biology and combination therapy in the quest for clinical efficacy

Nature chemical biology, 2006-09, Vol.2 (9), p.458-466

2006

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Optimizing Properties of Antireceptor Antibodies Using Kinetic Computational Models and Experiments

Methods in Enzymology, 2012, Vol.502, p.67-87

2012

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Comprehensive optimization of a single-chain variable domain antibody fragment as a targeting ligand for a cytotoxic nanoparticle

mAbs, 2015-01, Vol.7 (1), p.42-52

2015

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Reviewing emerging markets: context, concepts and future research

International journal of emerging markets, 2018-11, Vol.13 (6), p.1679-1698

2018

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Antitumor activity of a novel bispecific antibody that targets the ErbB2/ErbB3 oncogenic unit and inhibits heregulin-induced activation of ErbB3

Molecular cancer therapeutics, 2012-03, Vol.11 (3), p.582-593

2012

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Selection of tumor-specific internalizing human antibodies from phage libraries

Journal of molecular biology, 2000-09, Vol.301 (5), p.1149-1161

2000

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Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models

Cancer research (Chicago, Ill.), 2006-07, Vol.66 (13), p.6732-6740

2006

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An ErbB3 Antibody, MM-121, Is Active in Cancers with Ligand-Dependent Activation

Cancer research (Chicago, Ill.), 2010-03, Vol.70 (6), p.2485-2494

2010

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Computational modeling of ERBB2-amplified breast cancer identifies combined ErbB2/3 blockade as superior to the combination of MEK and AKT inhibitors

Science signaling, 2013-08, Vol.6 (288), p.ra68

2013

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Microsatellites used to establish full pedigree in a half-sib trial and correlation between number of male strobili and paternal success

Annals of forest science., 2010, Vol.67 (7), p.703-703

2010

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MM-141, an IGF-IR- and ErbB3-directed bispecific antibody, overcomes network adaptations that limit activity of IGF-IR inhibitors

Molecular cancer therapeutics, 2014-02, Vol.13 (2), p.410-425

2014

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Dual Inhibition of IGF-1R and ErbB3 Enhances the Activity of Gemcitabine and Nab-Paclitaxel in Preclinical Models of Pancreatic Cancer

Clinical cancer research, 2018-06, Vol.24 (12), p.2873-2885

2018

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Enhanced Targeting of the EGFR Network with MM-151, an Oligoclonal Anti-EGFR Antibody Therapeutic

Molecular cancer therapeutics, 2015-07, Vol.14 (7), p.1625-1636

2015

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Preclinical activity of nanoliposomal irinotecan is governed by tumor deposition and intratumor prodrug conversion

Identification and high-throughput genotyping of single nucleotide polymorphism markers in a non-model conifer (Abies nordmanniana (Steven) Spach)

Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data

Therapeutically targeting ErbB3: a key node in ligand-induced activation of the ErbB receptor-PI3K axis

MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM

HER2+ Cancer Cell Dependence on PI3K vs. MAPK Signaling Axes Is Determined by Expression of EGFR, ERBB3 and CDKN1B

Cyclophosphamide-Mediated Tumor Priming for Enhanced Delivery and Antitumor Activity of HER2-Targeted Liposomal Doxorubicin (MM-302)

Impact of intrinsic affinity on functional binding and biological activity of EGFR antibodies

The Response of Human Epithelial Cells to TNF Involves an Inducible Autocrine Cascade

Insulin‐Like Growth Factor Promotes Cardiac Lineage Induction In Vitro by Selective Expansion of Early Mesoderm

Multiplexed sandwich assays in microarray format

Profiling Receptor Tyrosine Kinase Activation by Using Ab Microarrays

Systems biology and combination therapy in the quest for clinical efficacy

Optimizing Properties of Antireceptor Antibodies Using Kinetic Computational Models and Experiments

Comprehensive optimization of a single-chain variable domain antibody fragment as a targeting ligand for a cytotoxic nanoparticle

Reviewing emerging markets: context, concepts and future research

Antitumor activity of a novel bispecific antibody that targets the ErbB2/ErbB3 oncogenic unit and inhibits heregulin-induced activation of ErbB3

Selection of tumor-specific internalizing human antibodies from phage libraries

Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models

An ErbB3 Antibody, MM-121, Is Active in Cancers with Ligand-Dependent Activation

Computational modeling of ERBB2-amplified breast cancer identifies combined ErbB2/3 blockade as superior to the combination of MEK and AKT inhibitors

Microsatellites used to establish full pedigree in a half-sib trial and correlation between number of male strobili and paternal success

MM-141, an IGF-IR- and ErbB3-directed bispecific antibody, overcomes network adaptations that limit activity of IGF-IR inhibitors

Dual Inhibition of IGF-1R and ErbB3 Enhances the Activity of Gemcitabine and Nab-Paclitaxel in Preclinical Models of Pancreatic Cancer

Enhanced Targeting of the EGFR Network with MM-151, an Oligoclonal Anti-EGFR Antibody Therapeutic

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