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The Influenza Virus Polymerase Complex: An Update on Its Structure, Functions, and Significance for Antiviral Drug Design

Medicinal research reviews, 2016-11, Vol.36 (6), p.1127-1173

2016

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Synthesis and Biological Evaluation of Novel (thio)semicarbazone-Based Benzimidazoles as Antiviral Agents against Human Respiratory Viruses

Molecules (Basel, Switzerland), 2020-03, Vol.25 (7), p.1487

2020

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Antiviral therapies on the horizon for influenza

Current opinion in pharmacology, 2016-10, Vol.30, p.106-115

2016

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The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airways

PLoS pathogens, 2021-04, Vol.17 (4), p.e1009500-e1009500

2021

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First Crystal Structures of Mycobacterium tuberculosis 6‑Oxopurine Phosphoribosyltransferase: Complexes with GMP and Pyrophosphate and with Acyclic Nucleoside Phosphonates Whose Prodrugs Have Antituberculosis Activity

Journal of medicinal chemistry, 2015-06, Vol.58 (11), p.4822-4838

2015

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Functional Analysis of Human and Feline Coronavirus Cross-Reactive Antibodies Directed Against the SARS-CoV-2 Fusion Peptide

Frontiers in immunology, 2022-01, Vol.12, p.790415

2022

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Inhibition of Hypoxanthine-Guanine Phosphoribosyltransferase by Acyclic Nucleoside Phosphonates: A New Class of Antimalarial Therapeutics

Journal of medicinal chemistry, 2009-07, Vol.52 (14), p.4391-4399

2009

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Clinical features and treatment of adenovirus infections

Reviews in medical virology, 2008-11, Vol.18 (6), p.357-374

2008

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Design of Plasmodium vivax Hypoxanthine-Guanine Phosphoribosyltransferase Inhibitors as Potential Antimalarial Therapeutics

ACS chemical biology, 2018-01, Vol.13 (1), p.82-90

2018

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Inhibition of the Escherichia coli 6‑Oxopurine Phosphoribosyltransferases by Nucleoside Phosphonates: Potential for New Antibacterial Agents

Journal of medicinal chemistry, 2013-09, Vol.56 (17), p.6967-6984

2013

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Update on Human Herpesvirus 6 Biology, Clinical Features, and Therapy

Clinical Microbiology Reviews, 2005-01, Vol.18 (1), p.217-245

2005

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First discovery of novel 3-hydroxy-quinazoline-2,4(1H,3H)-diones as specific anti-vaccinia and adenovirus agents via ‘privileged scaffold’ refining approach

Bioorganic & medicinal chemistry letters, 2016-11, Vol.26 (21), p.5182-5186

2016

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Pyrrolidine nucleoside bisphosphonates as antituberculosis agents targeting hypoxanthine-guanine phosphoribosyltransferase

European journal of medicinal chemistry, 2018-11, Vol.159, p.10-22

2018

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Hemagglutinin Cleavability, Acid Stability, and Temperature Dependence Optimize Influenza B Virus for Replication in Human Airways

Journal of virology, 2019-12, Vol.94 (1)

2019

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Mutational Analysis of the Binding Pockets of the Diketo Acid Inhibitor L-742,001 in the Influenza Virus PA Endonuclease

Journal of Virology, 2013-10, Vol.87 (19), p.10524-10538

2013

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Investigation of the salicylaldehyde thiosemicarbazone scaffold for inhibition of influenza virus PA endonuclease

Journal of biological inorganic chemistry, 2015-10, Vol.20 (7), p.1109-1121

2015

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Impact of SARS-CoV-2 Spike Mutations on Its Activation by TMPRSS2 and the Alternative TMPRSS13 Protease

mBio, 2022-08, Vol.13 (4), p.e0137622-e0137622

2022

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Amphiphilic Sialic Acid Derivatives as Potential Dual-Specific Inhibitors of Influenza Hemagglutinin and Neuraminidase

International journal of molecular sciences, 2023-12, Vol.24 (24), p.17268

2023

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Novel Inhibitors of Influenza Virus Fusion: Structure-Activity Relationship and Interaction with the Viral Hemagglutinin

Journal of Virology, 2010-05, Vol.84 (9), p.4277-4288

2010

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Novel Polymyxin-Inspired Peptidomimetics Targeting the SARS-CoV-2 Spike:hACE2 Interface

International journal of molecular sciences, 2023-05, Vol.24 (10), p.8765

2023

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Synthesis and Anticancer and Antiviral Activities of C-2′-Branched Arabinonucleosides

International journal of molecular sciences, 2022-10, Vol.23 (20), p.12566

2022

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Cidofovir is active against human papillomavirus positive and negative head and neck and cervical tumor cells by causing DNA damage as one of its working mechanisms

Oncotarget, 2016-07, Vol.7 (30), p.47302-47318

2016

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Semisynthetic teicoplanin derivatives with dual antimicrobial activity against SARS-CoV-2 and multiresistant bacteria

Scientific reports, 2022-09, Vol.12 (1), p.16001-16001, Article 16001

2022

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Early oseltamivir reduces risk for influenza-associated aspergillosis in a double-hit murine model

Virulence, 2021-12, Vol.12 (1), p.2493-2508

2021

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Synthesis and biological evaluation of lipophilic teicoplanin pseudoaglycon derivatives containing a substituted triazole function

Journal of antibiotics, 2017-02, Vol.70 (2), p.152-157

2017

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The Influenza Virus Polymerase Complex: An Update on Its Structure, Functions, and Significance for Antiviral Drug Design

Synthesis and Biological Evaluation of Novel (thio)semicarbazone-Based Benzimidazoles as Antiviral Agents against Human Respiratory Viruses

Antiviral therapies on the horizon for influenza

The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airways

First Crystal Structures of Mycobacterium tuberculosis 6‑Oxopurine Phosphoribosyltransferase: Complexes with GMP and Pyrophosphate and with Acyclic Nucleoside Phosphonates Whose Prodrugs Have Antituberculosis Activity

Functional Analysis of Human and Feline Coronavirus Cross-Reactive Antibodies Directed Against the SARS-CoV-2 Fusion Peptide

Inhibition of Hypoxanthine-Guanine Phosphoribosyltransferase by Acyclic Nucleoside Phosphonates: A New Class of Antimalarial Therapeutics

Clinical features and treatment of adenovirus infections

Design of Plasmodium vivax Hypoxanthine-Guanine Phosphoribosyltransferase Inhibitors as Potential Antimalarial Therapeutics

Inhibition of the Escherichia coli 6‑Oxopurine Phosphoribosyltransferases by Nucleoside Phosphonates: Potential for New Antibacterial Agents

Update on Human Herpesvirus 6 Biology, Clinical Features, and Therapy

First discovery of novel 3-hydroxy-quinazoline-2,4(1H,3H)-diones as specific anti-vaccinia and adenovirus agents via ‘privileged scaffold’ refining approach

Pyrrolidine nucleoside bisphosphonates as antituberculosis agents targeting hypoxanthine-guanine phosphoribosyltransferase

Hemagglutinin Cleavability, Acid Stability, and Temperature Dependence Optimize Influenza B Virus for Replication in Human Airways

Mutational Analysis of the Binding Pockets of the Diketo Acid Inhibitor L-742,001 in the Influenza Virus PA Endonuclease

Investigation of the salicylaldehyde thiosemicarbazone scaffold for inhibition of influenza virus PA endonuclease

Impact of SARS-CoV-2 Spike Mutations on Its Activation by TMPRSS2 and the Alternative TMPRSS13 Protease

Amphiphilic Sialic Acid Derivatives as Potential Dual-Specific Inhibitors of Influenza Hemagglutinin and Neuraminidase

Novel Inhibitors of Influenza Virus Fusion: Structure-Activity Relationship and Interaction with the Viral Hemagglutinin

Novel Polymyxin-Inspired Peptidomimetics Targeting the SARS-CoV-2 Spike:hACE2 Interface

Synthesis and Anticancer and Antiviral Activities of C-2′-Branched Arabinonucleosides

Cidofovir is active against human papillomavirus positive and negative head and neck and cervical tumor cells by causing DNA damage as one of its working mechanisms

Semisynthetic teicoplanin derivatives with dual antimicrobial activity against SARS-CoV-2 and multiresistant bacteria

Early oseltamivir reduces risk for influenza-associated aspergillosis in a double-hit murine model

Synthesis and biological evaluation of lipophilic teicoplanin pseudoaglycon derivatives containing a substituted triazole function

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