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Identification of new drug targets and resistance mechanisms in Mycobacterium tuberculosis

PloS one, 2013-09, Vol.8 (9), p.e75245-e75245

2013

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Mycobacterium smegmatis NucS-promoted DNA mismatch repair involves limited resection by a 5′-3′ exonuclease and is independent of homologous recombination and NHEJ

Nucleic acids research, 2024-10, Vol.52 (20), p.12308-12323

2024

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The Oxidative Stress Network of Mycobacterium tuberculosis Reveals Coordination between Radical Detoxification Systems

Cell host & microbe, 2015-06, Vol.17 (6), p.829-837

2015

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Subpolar addition of new cell wall is directed by DivIVA in mycobacteria

Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (31), p.E3243-E3251

2014

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ORBIT: a New Paradigm for Genetic Engineering of Mycobacterial Chromosomes

mBio, 2018-12, Vol.9 (6)

2018

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The structure of the endogenous ESX-3 secretion system

eLife, 2019-12, Vol.8

2019

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A natural polymorphism of Mycobacterium tuberculosis in the esxH gene disrupts immunodomination by the TB10.4-specific CD8 T cell response

PLoS pathogens, 2020-10, Vol.16 (10), p.e1009000-e1009000

2020

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Use of Bacteriophage λ Recombination Functions To Promote Gene Replacement in Escherichia coli

Journal of Bacteriology, 1998-04, Vol.180 (8), p.2063-2071

Murphy, K C

1998

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Structural/functional analysis of the human OXR1 protein: identification of exon 8 as the anti-oxidant encoding function

BMC molecular biology, 2012-08, Vol.13 (1), p.26-26

2012

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λ Recombination and Recombineering

Ecosal plus, 2016-05, Vol.7 (1)

2016

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Mycobacterial recombineering

Methods in molecular biology (Clifton, N.J.), 2015, Vol.1285, p.177

2015

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Phage Recombinases and Their Applications

Advances in Virus Research, 2012, Vol.83, p.367-414

Murphy, Kenan C.

2012

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Transcriptional regulators of the GAD acid stress island are carried by effector protein‐encoding prophages and indirectly control type III secretion in enterohemorrhagic Escherichia coli O157:H7

Molecular microbiology, 2011-06, Vol.80 (5), p.1349-1365

2011

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Large-scale chemical–genetics yields new M. tuberculosis inhibitor classes

Nature (London), 2019-07, Vol.571 (7763), p.72-78

2019

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N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis

Proceedings of the National Academy of Sciences - PNAS, 2016-08, Vol.113 (31), p.E4523-E4530

2016

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Phase variation as a major mechanism of adaptation in Mycobacterium tuberculosis complex

Proceedings of the National Academy of Sciences - PNAS, 2023-07, Vol.120 (28), p.e2301394120-e2301394120

2023

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Dam Methyltransferase Is Required for Stable Lysogeny of the Shiga Toxin (Stx2)-Encoding Bacteriophage 933W of Enterohemorrhagic Escherichia coli O157:H7

Journal of Bacteriology, 2008-01, Vol.190 (1), p.438-441

2008

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Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy

Proceedings of the National Academy of Sciences - PNAS, 2022-04, Vol.119 (15), p.e2201632119-e2201632119

2022

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Enhanced Actin Pedestal Formation by Enterohemorrhagic Escherichia coli O157:H7 Adapted to the Mammalian Host

Frontiers in microbiology, 2011-01, Vol.2, p.226-226

2011

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Structural and Genetic Analyses of the Mycobacterium tuberculosis Protein Kinase B Sensor Domain Identify a Potential Ligand-binding Site

The Journal of biological chemistry, 2016-10, Vol.291 (44), p.22961-22969

2016

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Lambda Red-mediated recombinogenic engineering of enterohemorrhagic and enteropathogenic E. coli

BMC molecular biology, 2003-12, Vol.4 (1), p.11-11, Article 11

2003

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The λ Gam Protein Inhibits RecBCD Binding to dsDNA Ends

Journal of molecular biology, 2007-08, Vol.371 (1), p.19-24

Murphy, Kenan C.

2007

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Identification of a novel prophage regulator in Escherichia coli controlling the expression of type III secretion

Molecular microbiology, 2012-01, Vol.83 (1), p.208-223

2012

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Increased adherence and actin pedestal formation by dam-deficient enterohaemorrhagic Escherichia coli O157:H7

Molecular microbiology, 2007-03, Vol.63 (5), p.1468-1481

2007

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Roles of RuvC and RecG in Phage λ Red-Mediated Recombination

Journal of Bacteriology, 1999-09, Vol.181 (17), p.5402-5408

1999

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Identification of new drug targets and resistance mechanisms in Mycobacterium tuberculosis

Mycobacterium smegmatis NucS-promoted DNA mismatch repair involves limited resection by a 5′-3′ exonuclease and is independent of homologous recombination and NHEJ

The Oxidative Stress Network of Mycobacterium tuberculosis Reveals Coordination between Radical Detoxification Systems

Subpolar addition of new cell wall is directed by DivIVA in mycobacteria

ORBIT: a New Paradigm for Genetic Engineering of Mycobacterial Chromosomes

The structure of the endogenous ESX-3 secretion system

A natural polymorphism of Mycobacterium tuberculosis in the esxH gene disrupts immunodomination by the TB10.4-specific CD8 T cell response

Use of Bacteriophage λ Recombination Functions To Promote Gene Replacement in Escherichia coli

Structural/functional analysis of the human OXR1 protein: identification of exon 8 as the anti-oxidant encoding function

λ Recombination and Recombineering

Mycobacterial recombineering

Phage Recombinases and Their Applications

Transcriptional regulators of the GAD acid stress island are carried by effector protein‐encoding prophages and indirectly control type III secretion in enterohemorrhagic Escherichia coli O157:H7

Large-scale chemical–genetics yields new M. tuberculosis inhibitor classes

N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis

Phase variation as a major mechanism of adaptation in Mycobacterium tuberculosis complex

Dam Methyltransferase Is Required for Stable Lysogeny of the Shiga Toxin (Stx2)-Encoding Bacteriophage 933W of Enterohemorrhagic Escherichia coli O157:H7

Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy

Enhanced Actin Pedestal Formation by Enterohemorrhagic Escherichia coli O157:H7 Adapted to the Mammalian Host

Structural and Genetic Analyses of the Mycobacterium tuberculosis Protein Kinase B Sensor Domain Identify a Potential Ligand-binding Site

Lambda Red-mediated recombinogenic engineering of enterohemorrhagic and enteropathogenic E. coli

The λ Gam Protein Inhibits RecBCD Binding to dsDNA Ends

Identification of a novel prophage regulator in Escherichia coli controlling the expression of type III secretion

Increased adherence and actin pedestal formation by dam-deficient enterohaemorrhagic Escherichia coli O157:H7

Roles of RuvC and RecG in Phage λ Red-Mediated Recombination

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