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Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells

Cancer research (Chicago, Ill.), 2006-02, Vol.66 (3), p.1630-1639

2006

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Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity

Molecular cancer therapeutics, 2007-07, Vol.6 (7), p.2012-2021

2007

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Anti-tumor activity of GW572016: a dual tyrosine kinase inhibitor blocks EGF activation of EGFR/erbB2 and downstream Erk1/2 and AKT pathways

Oncogene, 2002-09, Vol.21 (41), p.6255-6263

2002

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Evaluation of Lapatinib and Topotecan Combination Therapy: Tissue Culture, Murine Xenograft, and Phase I Clinical Trial Data

Clinical cancer research, 2008-12, Vol.14 (23), p.7900-7908

2008

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The Effects of the Novel, Reversible Epidermal Growth Factor Receptor/ErbB-2 Tyrosine Kinase Inhibitor, GW2016, on the Growth of Human Normal and Tumor-derived Cell Lines in Vitro and in Vivo

Molecular cancer therapeutics, 2001-12, Vol.1 (2), p.85-94

2001

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Synthesis and stereochemical effects of pyrrolidinyl-acetylenic thieno[3,2- d]pyrimidines as EGFR and ErbB-2 inhibitors

Bioorganic & medicinal chemistry letters, 2009, Vol.19 (1), p.21-26

2009

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The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: Potential therapy for cancer

Cancer research (Chicago, Ill.), 2001-10, Vol.61 (19), p.7196-7203

2001

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Abstract 2215: Pembrolizumab and ipilimumab reduce human RKO colon carcinoma tumor growth in HLA matched CD34-NSG humanized mice

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.2215-2215

2016

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Thienopyrimidine-based dual EGFR/ErbB-2 inhibitors

Bioorganic & medicinal chemistry letters, 2009-02, Vol.19 (3), p.817-820

2009

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Novel patient-derived xenograft mouse model for pancreatic acinar cell carcinoma demonstrates single agent activity of oxaliplatin

Journal of translational medicine, 2016-05, Vol.14 (1), p.129, Article 129

2016

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Formoterol fumarate and roxithromycin effects on muscle mass in an animal model of cancer cachexia

Oncology reports, 2008-05, Vol.19 (5), p.1113-1121

2008

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Abstract C110: Evaluation of immune cell populations in checkpoint inhibitor responsive syngeneic models

Molecular cancer therapeutics, 2015-12, Vol.14 (12_Supplement_2), p.C110-C110

2015

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Abstract 2064: Mass Spectrometry Imaging of therapeutic antibodies: Distribution of unlabeled trastuzumab in CB.17 SCID mice implanted with the human breast BT474 xenograft

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.2064-2064

2014

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Abstract 3362: Systematic evaluation of immune checkpoint inhibitors

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.3362-3362

2015

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Abstract 1458: Characterization of novel thyroid PDX models and their response to combination therapies

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.1458-1458

2015

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Abstract 1475: Therapeutic responses in a novel patient-derived xenograft mouse model for rare acinar cell pancreatic carcinoma

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.1475-1475

2015

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Abstract 1453: Methods for developing patient derived xenografts in athymic nude mice

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.1453-1453

2015

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Abstract 5095: Differential sensitivity to dietary restriction in xenograft models harboring PI3K pathway mutations in nude mice

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.5095-5095

2010

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Abstract B79: Antitumor activity of lapatinib as a single agent and in combination with capecitabine in a HER2-amplified human gastric tumor model

Molecular cancer therapeutics, 2009-12, Vol.8 (12_Supplement), p.B79-B79

2009

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In vivo and in vitro metabolism of 5-deazaacyclotetrahydrofolate, an acyclic tetrahydrofolate analogue

Cancer research (Chicago, Ill.), 1990-06, Vol.50 (11), p.3207-3211

1990

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Synthesis and biological evaluation of N.alpha.-(5-deaza-5,6,7,8-tetrahydropteroyl)-L-ornithine

Journal of medicinal chemistry, 1992-05, Vol.35 (11), p.2002-2006

1992

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Symptom Variability and Early Symptom Regression in the MAPP Study: A Prospective Study of Urological Chronic Pelvic Pain Syndrome

The Journal of urology, 2016-11, Vol.196 (5), p.1450-1455

2016

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Isolation and characterization of caseins from rat milk

Journal of dairy science, 1981-04, Vol.64 (4), p.559-567

1981

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Composition of milk of the sea otter ( Enhydra lutris)

Comparative biochemistry and physiology. A, Comparative physiology, 1981, Vol.70 (3), p.375-379

1981

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Anti-tumor activity of GW572016: a dual tyrosine kinase inhibitor blocks EGF activation of EGFR/erbB2 and downstream Erkl/2 and AKT pathways

Oncogene, 2002, Vol.21 (41), p.6255-6263

2002

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Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells

Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity

Anti-tumor activity of GW572016: a dual tyrosine kinase inhibitor blocks EGF activation of EGFR/erbB2 and downstream Erk1/2 and AKT pathways

Evaluation of Lapatinib and Topotecan Combination Therapy: Tissue Culture, Murine Xenograft, and Phase I Clinical Trial Data

The Effects of the Novel, Reversible Epidermal Growth Factor Receptor/ErbB-2 Tyrosine Kinase Inhibitor, GW2016, on the Growth of Human Normal and Tumor-derived Cell Lines in Vitro and in Vivo

Synthesis and stereochemical effects of pyrrolidinyl-acetylenic thieno[3,2- d]pyrimidines as EGFR and ErbB-2 inhibitors

The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: Potential therapy for cancer

Abstract 2215: Pembrolizumab and ipilimumab reduce human RKO colon carcinoma tumor growth in HLA matched CD34-NSG humanized mice

Thienopyrimidine-based dual EGFR/ErbB-2 inhibitors

Novel patient-derived xenograft mouse model for pancreatic acinar cell carcinoma demonstrates single agent activity of oxaliplatin

Formoterol fumarate and roxithromycin effects on muscle mass in an animal model of cancer cachexia

Abstract C110: Evaluation of immune cell populations in checkpoint inhibitor responsive syngeneic models

Abstract 2064: Mass Spectrometry Imaging of therapeutic antibodies: Distribution of unlabeled trastuzumab in CB.17 SCID mice implanted with the human breast BT474 xenograft

Abstract 3362: Systematic evaluation of immune checkpoint inhibitors

Abstract 1458: Characterization of novel thyroid PDX models and their response to combination therapies

Abstract 1475: Therapeutic responses in a novel patient-derived xenograft mouse model for rare acinar cell pancreatic carcinoma

Abstract 1453: Methods for developing patient derived xenografts in athymic nude mice

Abstract 5095: Differential sensitivity to dietary restriction in xenograft models harboring PI3K pathway mutations in nude mice

Abstract B79: Antitumor activity of lapatinib as a single agent and in combination with capecitabine in a HER2-amplified human gastric tumor model

In vivo and in vitro metabolism of 5-deazaacyclotetrahydrofolate, an acyclic tetrahydrofolate analogue

Synthesis and biological evaluation of N.alpha.-(5-deaza-5,6,7,8-tetrahydropteroyl)-L-ornithine

Symptom Variability and Early Symptom Regression in the MAPP Study: A Prospective Study of Urological Chronic Pelvic Pain Syndrome

Isolation and characterization of caseins from rat milk

Composition of milk of the sea otter ( Enhydra lutris)

Anti-tumor activity of GW572016: a dual tyrosine kinase inhibitor blocks EGF activation of EGFR/erbB2 and downstream Erkl/2 and AKT pathways

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