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Apremilast, a cAMP phosphodiesterase‐4 inhibitor, demonstrates anti‐inflammatory activity in vitro and in a model of psoriasis

British journal of pharmacology, 2010-02, Vol.159 (4), p.842-855

2010

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Novel thalidomide analogues display anti-angiogenic activity independently of immunomodulatory effects

British journal of cancer, 2002-11, Vol.87 (10), p.1166-1172

2002

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Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha

The Journal of immunology (1950), 1999-07, Vol.163 (1), p.380-386

1999

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Protective Antitumor Immunity Induced by a Costimulatory Thalidomide Analog in Conjunction with Whole Tumor Cell Vaccination Is Mediated by Increased Th1-Type Immunity

The Journal of immunology (1950), 2002-05, Vol.168 (10), p.4914-4919

2002

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Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity

Cellular signalling, 2014-09, Vol.26 (9), p.2016-2029

2014

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A novel subclass of thalidomide analogue with anti-solid tumor activity in which caspase-dependent apoptosis is associated with altered expression of bcl-2 family proteins

Cancer research (Chicago, Ill.), 2003-02, Vol.63 (3), p.593-599

2003

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Selection of novel analogs of thalidomide with enhanced tumor necrosis factor alpha inhibitory activity

Molecular medicine (Cambridge, Mass.), 1996-07, Vol.2 (4), p.506-515

1996

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Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma

Blood, 2001-07, Vol.98 (1), p.210-216

2001

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Selective cytokine inhibitory drugs with enhanced antiangiogenic activity control tumor growth through vascular inhibition

Cancer research (Chicago, Ill.), 2003-12, Vol.63 (23), p.8073-8078

2003

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Chiral inversion of the second generation IMiD™ CC-4047 (ACTIMID™) in human plasma and phosphate-buffered saline

Chirality (New York, N.Y.), 2003, Vol.15 (4), p.348-351

2003

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Thalidomide and Lenalidomide Extend Survival in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

The Journal of neuroscience, 2006-03, Vol.26 (9), p.2467-2473

2006

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Thalidomide and thalidomide analogs reduce HIV type 1 replication in human macrophages in vitro

AIDS research and human retroviruses, 1997-07, Vol.13 (10), p.857-863

1997

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Phase I study to determine the safety, tolerability and immunostimulatory activity of thalidomide analogue CC-5013 in patients with metastatic malignant melanoma and other advanced cancers

British journal of cancer, 2004-03, Vol.90 (5), p.955-961

2004

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First Report of the Causal Agent of Huanglongbing ("Candidatus Liberibacter asiaticus") in Brazil

Plant disease, 2004-12, Vol.88 (12), p.1382-1382

2004

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Enhancement of cytokine production and AP-1 transcriptional activity in T cells by thalidomide-related immunomodulatory drugs

The Journal of pharmacology and experimental therapeutics, 2003-06, Vol.305 (3), p.1222-1232

2003

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Amino-substituted thalidomide analogs: Potent inhibitors of TNF-α production

Bioorganic & medicinal chemistry letters, 1999-06, Vol.9 (11), p.1625-1630

1999

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Effect of 3-fluorothalidomide and 3-methylthalidomide enantiomers on tumor necrosis factor production and antitumor responses to the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)

Oncology research, 2003, Vol.14 (2), p.75-82

2003

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The synthetic compound CC-5079 is a potent inhibitor of tubulin polymerization and tumor necrosis factor-α production with antitumor activity

Cancer research (Chicago, Ill.), 2006-01, Vol.66 (2), p.951-959

2006

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Immunomodulatory drugs inhibit expression of cyclooxygenase-2 from TNF-α, IL-1β, and LPS-stimulated human PBMC in a partially IL-10-dependent manner

Cellular immunology, 2004-08, Vol.230 (2), p.81-88

2004

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α-Fluoro-substituted thalidomide analogues

Bioorganic & medicinal chemistry letters, 2003-10, Vol.13 (20), p.3415-3417

2003

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Immunomodulatory Drugs (IMiDs) Increase the Production of IL-2 from Stimulated T Cells by Increasing PKC-θ Activation and Enhancing the DNA-Binding Activity of AP-1 but Not NF-κB, OCT-1, or NF-AT

Journal of interferon & cytokine research, 2005-10, Vol.25 (10), p.604-616

2005

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Structural Modifications of Thalidomide Produce Analogs with Enhanced Tumor Necrosis Factor Inhibitory Activity

Journal of medicinal chemistry, 1996-08, Vol.39 (17), p.3238-3240

1996

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Digital Tools for Anatolian Studies: Hethitologie-Portal Mainz and the Project Das Corpus der hethitischen Festrituale

Bulletin de la Société de linguistique de Paris, 2022-01, Vol.117 (1), p.131

2022

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A Concise Two-Step Synthesis of Thalidomide

Organic process research & development, 1999-03, Vol.3 (2), p.139-140

1999

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Rectal Impaction With Epoxy Resin: A Case Report

Journal of gastrointestinal surgery, 2005-05, Vol.9 (5), p.747-749

2005

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Apremilast, a cAMP phosphodiesterase‐4 inhibitor, demonstrates anti‐inflammatory activity in vitro and in a model of psoriasis

Novel thalidomide analogues display anti-angiogenic activity independently of immunomodulatory effects

Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha

Protective Antitumor Immunity Induced by a Costimulatory Thalidomide Analog in Conjunction with Whole Tumor Cell Vaccination Is Mediated by Increased Th1-Type Immunity

Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity

A novel subclass of thalidomide analogue with anti-solid tumor activity in which caspase-dependent apoptosis is associated with altered expression of bcl-2 family proteins

Selection of novel analogs of thalidomide with enhanced tumor necrosis factor alpha inhibitory activity

Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma

Selective cytokine inhibitory drugs with enhanced antiangiogenic activity control tumor growth through vascular inhibition

Chiral inversion of the second generation IMiD™ CC-4047 (ACTIMID™) in human plasma and phosphate-buffered saline

Thalidomide and Lenalidomide Extend Survival in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

Thalidomide and thalidomide analogs reduce HIV type 1 replication in human macrophages in vitro

Phase I study to determine the safety, tolerability and immunostimulatory activity of thalidomide analogue CC-5013 in patients with metastatic malignant melanoma and other advanced cancers

First Report of the Causal Agent of Huanglongbing ("Candidatus Liberibacter asiaticus") in Brazil

Enhancement of cytokine production and AP-1 transcriptional activity in T cells by thalidomide-related immunomodulatory drugs

Amino-substituted thalidomide analogs: Potent inhibitors of TNF-α production

Effect of 3-fluorothalidomide and 3-methylthalidomide enantiomers on tumor necrosis factor production and antitumor responses to the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)

The synthetic compound CC-5079 is a potent inhibitor of tubulin polymerization and tumor necrosis factor-α production with antitumor activity

Immunomodulatory drugs inhibit expression of cyclooxygenase-2 from TNF-α, IL-1β, and LPS-stimulated human PBMC in a partially IL-10-dependent manner

α-Fluoro-substituted thalidomide analogues

Immunomodulatory Drugs (IMiDs) Increase the Production of IL-2 from Stimulated T Cells by Increasing PKC-θ Activation and Enhancing the DNA-Binding Activity of AP-1 but Not NF-κB, OCT-1, or NF-AT

Structural Modifications of Thalidomide Produce Analogs with Enhanced Tumor Necrosis Factor Inhibitory Activity

Digital Tools for Anatolian Studies: Hethitologie-Portal Mainz and the Project Das Corpus der hethitischen Festrituale

A Concise Two-Step Synthesis of Thalidomide

Rectal Impaction With Epoxy Resin: A Case Report

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