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Rapamycin passes the torch: a new generation of mTOR inhibitors

Nature reviews. Drug discovery, 2011-11, Vol.10 (11), p.868-880

2011

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Dual Inhibition of the Lactate Transporters MCT1 and MCT4 Is Synthetic Lethal with Metformin due to NAD+ Depletion in Cancer Cells

Cell reports (Cambridge), 2018-12, Vol.25 (11), p.3047-3058.e4

2018

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BRF1 Protein Turnover and mRNA Decay Activity Are Regulated by Protein Kinase B at the Same Phosphorylation Sites

Molecular and Cellular Biology, 2006-12, Vol.26 (24), p.9497-9507

2006

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The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signaling

PLoS biology, 2007-01, Vol.5 (1), p.e5-e5

2007

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Syrosingopine sensitizes cancer cells to killing by metformin

Science advances, 2016-12, Vol.2 (12), p.e1601756-e1601756

2016

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The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B

The EMBO journal, 2004-12, Vol.23 (24), p.4760-4769

2004

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A Constitutive Decay Element Promotes Tumor Necrosis Factor Alpha mRNA Degradation via an AU-Rich Element-Independent Pathway

Molecular and Cellular Biology, 2003-05, Vol.23 (10), p.3506-3515

2003

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Parallel and Independent Regulation of Interleukin-3 mRNA Turnover by Phosphatidylinositol 3-Kinase and p38 Mitogen-Activated Protein Kinase

Molecular and Cellular Biology, 2001-09, Vol.21 (17), p.5778-5789

2001

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A novel mechanism of tumor suppression by destabilizing AU-rich growth factor mRNA

Oncogene, 2003-06, Vol.22 (23), p.3554-3561

2003

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Retraction: The RNA-Binding Protein KSRP Promotes Decay of β-Catenin mRNA and Is Inactivated by PI3K-AKT Signaling

PLoS biology, 2015-11, Vol.13 (11), p.e1002314-e1002314

2015

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Somatic mRNA Turnover Mutants Implicate Tristetraprolin in the Interleukin-3 mRNA Degradation Pathway

Molecular and Cellular Biology, 2000-06, Vol.20 (11), p.3753-3763

2000

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mRNA stability and cancer: an emerging link?

Expert opinion on biological therapy, 2007-10, Vol.7 (10), p.1515-1529

2007

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RTE and CTE mRNA export elements synergistically increase expression of unstable, Rev-dependent HIV and SIV mRNAs

Retrovirology, 2006-01, Vol.3 (1), p.6-6, Article 6

2006

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Production of the haemopoietic growth factors GM-CSF and interleukin-3 by mast cells in response to IgE receptor-mediated activation

Nature (London), 1989-05, Vol.339 (6220), p.150-152

1989

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Tristetraprolin inhibits Ras-dependent tumor vascularization by inducing vascular endothelial growth factor mRNA degradation

Molecular biology of the cell, 2007-11, Vol.18 (11), p.4648-4658

2007

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A KH Domain RNA Binding Protein, KSRP, Promotes ARE-Directed mRNA Turnover by Recruiting the Degradation Machinery

Molecular cell, 2004-06, Vol.14 (5), p.571-583

2004

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Global analysis of differential gene expression after transformation with the v-H-ras oncogene in a murine tumor model

Oncogene, 2001-05, Vol.20 (22), p.2854-2858

2001

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AU Binding Proteins Recruit the Exosome to Degrade ARE-Containing mRNAs

Cell, 2001-11, Vol.107 (4), p.451-464

2001

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Roles of AUF1 isoforms, HuR and BRF1 in ARE-dependent mRNA turnover studied by RNA interference

Nucleic acids research, 2004, Vol.32 (4), p.1279-1288

2004

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The Wnt/β-Catenin→Pitx2 Pathway Controls the Turnover of Pitx2 and Other Unstable mRNAs

Molecular cell, 2003-11, Vol.12 (5), p.1201-1211

2003

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Search for oncogenic regulators in an autocrine tumor model using differential display PCR : Identification of novel candidate genes including the calcium channel mtrp6

Oncogene, 1999-02, Vol.18 (7), p.1487-1494

1999

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The ARE‐dependent mRNA‐destabilizing activity of BRF1 is regulated by protein kinase B

The EMBO journal, 2004-12, Vol.23 (24), p.4760-4769

2004

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Erratum: Global analysis of differential gene expression after transformation with the v-H-ras oncogene in a murine tumor model

Oncogene, 2001-08, Vol.20 (35), p.4916-4916

2001

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Functional cloning of BRF1, a regulator of ARE-dependent mRNA turnover

The EMBO journal, 2002-09, Vol.21 (17), p.4709-4718

2002

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Cyclosporin A Promotes Translational Silencing of Autocrine Interleukin-3 via Ribosome-Associated Deadenylation

Molecular and Cellular Biology, 1999-01, Vol.19 (1), p.889-898

1999

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Rapamycin passes the torch: a new generation of mTOR inhibitors

Dual Inhibition of the Lactate Transporters MCT1 and MCT4 Is Synthetic Lethal with Metformin due to NAD+ Depletion in Cancer Cells

BRF1 Protein Turnover and mRNA Decay Activity Are Regulated by Protein Kinase B at the Same Phosphorylation Sites

The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signaling

Syrosingopine sensitizes cancer cells to killing by metformin

The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B

A Constitutive Decay Element Promotes Tumor Necrosis Factor Alpha mRNA Degradation via an AU-Rich Element-Independent Pathway

Parallel and Independent Regulation of Interleukin-3 mRNA Turnover by Phosphatidylinositol 3-Kinase and p38 Mitogen-Activated Protein Kinase

A novel mechanism of tumor suppression by destabilizing AU-rich growth factor mRNA

Retraction: The RNA-Binding Protein KSRP Promotes Decay of β-Catenin mRNA and Is Inactivated by PI3K-AKT Signaling

Somatic mRNA Turnover Mutants Implicate Tristetraprolin in the Interleukin-3 mRNA Degradation Pathway

mRNA stability and cancer: an emerging link?

RTE and CTE mRNA export elements synergistically increase expression of unstable, Rev-dependent HIV and SIV mRNAs

Production of the haemopoietic growth factors GM-CSF and interleukin-3 by mast cells in response to IgE receptor-mediated activation

Tristetraprolin inhibits Ras-dependent tumor vascularization by inducing vascular endothelial growth factor mRNA degradation

A KH Domain RNA Binding Protein, KSRP, Promotes ARE-Directed mRNA Turnover by Recruiting the Degradation Machinery

Global analysis of differential gene expression after transformation with the v-H-ras oncogene in a murine tumor model

AU Binding Proteins Recruit the Exosome to Degrade ARE-Containing mRNAs

Roles of AUF1 isoforms, HuR and BRF1 in ARE-dependent mRNA turnover studied by RNA interference

The Wnt/β-Catenin→Pitx2 Pathway Controls the Turnover of Pitx2 and Other Unstable mRNAs

Search for oncogenic regulators in an autocrine tumor model using differential display PCR : Identification of novel candidate genes including the calcium channel mtrp6

The ARE‐dependent mRNA‐destabilizing activity of BRF1 is regulated by protein kinase B

Erratum: Global analysis of differential gene expression after transformation with the v-H-ras oncogene in a murine tumor model

Functional cloning of BRF1, a regulator of ARE-dependent mRNA turnover

Cyclosporin A Promotes Translational Silencing of Autocrine Interleukin-3 via Ribosome-Associated Deadenylation

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