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Inhibition of BUB1 Kinase by BAY 1816032 Sensitizes Tumor Cells toward Taxanes, ATR, and PARP Inhibitors In Vitro and In Vivo

Clinical cancer research, 2019-02, Vol.25 (4), p.1404-1414

2019

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Potential and Limits of Kidney Cells for Evaluation of Renal Excretion

Pharmaceuticals (Basel, Switzerland), 2021-09, Vol.14 (9), p.908

2021

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Preclinical evaluation of BAY 1075553, a novel super(18)F-labelled inhibitor of prostate-specific membrane antigen for PET imaging of prostate cancer

European journal of nuclear medicine and molecular imaging, 2014-01, Vol.41 (1), p.89-101

2014

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Gene expression profiling of scrapie-infected brain tissue

Biochemical and biophysical research communications, 2004-10, Vol.323 (2), p.556-564

2004

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Preclinical evaluation of BAY 1075553, a novel 18F-labelled inhibitor of prostate-specific membrane antigen for PET imaging of prostate cancer

European journal of nuclear medicine and molecular imaging, 2014, Vol.41 (1), p.89-101

2014

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Abstract 4851: Second generation 2,3-dihydroimidazo[1,2-c]quinazoline PI3K inhibitors: development of BAY 1082439, a novel balanced PI3Ká / PI3Kâ inhibitor

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4851-4851

2016

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Abstract 287: BAY 1816032, a novel BUB1 kinase inhibitor with potent antitumor activity

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.287-287

2017

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Preclinical evaluation of BAY 1075553, a novel (18)F-labelled inhibitor of prostate-specific membrane antigen for PET imaging of prostate cancer

European journal of nuclear medicine and molecular imaging, 2014-01, Vol.41 (1), p.89

2014

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Abstract 2718: Synthesis and characterization of novel benzylpyrazole-based BUB1 kinase inhibitors with anti-tumor activity

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.2718-2718

2016

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Expression of the APP gene family in brain cells, brain development and aging

Gerontology (Basel), 1997-01, Vol.43 (1-2), p.119-131

1997

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Preclinical evaluation of BAY 1075553, a novel ^sup 18^F-labelled inhibitor of prostate-specific membrane antigen for PET imaging of prostate cancer

European journal of nuclear medicine and molecular imaging, 2014-01, Vol.41 (1), p.89

2014

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Mechanisms of amyloid deposition in Alzheimer's disease

Annals of the New York Academy of Sciences, 1991, Vol.640 (1), p.129-139

1991

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Amyloid-like properties of peptides flanking the epitope of amyloid precursor protein-specific monoclonal antibody 22C11

The Journal of biological chemistry, 1993-12, Vol.268 (35), p.26571-26577

1993

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Amyloid precursor protein secretion and βA4 amyloid generation are not mutually exclusive

FEBS letters, 1994-08, Vol.349 (2), p.210-214

1994

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Identification and differential expression of a novel alternative splice isoform of the beta A4 amyloid precursor protein (APP) mRNA in leukocytes and brain microglial cells

The Journal of biological chemistry, 1992-05, Vol.267 (15), p.10804-10809

1992

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Regulation and Expression of the Alzheimer's β/A4 Amyloid Protein Precursor in Health, Disease, and Down's Syndrome

Annals of the New York Academy of Sciences, 1993-09, Vol.695 (1), p.91-102

1993

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Extracellular Matrix Influences the Biogenesis of Amyloid Precursor Protein in Microglial Cells (∗)

The Journal of biological chemistry, 1995-03, Vol.270 (13), p.7104-7110

1995

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Cerebrospinal Fluid Levels of Amyloid Precursor Protein and Amyloid β-Peptide in Alzheimer’s Disease and Major Depression – Inverse Correlation with Dementia Severity

European neurology, 1998-01, Vol.39 (2), p.111-118

1998

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Alzheimer beta A4-amyloid protein precursor in immunocompetent cells

The Journal of biological chemistry, 1992-11, Vol.267 (33), p.23950-23956

1992

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Transforming growth factor β mediates increase of mature transmembrane amyloid precursor protein in microglial cells

FEBS letters, 1994-04, Vol.342 (3), p.267-272

1994

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Quantitative changes in the amyloid βA4 precursor protein in Alzheimer cerebrospinal fluid

Neuroscience letters, 1991-03, Vol.124 (1), p.69-73

1991

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An abnormality of plasma amyloid protein precursor in Alzheimer's disease

Annals of neurology, 1992-07, Vol.32 (1), p.57-65

1992

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The amplifying effect of β-amyloid on cellular calcium signalling is reduced in Alzheimerʼs disease

Neuroreport, 1995-05, Vol.6 (8), p.1199-1202

1995

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Synthesis and secretion of Alzheimer amyloid βA4 precursor protein by stimulated human peripheral blood leucocytes

FEBS letters, 1990-12, Vol.277 (1), p.261-266

1990

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In-vitro matured human macrophages express Alzheimer's βA4-amyloid precursor protein indicating synthesis in microglial cells

FEBS letters, 1991-05, Vol.282 (2), p.335-340

1991

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Inhibition of BUB1 Kinase by BAY 1816032 Sensitizes Tumor Cells toward Taxanes, ATR, and PARP Inhibitors In Vitro and In Vivo

Potential and Limits of Kidney Cells for Evaluation of Renal Excretion

Preclinical evaluation of BAY 1075553, a novel super(18)F-labelled inhibitor of prostate-specific membrane antigen for PET imaging of prostate cancer

Gene expression profiling of scrapie-infected brain tissue

Preclinical evaluation of BAY 1075553, a novel 18F-labelled inhibitor of prostate-specific membrane antigen for PET imaging of prostate cancer

Abstract 4851: Second generation 2,3-dihydroimidazo[1,2-c]quinazoline PI3K inhibitors: development of BAY 1082439, a novel balanced PI3Ká / PI3Kâ inhibitor

Abstract 287: BAY 1816032, a novel BUB1 kinase inhibitor with potent antitumor activity

Preclinical evaluation of BAY 1075553, a novel (18)F-labelled inhibitor of prostate-specific membrane antigen for PET imaging of prostate cancer

Abstract 2718: Synthesis and characterization of novel benzylpyrazole-based BUB1 kinase inhibitors with anti-tumor activity

Expression of the APP gene family in brain cells, brain development and aging

Preclinical evaluation of BAY 1075553, a novel ^sup 18^F-labelled inhibitor of prostate-specific membrane antigen for PET imaging of prostate cancer

Mechanisms of amyloid deposition in Alzheimer's disease

Amyloid-like properties of peptides flanking the epitope of amyloid precursor protein-specific monoclonal antibody 22C11

Amyloid precursor protein secretion and βA4 amyloid generation are not mutually exclusive

Identification and differential expression of a novel alternative splice isoform of the beta A4 amyloid precursor protein (APP) mRNA in leukocytes and brain microglial cells

Regulation and Expression of the Alzheimer's β/A4 Amyloid Protein Precursor in Health, Disease, and Down's Syndrome

Extracellular Matrix Influences the Biogenesis of Amyloid Precursor Protein in Microglial Cells (∗)

Cerebrospinal Fluid Levels of Amyloid Precursor Protein and Amyloid β-Peptide in Alzheimer’s Disease and Major Depression – Inverse Correlation with Dementia Severity

Alzheimer beta A4-amyloid protein precursor in immunocompetent cells

Transforming growth factor β mediates increase of mature transmembrane amyloid precursor protein in microglial cells

Quantitative changes in the amyloid βA4 precursor protein in Alzheimer cerebrospinal fluid

An abnormality of plasma amyloid protein precursor in Alzheimer's disease

The amplifying effect of β-amyloid on cellular calcium signalling is reduced in Alzheimerʼs disease

Synthesis and secretion of Alzheimer amyloid βA4 precursor protein by stimulated human peripheral blood leucocytes

In-vitro matured human macrophages express Alzheimer's βA4-amyloid precursor protein indicating synthesis in microglial cells

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