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Protein epitope mimetic macrocycles as biopharmaceuticals

Current opinion in chemical biology, 2017-06, Vol.38, p.45-51

2017

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Chimeric peptidomimetic antibiotics against Gram-negative bacteria

Nature (London), 2019-12, Vol.576 (7787), p.452-458

2019

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Early Molecular Insights into Thanatin Analogues Binding to A. baumannii LptA

Molecules (Basel, Switzerland), 2023-05, Vol.28 (11), p.4335

2023

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A Peptidomimetic Antibiotic Targets Outer Membrane Proteins and Disrupts Selectively the Outer Membrane in Escherichia coli

The Journal of biological chemistry, 2016-01, Vol.291 (4), p.1921-1932

2016

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The design, structures and therapeutic potential of protein epitope mimetics

Drug discovery today, 2008-11, Vol.13 (21), p.944-951

2008

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Discovery of a small molecule ligand of FRS2 that inhibits invasion and tumor growth

Cellular oncology (Dordrecht), 2023-04, Vol.46 (2), p.331-356

2023

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Conformation-Dependent Recognition of HIV gp120 by Designed Ankyrin Repeat Proteins Provides Access to Novel HIV Entry Inhibitors

Journal of Virology, 2013-05, Vol.87 (10), p.5868-5881

2013

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Author Correction: An epitope-specific chemically defined nanoparticle vaccine for respiratory syncytial virus

npj vaccines, 2021-08, Vol.6 (1), p.111-111, Article 111

2021

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Protein Ligand Design: From Phage Display to Synthetic Protein Epitope Mimetics in Human Antibody Fc-Binding Peptidomimetics

Journal of the American Chemical Society, 2006-03, Vol.128 (8), p.2726-2732

2006

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Peptidomimetic inhibitors targeting the CCR5-binding site on the human immunodeficiency virus type-1 gp120 glycoprotein complexed to CD4

Chemical communications (Cambridge, England), 2010-01, Vol.46 (41), p.7754-7756

2010

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Protein Epitope Mimetics: From New Antibiotics to Supramolecular Synthetic Vaccines

Accounts of chemical research, 2017-06, Vol.50 (6), p.1323-1331

2017

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Synthesis and conformational analysis of 18-membered Aib-containing cyclohexapeptides

Tetrahedron, 2005-02, Vol.61 (7), p.1871-1883

2005

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Structural Mimicry of Canonical Conformations in Antibody Hypervariable Loops Using Cyclic Peptides Containing a Heterochiral Diproline Template

Journal of the American Chemical Society, 1999-03, Vol.121 (12), p.2679-2685

1999

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Synthesis and antimicrobial activity against Pseudomonas aeruginosa of macrocyclic β-hairpin peptidomimetic antibiotics containing N-methylated amino acids

Bioorganic & medicinal chemistry, 2016-12, Vol.24 (24), p.6332-6339

2016

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Thanatin targets the intermembrane protein complex required for lipopolysaccharide transport in Escherichia coli

Science advances, 2018-11, Vol.4 (11), p.eaau2634-eaau2634

2018

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A Peptidomimetic Antibiotic Interacts with the Periplasmic Domain of LptD from Pseudomonas aeruginosa

ACS chemical biology, 2018-03, Vol.13 (3), p.666-675

2018

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TBIO-08. The molecular basis for rational targeting of FGFR-driven growth and invasiveness in pediatric brain tumors

Neuro-oncology (Charlottesville, Va.), 2022-06, Vol.24 (Supplement_1), p.i184-i184

2022

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Structural studies of β-hairpin peptidomimetic antibiotics that target LptD in Pseudomonas sp

Bioorganic & medicinal chemistry, 2013-09, Vol.21 (18), p.5806-5810

2013

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β-Hairpin protein epitope mimetic technology in drug discovery

Drug discovery today. Technologies, 2012, Vol.9 (1), p.e63-e69

2012

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Structural aspects of molecular recognition in the immune system. Part II: Pattern recognition receptors (IUPAC Technical Report)

Pure and applied chemistry, 2014-10, Vol.86 (10), p.1483-1538

2014

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Solution Structure and Dynamics of LptE from Pseudomonas aeruginosa

Biochemistry (Easton), 2016-05, Vol.55 (21), p.2936-2943

2016

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Synthetic Virus-Like Particles and Conformationally Constrained Peptidomimetics in Vaccine Design

Chembiochem : a European journal of chemical biology, 2011-12, Vol.12 (18), p.2829-2836

2011

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Structural aspects of molecular recognition in the immune system. Part I: Acquired immunity (IUPAC Technical Report)

Pure and applied chemistry, 2014-10, Vol.86 (10), p.1435-1481

2014

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Synthetic Virus-Like Particles from Self-Assembling Coiled-Coil Lipopeptides and Their Use in Antigen Display to the Immune System

Angewandte Chemie (International ed.), 2007-01, Vol.46 (47), p.9015-9018

2007

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Peptidomimetic antibiotics disrupt the lipopolysaccharide transport bridge of drug-resistant Enterobacteriaceae

Science advances, 2023-05, Vol.9 (21), p.eadg3683

2023

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Protein epitope mimetic macrocycles as biopharmaceuticals

Chimeric peptidomimetic antibiotics against Gram-negative bacteria

Early Molecular Insights into Thanatin Analogues Binding to A. baumannii LptA

A Peptidomimetic Antibiotic Targets Outer Membrane Proteins and Disrupts Selectively the Outer Membrane in Escherichia coli

The design, structures and therapeutic potential of protein epitope mimetics

Discovery of a small molecule ligand of FRS2 that inhibits invasion and tumor growth

Conformation-Dependent Recognition of HIV gp120 by Designed Ankyrin Repeat Proteins Provides Access to Novel HIV Entry Inhibitors

Author Correction: An epitope-specific chemically defined nanoparticle vaccine for respiratory syncytial virus

Protein Ligand Design: From Phage Display to Synthetic Protein Epitope Mimetics in Human Antibody Fc-Binding Peptidomimetics

Peptidomimetic inhibitors targeting the CCR5-binding site on the human immunodeficiency virus type-1 gp120 glycoprotein complexed to CD4

Protein Epitope Mimetics: From New Antibiotics to Supramolecular Synthetic Vaccines

Synthesis and conformational analysis of 18-membered Aib-containing cyclohexapeptides

Structural Mimicry of Canonical Conformations in Antibody Hypervariable Loops Using Cyclic Peptides Containing a Heterochiral Diproline Template

Synthesis and antimicrobial activity against Pseudomonas aeruginosa of macrocyclic β-hairpin peptidomimetic antibiotics containing N-methylated amino acids

Thanatin targets the intermembrane protein complex required for lipopolysaccharide transport in Escherichia coli

A Peptidomimetic Antibiotic Interacts with the Periplasmic Domain of LptD from Pseudomonas aeruginosa

TBIO-08. The molecular basis for rational targeting of FGFR-driven growth and invasiveness in pediatric brain tumors

Structural studies of β-hairpin peptidomimetic antibiotics that target LptD in Pseudomonas sp

β-Hairpin protein epitope mimetic technology in drug discovery

Structural aspects of molecular recognition in the immune system. Part II: Pattern recognition receptors (IUPAC Technical Report)

Solution Structure and Dynamics of LptE from Pseudomonas aeruginosa

Synthetic Virus-Like Particles and Conformationally Constrained Peptidomimetics in Vaccine Design

Structural aspects of molecular recognition in the immune system. Part I: Acquired immunity (IUPAC Technical Report)

Synthetic Virus-Like Particles from Self-Assembling Coiled-Coil Lipopeptides and Their Use in Antigen Display to the Immune System

Peptidomimetic antibiotics disrupt the lipopolysaccharide transport bridge of drug-resistant Enterobacteriaceae

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