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Anthrax Pathogenesis

Annual review of microbiology, 2015-10, Vol.69 (1), p.185-208

2015

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Sulforaphane inhibits multiple inflammasomes through an Nrf2‐independent mechanism

Journal of leukocyte biology, 2016-01, Vol.99 (1), p.189-199

2016

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Rapid induction of inflammatory lipid mediators by the inflammasome in vivo

Nature (London), 2012-10, Vol.490 (7418), p.107-111

2012

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The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes

The Journal of immunology (1950), 2015-03, Vol.194 (6), p.2776-2785

2015

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Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome

PLoS pathogens, 2012-03, Vol.8 (3), p.e1002638-e1002638

2012

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Lysosomal Cathepsin Release Is Required for NLRP3-Inflammasome Activation by Mycobacterium tuberculosis in Infected Macrophages

Frontiers in immunology, 2018-06, Vol.9, p.1427-1427

2018

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Inflammasome sensor NLRP1 controls rat macrophage susceptibility to Toxoplasma gondii

PLoS pathogens, 2014-03, Vol.10 (3), p.e1003927-e1003927

2014

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Hijacking Multivesicular Bodies Enables Long-Term and Exosome-Mediated Long-Distance Action of Anthrax Toxin

Cell reports (Cambridge), 2013-11, Vol.5 (4), p.986-996

2013

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Key tissue targets responsible for anthrax-toxin-induced lethality

Nature (London), 2013-08, Vol.501 (7465), p.63-68

2013

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A Bacteriophage T4 Nanoparticle-Based Dual Vaccine against Anthrax and Plague

mBio, 2018-10, Vol.9 (5)

2018

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Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii

mBio, 2014-02, Vol.5 (1)

2014

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S9.6-based hybrid capture immunoassay for pathogen detection

Scientific reports, 2023-12, Vol.13 (1), p.22562-22562, Article 22562

2023

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Anthrax lethal factor cleaves mouse nlrp1b in both toxin-sensitive and toxin-resistant macrophages

PloS one, 2012-11, Vol.7 (11), p.e49741

2012

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Monoclonal antibody therapies against anthrax

Toxins, 2011-08, Vol.3 (8), p.1004-1019

2011

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Transcriptional analysis of the three Nlrp1 paralogs in mice

BMC genomics, 2013-03, Vol.14 (1), p.188-188

2013

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Characterization of the NLRP1 inflammasome response in bovine species

Innate immunity (London, England), 2020-05, Vol.26 (4), p.301-311

2020

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Arsenic trioxide and other arsenical compounds inhibit the NLRP1, NLRP3, and NAIP5/NLRC4 inflammasomes

The Journal of immunology (1950), 2014-01, Vol.192 (2), p.763-770

2014

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Inflammasome sensor Nlrp1b-dependent resistance to anthrax is mediated by caspase-1, IL-1 signaling and neutrophil recruitment

PLoS pathogens, 2010-12, Vol.6 (12), p.e1001222-e1001222

2010

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Plant-Based Vaccine: Mice Immunized with Chloroplast-Derived Anthrax Protective Antigen Survive Anthrax Lethal Toxin Challenge

Infection and Immunity, 2005-12, Vol.73 (12), p.8266-8274

2005

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Capillary morphogenesis protein-2 is the major receptor mediating lethality of anthrax toxin in vivo

Proceedings of the National Academy of Sciences - PNAS, 2009-07, Vol.106 (30), p.12424-12429

2009

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CA-074Me Protection against Anthrax Lethal Toxin

Infection and Immunity, 2009-10, Vol.77 (10), p.4327-4336

2009

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Mycobacterium tuberculosis Induces Irg1 in Murine Macrophages by a Pathway Involving Both TLR-2 and STING/IFNAR Signaling and Requiring Bacterial Phagocytosis

Frontiers in cellular and infection microbiology, 2022-05, Vol.12, p.862582-862582

2022

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A Review of the Efficacy of FDA-Approved B. anthracis Anti-Toxin Agents When Combined with Antibiotic or Hemodynamic Support in Infection- or Toxin-Challenged Preclinical Models

Toxins, 2021-01, Vol.13 (1), p.53

2021

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Susceptibility to anthrax lethal toxin-induced rat death is controlled by a single chromosome 10 locus that includes rNlrp1

PLoS pathogens, 2010-05, Vol.6 (5), p.e1000906-e1000906

2010

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Anthrax Pathogenesis

Sulforaphane inhibits multiple inflammasomes through an Nrf2‐independent mechanism

Rapid induction of inflammatory lipid mediators by the inflammasome in vivo

The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes

Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome

Lysosomal Cathepsin Release Is Required for NLRP3-Inflammasome Activation by Mycobacterium tuberculosis in Infected Macrophages

Inflammasome sensor NLRP1 controls rat macrophage susceptibility to Toxoplasma gondii

Hijacking Multivesicular Bodies Enables Long-Term and Exosome-Mediated Long-Distance Action of Anthrax Toxin

Key tissue targets responsible for anthrax-toxin-induced lethality

A Bacteriophage T4 Nanoparticle-Based Dual Vaccine against Anthrax and Plague

Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii

S9.6-based hybrid capture immunoassay for pathogen detection

Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2 + DRG sensory neurons

Anthrax lethal factor cleaves mouse nlrp1b in both toxin-sensitive and toxin-resistant macrophages

Monoclonal antibody therapies against anthrax

Transcriptional analysis of the three Nlrp1 paralogs in mice

Characterization of the NLRP1 inflammasome response in bovine species

Arsenic trioxide and other arsenical compounds inhibit the NLRP1, NLRP3, and NAIP5/NLRC4 inflammasomes

Inflammasome sensor Nlrp1b-dependent resistance to anthrax is mediated by caspase-1, IL-1 signaling and neutrophil recruitment

Plant-Based Vaccine: Mice Immunized with Chloroplast-Derived Anthrax Protective Antigen Survive Anthrax Lethal Toxin Challenge

Capillary morphogenesis protein-2 is the major receptor mediating lethality of anthrax toxin in vivo

CA-074Me Protection against Anthrax Lethal Toxin

Mycobacterium tuberculosis Induces Irg1 in Murine Macrophages by a Pathway Involving Both TLR-2 and STING/IFNAR Signaling and Requiring Bacterial Phagocytosis

A Review of the Efficacy of FDA-Approved B. anthracis Anti-Toxin Agents When Combined with Antibiotic or Hemodynamic Support in Infection- or Toxin-Challenged Preclinical Models

Susceptibility to anthrax lethal toxin-induced rat death is controlled by a single chromosome 10 locus that includes rNlrp1

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