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Characterization of SB‐269970‐A, a selective 5‐HT7 receptor antagonist

British journal of pharmacology, 2000-06, Vol.130 (3), p.539-548

2000

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Design and Synthesis of trans-3-(2-(4-((3-(3-(5-Methyl-1,2,4-oxadiazolyl))- phenyl)carboxamido)cyclohexyl)ethyl)-7-methylsulfonyl-2,3,4,5-tetrahydro- 1H-3-benzazepine (SB-414796): A Potent and Selective Dopamine D3 Receptor Antagonist

Journal of medicinal chemistry, 2003-11, Vol.46 (23), p.4952-4964

2003

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Dopamine D3 Receptor Antagonism Inhibits Cocaine-Seeking and Cocaine-Enhanced Brain Reward in Rats

The Journal of neuroscience, 2002-11, Vol.22 (21), p.9595-9603

2002

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Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/ serotonin reuptake inhibitor, vilazodone

European journal of pharmacology, 2005-03, Vol.510 (1-2), p.49-57

2005

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Functional comparison of muscarinic partial agonists at muscarinic receptor subtypes hM1, hM2, hM3, hM4 and hM5 using microphysiometry

British journal of pharmacology, 1999-04, Vol.126 (7), p.1620-1624

1999

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Quantitative mRNA analysis of five C-terminal splice variants of the human 5-HT4 receptor in the central nervous system by TaqMan real time RT-PCR

Brain research. Molecular brain research., 2001-06, Vol.90 (2), p.125-134

2001

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SB‐656104‐A, a novel selective 5‐HT7 receptor antagonist, modulates REM sleep in rats

British journal of pharmacology, 2003-06, Vol.139 (4), p.705-714

2003

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Characterization of SB‐271046: A potent, selective and orally active 5‐HT6 receptor antagonist

British journal of pharmacology, 2000-08, Vol.130 (7), p.1606-1612

2000

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Serotonergic targets in depression

Current Opinion in Pharmacology, 2002-02, Vol.2 (1), p.18-22

2002

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Characterization of [125I]‐SB‐258585 binding to human recombinant and native 5‐HT6 receptors in rat, pig and human brain tissue

British journal of pharmacology, 2000-08, Vol.130 (7), p.1597-1605

2000

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Pharmacological characterisation of human 5-HT2 receptor subtypes

European journal of pharmacology, 2001-02, Vol.414 (1), p.23-30

2001

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Cannabinoid activation of recombinant and endogenous vanilloid receptors

European journal of pharmacology, 2001-07, Vol.424 (3), p.211-219

2001

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3,4-Dihydro-2H-benzoxazinones are 5-HT1A receptor antagonists with potent 5-HT reuptake inhibitory activity

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (3), p.737-741

2005

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Ligands for the investigation of 5-HT autoreceptor function

Brain research bulletin, 2001-11, Vol.56 (5), p.463-469

2001

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Functional characterisation of the human cloned 5‐HT7 receptor (long form); antagonist profile of SB‐258719

British journal of pharmacology, 1998-07, Vol.124 (6), p.1300-1306

1998

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Design and Synthesis of trans-N-[4-[2-(6-Cyano-1,2,3,4-tetrahydroisoquinolin-2- yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011): A Potent and Selective Dopamine D3 Receptor Antagonist with High Oral Bioavailability and CNS Penetration in the Rat

Journal of medicinal chemistry, 2000-05, Vol.43 (9), p.1878-1885

2000

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(R)-3,N-Dimethyl-N-[1-methyl-3-(4-methylpiperidin-1-yl)propyl]benzenesulfonamide: The First Selective 5-HT7 Receptor Antagonist

Journal of medicinal chemistry, 1998-02, Vol.41 (5), p.655-657

1998

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[3H]‐SB‐269970 – A selective antagonist radioligand for 5‐HT7 receptors

British journal of pharmacology, 2000-05, Vol.130 (2), p.409-417

2000

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The putative 5-HT1 receptor agonist, RU 24969, inhibits the efflux of 5-hydroxytryptamine from rat frontal cortex slices by stimulation of the 5-HT autoreceptor

Journal of pharmacy and pharmacology, 1985-06, Vol.37 (6), p.434-437

Middlemiss, Derek N.

1985

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Parkinson's disease: prospects for improved drug therapy

Trends in pharmacological sciences (Regular ed.), 1997-05, Vol.18 (5), p.156-163

1997

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The effect of SB‐269970, a 5‐HT7 receptor antagonist, on 5‐HT release from serotonergic terminals and cell bodies

British journal of pharmacology, 2001-04, Vol.132 (7), p.1574-1580

2001

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Comparison of the functional potencies of ropinirole and other dopamine receptor agonists at human D 2(long) , D 3 and D 4.4 receptors expressed in Chinese hamster ovary cells

British journal of pharmacology, 2009-01, Vol.127 (7), p.1696-1702

2009

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Effect of acute and chronic administration of the selective 5-HT2C receptor antagonist SB-243213 on midbrain dopamine neurons in the rat: An in vivo extracellular single cell study

Synapse (New York, N.Y.), 2002-12, Vol.46 (3), p.129-139

2002

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Centrally active 5-HT receptor agonists and antagonists

Neuroscience and biobehavioral reviews, 1992, Vol.16 (1), p.75-82

1992

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Characterization of SB‐269970‐A, a selective 5‐HT7 receptor antagonist

Design and Synthesis of trans-3-(2-(4-((3-(3-(5-Methyl-1,2,4-oxadiazolyl))- phenyl)carboxamido)cyclohexyl)ethyl)-7-methylsulfonyl-2,3,4,5-tetrahydro- 1H-3-benzazepine (SB-414796): A Potent and Selective Dopamine D3 Receptor Antagonist

Dopamine D3 Receptor Antagonism Inhibits Cocaine-Seeking and Cocaine-Enhanced Brain Reward in Rats

Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/ serotonin reuptake inhibitor, vilazodone

Functional comparison of muscarinic partial agonists at muscarinic receptor subtypes hM1, hM2, hM3, hM4 and hM5 using microphysiometry

Quantitative mRNA analysis of five C-terminal splice variants of the human 5-HT4 receptor in the central nervous system by TaqMan real time RT-PCR

SB‐656104‐A, a novel selective 5‐HT7 receptor antagonist, modulates REM sleep in rats

Characterization of SB‐271046: A potent, selective and orally active 5‐HT6 receptor antagonist

Serotonergic targets in depression

Characterization of [125I]‐SB‐258585 binding to human recombinant and native 5‐HT6 receptors in rat, pig and human brain tissue

Pharmacological characterisation of human 5-HT2 receptor subtypes

Cannabinoid activation of recombinant and endogenous vanilloid receptors

3,4-Dihydro-2H-benzoxazinones are 5-HT1A receptor antagonists with potent 5-HT reuptake inhibitory activity

Ligands for the investigation of 5-HT autoreceptor function

Functional characterisation of the human cloned 5‐HT7 receptor (long form); antagonist profile of SB‐258719

Design and Synthesis of trans-N-[4-[2-(6-Cyano-1,2,3,4-tetrahydroisoquinolin-2- yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011): A Potent and Selective Dopamine D3 Receptor Antagonist with High Oral Bioavailability and CNS Penetration in the Rat

(R)-3,N-Dimethyl-N-[1-methyl-3-(4-methylpiperidin-1-yl)propyl]benzenesulfonamide: The First Selective 5-HT7 Receptor Antagonist

[3H]‐SB‐269970 – A selective antagonist radioligand for 5‐HT7 receptors

The putative 5-HT1 receptor agonist, RU 24969, inhibits the efflux of 5-hydroxytryptamine from rat frontal cortex slices by stimulation of the 5-HT autoreceptor

Parkinson's disease: prospects for improved drug therapy

Biarylcarbamoylindolines Are Novel and Selective 5-HT2C Receptor Inverse Agonists: Identification of 5-Methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]- 5-pyridyl]carbamoyl]-6-trifluoromethylindoline (SB-243213) as a Potential Antidepressant/Anxiolytic Agent

The effect of SB‐269970, a 5‐HT7 receptor antagonist, on 5‐HT release from serotonergic terminals and cell bodies

Comparison of the functional potencies of ropinirole and other dopamine receptor agonists at human D 2(long) , D 3 and D 4.4 receptors expressed in Chinese hamster ovary cells

Effect of acute and chronic administration of the selective 5-HT2C receptor antagonist SB-243213 on midbrain dopamine neurons in the rat: An in vivo extracellular single cell study

Centrally active 5-HT receptor agonists and antagonists

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