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Systems pharmacology and drug repositioning- an integrated approach to metabolic diseases

Journal of translational medicine, 2012-10, Vol.10 (S2), p.A18-A18, Article A18

Luther, Michael A

2012

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Crystal Structures of Recombinant 19-kDa Human Fibroblast Collagenase Complexed to Itself

Biochemistry (Easton), 1994-07, Vol.33 (27), p.8207-8217

1994

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Atomic Structure of PDE4: Insights into Phosphodiesterase Mechanism and Specificity

Science (American Association for the Advancement of Science), 2000-06, Vol.288 (5472), p.1822-1825

2000

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Crystal Structures of the Catalytic Domain of Phosphodiesterase 4B Complexed with AMP, 8-Br-AMP, and Rolipram

Journal of molecular biology, 2004-03, Vol.337 (2), p.355-365

2004

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Phorbol Esters and SDF-1 Induce Rapid Endocytosis and down Modulation of the Chemokine Receptor CXCR4

The Journal of cell biology, 1997-11, Vol.139 (3), p.651-664

1997

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Structure of the Catalytic Domain of Fibroblast Collagenase Complexed with an Inhibitor

Science (American Association for the Advancement of Science), 1994-01, Vol.263 (5145), p.375-377

1994

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Human Recombinant Phosphodiesterase 4B2B Binds (R)-Rolipram at a Single Site with Two Affinities

Biochemistry (Easton), 1997-11, Vol.36 (46), p.14250-14261

1997

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Thermodynamics of dimer and tetramer formations in rabbit muscle phosphofructokinase

Biochemistry (Easton), 1986-12, Vol.25 (24), p.7931-7937

1986

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Detailed Characterization of a Purified Type 4 Phosphodiesterase, HSPDE4B2B: Differentiation of High- and Low-Affinity (R)-Rolipram Binding

Protein expression and purification, 1997-03, Vol.9 (2), p.191-202

1997

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Dual Inhibition of Human Type 4 Phosphodiesterase Isostates by (R,R)-(±)-Methyl 3-Acetyl-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-3- methyl-1-pyrrolidinecarboxylate

Biochemistry (Easton), 1998-05, Vol.37 (19), p.6894-6904

1998

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Subunit interaction of rabbit muscle phosphofructokinase: effects of purification procedures

Biochemistry (Easton), 1985-05, Vol.24 (10), p.2463-2470

1985

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Agouti structure and function: characterization of a potent .alpha.-melanocyte stimulating hormone receptor antagonist

Biochemistry (Easton), 1995-09, Vol.34 (38), p.12341-12346

1995

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Self-association of rabbit muscle phosphofructokinase: role of subunit interaction in regulation of enzymic activity

Biochemistry (Easton), 1983-11, Vol.22 (24), p.5494-5500

1983

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A Soluble, Single-Chain T-Cell Receptor Fragment Endowed with Antigen-Combining Properties

Proceedings of the National Academy of Sciences - PNAS, 1991-10, Vol.88 (19), p.8646-8650

1991

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N-glycosylation is required for human CD2 immunoadhesion functions

The Journal of biological chemistry, 1992-11, Vol.267 (31), p.22428-22434

1992

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Regulation of rabbit muscle phosphofructokinase by phosphorylation

Biophysical chemistry, 1997-02, Vol.64 (1), p.199-209

1997

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Rapid, two-step purification process for the preparation of pyrogen-free murine immunoglobulin G1 monoclonal antibodies

Journal of Chromatography A, 1992-01, Vol.590 (2), p.255-261

1992

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Exploration of the Sequence Specificity of pp60c-src Tyrosine Kinase

The Journal of biological chemistry, 1995-11, Vol.270 (45), p.27112-27115

1995

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Exploration of the Sequence Specificity of pp60 Tyrosine Kinase

The Journal of biological chemistry, 1995-11, Vol.270 (45), p.27112

1995

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Exploration of the Sequence Specificity of pp60c- Tyrosine Kinase

The Journal of biological chemistry, 1995-11, Vol.270 (45), p.27112-27115

1995

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Structural Analysis of the Catalytic Domain of Human Fibroblast Collagenase

Annals of the New York Academy of Sciences, 1994-09, Vol.732 (1), p.375-378

1994

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Rapid, two-step purification process for the preparation of pyrogen-free murine immunoglobulin G 1 monoclonal antibodies

Journal of Chromatography A, 1992, Vol.590 (2), p.255-261

1992

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Preliminary X-ray diffraction studies of recombinant 19 kDa human fibroblast collagenase

Journal of molecular biology, 1994-03, Vol.236 (5), p.1410-1412

1994

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Inhibition of T Cell Activation and Adhesion Functions by Soluble CD2 Protein

Cellular immunology, 1993-06, Vol.149 (1), p.24-38

1993

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Regulation and quaternary structural changes in rabbit muscle phosphofructokinase

Biophysical chemistry, 1990-08, Vol.37 (1), p.97-106

1990

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Systems pharmacology and drug repositioning- an integrated approach to metabolic diseases

Crystal Structures of Recombinant 19-kDa Human Fibroblast Collagenase Complexed to Itself

Atomic Structure of PDE4: Insights into Phosphodiesterase Mechanism and Specificity

Crystal Structures of the Catalytic Domain of Phosphodiesterase 4B Complexed with AMP, 8-Br-AMP, and Rolipram

Phorbol Esters and SDF-1 Induce Rapid Endocytosis and down Modulation of the Chemokine Receptor CXCR4

Structure of the Catalytic Domain of Fibroblast Collagenase Complexed with an Inhibitor

Human Recombinant Phosphodiesterase 4B2B Binds (R)-Rolipram at a Single Site with Two Affinities

Thermodynamics of dimer and tetramer formations in rabbit muscle phosphofructokinase

Detailed Characterization of a Purified Type 4 Phosphodiesterase, HSPDE4B2B: Differentiation of High- and Low-Affinity (R)-Rolipram Binding

Dual Inhibition of Human Type 4 Phosphodiesterase Isostates by (R,R)-(±)-Methyl 3-Acetyl-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-3- methyl-1-pyrrolidinecarboxylate

Subunit interaction of rabbit muscle phosphofructokinase: effects of purification procedures

Agouti structure and function: characterization of a potent .alpha.-melanocyte stimulating hormone receptor antagonist

Self-association of rabbit muscle phosphofructokinase: role of subunit interaction in regulation of enzymic activity

A Soluble, Single-Chain T-Cell Receptor Fragment Endowed with Antigen-Combining Properties

N-glycosylation is required for human CD2 immunoadhesion functions

Regulation of rabbit muscle phosphofructokinase by phosphorylation

Rapid, two-step purification process for the preparation of pyrogen-free murine immunoglobulin G1 monoclonal antibodies

Exploration of the Sequence Specificity of pp60c-src Tyrosine Kinase

Exploration of the Sequence Specificity of pp60 Tyrosine Kinase

Exploration of the Sequence Specificity of pp60c- Tyrosine Kinase

Structural Analysis of the Catalytic Domain of Human Fibroblast Collagenase

Rapid, two-step purification process for the preparation of pyrogen-free murine immunoglobulin G 1 monoclonal antibodies

Preliminary X-ray diffraction studies of recombinant 19 kDa human fibroblast collagenase

Inhibition of T Cell Activation and Adhesion Functions by Soluble CD2 Protein

Regulation and quaternary structural changes in rabbit muscle phosphofructokinase

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