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SLiM 3: Forward Genetic Simulations Beyond the Wright–Fisher Model

Molecular biology and evolution, 2019-03, Vol.36 (3), p.632-637

2019

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Recent selective sweeps in North American Drosophila melanogaster show signatures of soft sweeps

PLoS genetics, 2015-02, Vol.11 (2), p.e1005004-e1005004

2015

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SLiM: simulating evolution with selection and linkage

Genetics (Austin), 2013-08, Vol.194 (4), p.1037-1039

Messer, Philipp W

2013

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Population genomics of rapid adaptation by soft selective sweeps

Trends in ecology & evolution (Amsterdam), 2013-11, Vol.28 (11), p.659-669

2013

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Novel CRISPR/Cas9 gene drive constructs reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations

PLoS genetics, 2017-07, Vol.13 (7), p.e1006796-e1006796

2017

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SLiM 4: Multispecies Eco-Evolutionary Modeling

The American naturalist, 2023-05, Vol.201 (5), p.E127-E139

2023

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Strong purifying selection at synonymous sites in D. melanogaster

PLoS genetics, 2013-05, Vol.9 (5), p.e1003527

2013

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SLiM 2: Flexible, Interactive Forward Genetic Simulations

Molecular biology and evolution, 2017-01, Vol.34 (1), p.230-240

2017

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Detection of hard and soft selective sweeps from Drosophila melanogaster population genomic data

PLoS genetics, 2021-02, Vol.17 (2), p.e1009373-e1009373

2021

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Evolution of Resistance Against CRISPR/Cas9 Gene Drive

Genetics (Austin), 2017-02, Vol.205 (2), p.827-841

2017

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Plumage Genes and Little Else Distinguish the Genomes of Hybridizing Warblers

Current biology, 2016-09, Vol.26 (17), p.2313-2318

2016

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Frequent adaptation and the McDonald–Kreitman test

Proceedings of the National Academy of Sciences - PNAS, 2013-05, Vol.110 (21), p.8615-8620

2013

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Evidence that adaptation in Drosophila is not limited by mutation at single sites

PLoS genetics, 2010-05, Vol.6 (6), p.e1000924-e1000924

2010

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A toxin-antidote CRISPR gene drive system for regional population modification

Nature communications, 2020-02, Vol.11 (1), p.1082-10, Article 1082

2020

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A CRISPR homing gene drive targeting a haplolethal gene removes resistance alleles and successfully spreads through a cage population

Proceedings of the National Academy of Sciences - PNAS, 2020-09, Vol.117 (39), p.24377-24383

2020

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Reducing resistance allele formation in CRISPR gene drive

Proceedings of the National Academy of Sciences - PNAS, 2018-05, Vol.115 (21), p.5522-5527

2018

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Can Population Genetics Adapt to Rapid Evolution?

Trends in genetics, 2016-07, Vol.32 (7), p.408-418

2016

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Genome-wide signals of positive selection in human evolution

Genome research, 2014-06, Vol.24 (6), p.885-895

2014

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Genome patterns of selection and introgression of haplotypes in natural populations of the house mouse (Mus musculus)

PLoS genetics, 2012-08, Vol.8 (8), p.e1002891-e1002891

2012

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Tree‐sequence recording in SLiM opens new horizons for forward‐time simulation of whole genomes

Molecular ecology resources, 2019-03, Vol.19 (2), p.552-566

2019

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Modeling CRISPR gene drives for suppression of invasive rodents using a supervised machine learning framework

PLoS computational biology, 2021-12, Vol.17 (12), p.e1009660-e1009660

2021

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Narrow thermal tolerance and low dispersal drive higher speciation in tropical mountains

Proceedings of the National Academy of Sciences - PNAS, 2018-12, Vol.115 (49), p.12471-12476

2018

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Suppression gene drive in continuous space can result in unstable persistence of both drive and wild‐type alleles

Molecular ecology, 2021-02, Vol.30 (4), p.1086-1101

2021

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Evolution under a model of functionally buffered deleterious mutations can lead to positive selection in protein-coding genes

Evolution, 2023-10, Vol.77 (10), p.2200-2212

2023

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Performance analysis of novel toxin-antidote CRISPR gene drive systems

BMC biology, 2020-03, Vol.18 (1), p.27-27, Article 27

2020

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SLiM 3: Forward Genetic Simulations Beyond the Wright–Fisher Model

Recent selective sweeps in North American Drosophila melanogaster show signatures of soft sweeps

SLiM: simulating evolution with selection and linkage

Population genomics of rapid adaptation by soft selective sweeps

Novel CRISPR/Cas9 gene drive constructs reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations

SLiM 4: Multispecies Eco-Evolutionary Modeling

Strong purifying selection at synonymous sites in D. melanogaster

SLiM 2: Flexible, Interactive Forward Genetic Simulations

Detection of hard and soft selective sweeps from Drosophila melanogaster population genomic data

Evolution of Resistance Against CRISPR/Cas9 Gene Drive

Plumage Genes and Little Else Distinguish the Genomes of Hybridizing Warblers

Frequent adaptation and the McDonald–Kreitman test

Evidence that adaptation in Drosophila is not limited by mutation at single sites

A toxin-antidote CRISPR gene drive system for regional population modification

A CRISPR homing gene drive targeting a haplolethal gene removes resistance alleles and successfully spreads through a cage population

Reducing resistance allele formation in CRISPR gene drive

Can Population Genetics Adapt to Rapid Evolution?

Genome-wide signals of positive selection in human evolution

Genome patterns of selection and introgression of haplotypes in natural populations of the house mouse (Mus musculus)

Tree‐sequence recording in SLiM opens new horizons for forward‐time simulation of whole genomes

Modeling CRISPR gene drives for suppression of invasive rodents using a supervised machine learning framework

Narrow thermal tolerance and low dispersal drive higher speciation in tropical mountains

Suppression gene drive in continuous space can result in unstable persistence of both drive and wild‐type alleles

Evolution under a model of functionally buffered deleterious mutations can lead to positive selection in protein-coding genes

Performance analysis of novel toxin-antidote CRISPR gene drive systems

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