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Are Metformin Doses Used in Murine Cancer Models Clinically Relevant?

Cell metabolism, 2016-04, Vol.23 (4), p.569-570

2016

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Identification of the Highly Active, Species Cross-Reactive Complex I Inhibitor BAY-179

ACS medicinal chemistry letters, 2022-03, Vol.13 (3), p.348-357

2022

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Drug-class specific impact of antivirals on the reproductive capacity of HIV

PLoS computational biology, 2010-03, Vol.6 (3), p.e1000720-e1000720

2010

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Estimating HIV-1 fitness characteristics from cross-sectional genotype data

PLoS computational biology, 2014-11, Vol.10 (11), p.e1003886-e1003886

2014

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HIV quasispecies dynamics during pro-active treatment switching: impact on multi-drug resistance and resistance archiving in latent reservoirs

PloS one, 2011-03, Vol.6 (3), p.e18204-e18204

2011

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Prediction of Oral Bioavailability in Rats: Transferring Insights from in Vitro Correlations to (Deep) Machine Learning Models Using in Silico Model Outputs and Chemical Structure Parameters

Journal of chemical information and modeling, 2019-11, Vol.59 (11), p.4893-4905

2019

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Prediction of Human Pharmacokinetics From Chemical Structure: Combining Mechanistic Modeling with Machine Learning

Journal of pharmaceutical sciences, 2024-01, Vol.113 (1), p.55-63

2024

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A deep neural network: mechanistic hybrid model to predict pharmacokinetics in rat

Journal of computer-aided molecular design, 2024-12, Vol.38 (1), p.7-7, Article 7

2024

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Binding Kinetics Survey of the Drugged Kinome

Journal of the American Chemical Society, 2018-11, Vol.140 (46), p.15774-15782

2018

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sOAR: a tool for modelling optimal animal life‐history strategies in cyclic environments

Ecography (Copenhagen), 2018-03, Vol.41 (3), p.551-557

2018

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Abstract 3248: Identification and optimization of a highly active, cross reactive Complex-1 inhibitor

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.3248-3248

2017

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Estimating HIV-1 Fitness Characteristics from Cross-Sectional Genotype Data: e1003886

PLoS computational biology, 2014-11, Vol.10 (11)

2014

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Abstract 1126: Differential effects of metformin and phenformin vs. other complex 1 inhibitors in vitro and in vivo

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.1126-1126

2015

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Abstract 223: Comparison of human-specific versus cross-reactive Complex I inhibitor for in vivo tumor efficacy

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.223-223

2016

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Abstract 506: ANJ810 is a highly selective novel MCL1 inhibitor with optimized in vivo clearance showing robust efficacy in preclinical solid and hematological tumor models

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.506-506

2023

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Hybrid Stochastic--Deterministic Solution of the Chemical Master Equation

Multiscale modeling & simulation, 2012-01, Vol.10 (4), p.1232-1262

2012

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Drug-Class Specific Impact of Antivirals on the Reproductive Capacity of HIV: e1000720

PLoS computational biology, 2010-03, Vol.6 (3)

2010

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Quantifying the degree of persistence in random amoeboid motion based on the Hurst exponent of fractional Brownian motion

Physical review. E, Statistical, nonlinear, and soft matter physics, 2014-10, Vol.90 (4), p.042703-042703, Article 042703

2014

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The effectiveness of different policy regimes for promoting wind power: Experiences from the states

Energy policy, 2006-09, Vol.34 (14), p.1786-1796

2006

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The role of social, political, and economic interests in promoting state green electricity policies

Environmental science & policy, 2006-11, Vol.9 (7), p.652-662

2006

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Cardiorespiratory and Metabolic Responses During Graded Exercise in Normobaric and Hypobaric Hypoxia

High altitude medicine & biology, 2020-03, Vol.21 (1), p.70-75

2020

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A Novel Approach to Generate Hourly Photovoltaic Power Scenarios

Sustainability, 2022-04, Vol.14 (8), p.4617

2022

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Aus der Praxis: Spielen als konkrete Methode. Zwei Praxisbeispiele aus den Bereichen Kommunikation, Sprache und sozial-emotionale Frühförderung

Frühförderung interdisziplinär, 2020-03, Vol.39 (2), p.97-105

2020

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Are Metformin Doses Used in Murine Cancer Models Clinically Relevant?

Identification of the Highly Active, Species Cross-Reactive Complex I Inhibitor BAY-179

Drug-class specific impact of antivirals on the reproductive capacity of HIV

Estimating HIV-1 fitness characteristics from cross-sectional genotype data

HIV quasispecies dynamics during pro-active treatment switching: impact on multi-drug resistance and resistance archiving in latent reservoirs

Prediction of Oral Bioavailability in Rats: Transferring Insights from in Vitro Correlations to (Deep) Machine Learning Models Using in Silico Model Outputs and Chemical Structure Parameters

Prediction of Human Pharmacokinetics From Chemical Structure: Combining Mechanistic Modeling with Machine Learning

A deep neural network: mechanistic hybrid model to predict pharmacokinetics in rat

Binding Kinetics Survey of the Drugged Kinome

sOAR: a tool for modelling optimal animal life‐history strategies in cyclic environments

Abstract 3248: Identification and optimization of a highly active, cross reactive Complex-1 inhibitor

Estimating HIV-1 Fitness Characteristics from Cross-Sectional Genotype Data: e1003886

Abstract 1126: Differential effects of metformin and phenformin vs. other complex 1 inhibitors in vitro and in vivo

Abstract 223: Comparison of human-specific versus cross-reactive Complex I inhibitor for in vivo tumor efficacy

BRD-810 is a highly selective MCL1 inhibitor with optimized in vivo clearance and robust efficacy in solid and hematological tumor models

Abstract 506: ANJ810 is a highly selective novel MCL1 inhibitor with optimized in vivo clearance showing robust efficacy in preclinical solid and hematological tumor models

Hybrid Stochastic--Deterministic Solution of the Chemical Master Equation

Drug-Class Specific Impact of Antivirals on the Reproductive Capacity of HIV: e1000720

Quantifying the degree of persistence in random amoeboid motion based on the Hurst exponent of fractional Brownian motion

The effectiveness of different policy regimes for promoting wind power: Experiences from the states

The role of social, political, and economic interests in promoting state green electricity policies

Cardiorespiratory and Metabolic Responses During Graded Exercise in Normobaric and Hypobaric Hypoxia

A Novel Approach to Generate Hourly Photovoltaic Power Scenarios

Elevated MUC5AC expression is associated with mismatch repair deficiency and proximal tumor location but not with cancer progression in colon cancer

Aus der Praxis: Spielen als konkrete Methode. Zwei Praxisbeispiele aus den Bereichen Kommunikation, Sprache und sozial-emotionale Frühförderung

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