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A novel CDK9 inhibitor shows potent antitumor efficacy in preclinical hematologic tumor models

Molecular cancer therapeutics, 2014-06, Vol.13 (6), p.1442-1456

2014

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Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells: metabolic basis and potential clinical implications

The Journal of biological chemistry, 2013-02, Vol.288 (5), p.3500-3511

2013

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BOCILLIN FL, a Sensitive and Commercially Available Reagent for Detection of Penicillin-Binding Proteins

Antimicrobial Agents and Chemotherapy, 1999-05, Vol.43 (5), p.1124-1128

1999

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Identification and characterization of an inhibitor specific to bacterial NAD⁺-dependent DNA ligases

The FEBS journal, 2008-11, Vol.275 (21), p.5258-5271

2008

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Discovery of N‑(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)‑3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Cancer Xenograft Model

Journal of medicinal chemistry, 2017-12, Vol.60 (23), p.9599-9616

2017

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The development of potent and selective bisarylmaleimide GSK3 inhibitors

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (4), p.899-903

2005

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Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models

Scientific reports, 2018-10, Vol.8 (1), p.15458-12, Article 15458

2018

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Development of a fluorescence resonance energy transfer assay for measuring the activity of Streptococcus pneumoniae DNA ligase, an enzyme essential for DNA replication, repair, and recombination

Analytical biochemistry, 2002-10, Vol.309 (2), p.232-240

2002

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Era GTPase of Escherichia coli: binding to 16S rRNA and modulation of GTPase activity by RNA and carbohydrates

Microbiology (Society for General Microbiology), 2000-05, Vol.146 ( Pt 5), p.1071

2000

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Identification and Characterization of the Penicillin-Binding Protein 2a of Streptococcus pneumoniae and Its Possible Role in Resistance to β-Lactam Antibiotics

Antimicrobial Agents and Chemotherapy, 2000-06, Vol.44 (6), p.1745-1748

2000

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Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, in Human Cancer Cells

The Journal of biological chemistry, 2013-02, Vol.288 (5), p.3500-3511

2013

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Transcriptional Pausing at +62 of the HIV-1 Nascent RNA Modulates Formation of the TAR RNA Structure

Molecular cell, 1998-06, Vol.1 (7), p.1033-1042

1998

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Cloning, expression, purification, and characterization of the human Class Ia phosphoinositide 3-kinase isoforms

Protein expression and purification, 2004-06, Vol.35 (2), p.218-224

2004

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Discontinuous movements of DNA and RNA in RNA polymerase accompany formation of a paused transcription complex

Cell, 1995-05, Vol.81 (3), p.341-350

1995

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Gene Disruption Studies of Penicillin-Binding Proteins 1a, 1b, and 2a in Streptococcus pneumoniae

Journal of Bacteriology, 1999-10, Vol.181 (20), p.6552-6555

1999

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Biochemical and Molecular Analyses of the Streptococcus pneumoniae Acyl Carrier Protein Synthase, an Enzyme Essential for Fatty Acid Biosynthesis

The Journal of biological chemistry, 2000-10, Vol.275 (40), p.30864-30872

2000

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16S rRNA is bound to era of Streptococcus pneumoniae

Journal of bacteriology, 1999-09, Vol.181 (17), p.5242-5249

1999

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Biochemical and molecular analyses of the C-terminal domain of Era GTPase from Streptococcus pneumoniae

Microbiology (Society for General Microbiology), 1999-04, Vol.145 ( Pt 4), p.791

1999

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Fluorescent Bocillins: Synthesis and application in the detection of penicillin-binding proteins

Electrophoresis, 2001-04, Vol.22 (5), p.960-965

2001

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Identification and characterization of an inhibitor specific to bacterial NAD super(+)-dependent DNA ligases

European journal of biochemistry, 2008-11, Vol.275 (21), p.5258-5271

2008

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16S rRNA Is Bound to Era ofStreptococcus pneumoniae

Journal of Bacteriology, 1999-09, Vol.181 (17), p.5242

1999

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Analysis of the interaction of 16S rRNA and cytoplasmic membrane with the C‐terminal part of the Streptococcus pneumoniae Era GTPase

European journal of biochemistry, 2001-11, Vol.268 (21), p.5570-5577

2001

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Penicillin-Binding Protein 2a of Streptococcus pneumoniae: Expression in Escherichia coli and Purification and Refolding of Inclusion Bodies into a Soluble and Enzymatically Active Enzyme

Protein expression and purification, 1999-07, Vol.16 (2), p.331-339

1999

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The effect of scan length on the reliability of resting-state fMRI connectivity estimates

NeuroImage (Orlando, Fla.), 2013-12, Vol.83, p.550-558

2013

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The Kynurenine Pathway in Traumatic Brain Injury: Implications for Psychiatric Outcomes

Biological psychiatry (1969), 2022-03, Vol.91 (5), p.449-458

2022

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A novel CDK9 inhibitor shows potent antitumor efficacy in preclinical hematologic tumor models

Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells: metabolic basis and potential clinical implications

BOCILLIN FL, a Sensitive and Commercially Available Reagent for Detection of Penicillin-Binding Proteins

Identification and characterization of an inhibitor specific to bacterial NAD⁺-dependent DNA ligases

The development of potent and selective bisarylmaleimide GSK3 inhibitors

Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models

Development of a fluorescence resonance energy transfer assay for measuring the activity of Streptococcus pneumoniae DNA ligase, an enzyme essential for DNA replication, repair, and recombination

Era GTPase of Escherichia coli: binding to 16S rRNA and modulation of GTPase activity by RNA and carbohydrates

Identification and Characterization of the Penicillin-Binding Protein 2a of Streptococcus pneumoniae and Its Possible Role in Resistance to β-Lactam Antibiotics

Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, in Human Cancer Cells

Transcriptional Pausing at +62 of the HIV-1 Nascent RNA Modulates Formation of the TAR RNA Structure

Cloning, expression, purification, and characterization of the human Class Ia phosphoinositide 3-kinase isoforms

Discontinuous movements of DNA and RNA in RNA polymerase accompany formation of a paused transcription complex

Gene Disruption Studies of Penicillin-Binding Proteins 1a, 1b, and 2a in Streptococcus pneumoniae

Biochemical and Molecular Analyses of the Streptococcus pneumoniae Acyl Carrier Protein Synthase, an Enzyme Essential for Fatty Acid Biosynthesis

16S rRNA is bound to era of Streptococcus pneumoniae

Biochemical and molecular analyses of the C-terminal domain of Era GTPase from Streptococcus pneumoniae

Fluorescent Bocillins: Synthesis and application in the detection of penicillin-binding proteins

Identification and characterization of an inhibitor specific to bacterial NAD super(+)-dependent DNA ligases

16S rRNA Is Bound to Era ofStreptococcus pneumoniae

Analysis of the interaction of 16S rRNA and cytoplasmic membrane with the C‐terminal part of the Streptococcus pneumoniae Era GTPase

Penicillin-Binding Protein 2a of Streptococcus pneumoniae: Expression in Escherichia coli and Purification and Refolding of Inclusion Bodies into a Soluble and Enzymatically Active Enzyme

The effect of scan length on the reliability of resting-state fMRI connectivity estimates

The Kynurenine Pathway in Traumatic Brain Injury: Implications for Psychiatric Outcomes

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