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RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction

Nature communications, 2020-08, Vol.11 (1), p.4305-4305, Article 4305

2020

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Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy

Nature communications, 2023-04, Vol.14 (1), p.2367-16, Article 2367

2023

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Internalization mechanisms of brain-derived tau oligomers from patients with Alzheimer's disease, progressive supranuclear palsy and dementia with Lewy bodies

Cell death & disease, 2020-05, Vol.11 (5), p.314, Article 314

2020

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TDP-43 and Tau Oligomers in Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia

Neurobiology of disease, 2020-12, Vol.146, p.105130-105130, Article 105130

2020

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Tau Modulates mRNA Transcription, Alternative Polyadenylation Profiles of hnRNPs, Chromatin Remodeling and Spliceosome Complexes

Frontiers in molecular neuroscience, 2021-12, Vol.14, p.742790-742790

2021

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Formation of Toxic Oligomeric Assemblies of RNA-binding Protein: Musashi in Alzheimer's disease

Acta neuropathologica communications, 2018-10, Vol.6 (1), p.113-14, Article 113

2018

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Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer’s disease and frontotemporal dementia

Cell reports (Cambridge), 2021-07, Vol.36 (3), p.109419-109419, Article 109419

2021

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TAU OLIGOMERS MEDIATE AGGREGATION OF RNA-BINDING PROTEINS MUSASHI1- AND MUSASHI2-INDUCING NUCLEAR MEMBRANE ALTERATION IN ALZHEIMER’S DISEASE

Alzheimer's & dementia, 2019-07, Vol.15 (7), p.P1513-P1513

2019

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P4‐520: TAU OLIGOMERS MEDIATE AGGREGATION OF RNA‐BINDING PROTEINS MUSASHI1‐ AND MUSASHI2‐INDUCING NUCLEAR MEMBRANE ALTERATION IN ALZHEIMER'S DISEASE

Alzheimer's & dementia, 2019-07, Vol.15 (7S_Part_29)

2019

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Tau oligomers mediate aggregation of RNA‐binding proteins Musashi1 and Musashi2 inducing Lamin alteration

Aging cell, 2019-12, Vol.18 (6), p.e13035-n/a

2019

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Lysine 63-linked ubiquitination of tau oligomers contributes to the pathogenesis of Alzheimer’s disease

The Journal of biological chemistry, 2022-04, Vol.298 (4), p.101766, Article 101766

2022

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Modulating disease-relevant tau oligomeric strains by small molecules

The Journal of biological chemistry, 2020-10, Vol.295 (44), p.14807-14825

2020

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Tau modulates mRNA transcription, alternative polyadenylation (APA) profiles of hnRNPs, chromatin remodeling and spliceosome complexes

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Passive Immunotherapy Targeting Tau Oligomeric Strains Reverses Tauopathy Phenotypes in Aged Human-Tau Mice in a Mouse Model-Specific Manner

Journal of Alzheimer's disease, 2022-01, Vol.90 (3), p.1103-1122

2022

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Multiplexed Barcoding Image Analysis for Immunoprofiling and Spatial Mapping Characterization in the Single-Cell Analysis of Paraffin Tissue Samples

Journal of visualized experiments, 2023-04 (194)

2023

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EOMES+ Tr1-like Cells Are Enriched in Areas of NLPHL Group II (Patterns D to F) Supporting the Role of Tregs in Disease Recurrence/Progression

Blood, 2022-11, Vol.140 (Supplement 1), p.3593-3594

2022

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Oligomeric tau enters brain vascular endothelial cells and induces cellular senescence and brain microvascular dysfunction in tauopathy

Alzheimer's & dementia, 2023-12, Vol.19 (S13), p.n/a

2023

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P4‐520: TAU OLIGOMERS MEDIATE AGGREGATION OF RNA‐BINDING PROTEINS MUSASHI1‐ AND MUSASHI2‐INDUCING NUCLEAR MEMBRANE ALTERATION IN ALZHEIMER'S DISEASE

Alzheimer's & dementia, 2019-07, Vol.15, p.P1513-P1513

2019

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Increased expression of CD70 in relapsed acute myeloid leukemia after hypomethylating agents

Virchows Archiv : an international journal of pathology, 2024-02

2024

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P1‐021: TOXICITY AND PROPAGATION OF TBI BRAIN‐DERIVED SOLUBLE TAU STRAINS

Alzheimer's & dementia, 2018-07, Vol.14 (7S_Part_4), p.P273-P273

2018

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TOXICITY AND PROPAGATION OF TBI BRAIN-DERIVED SOLUBLE TAU STRAINS

Alzheimer's & dementia, 2018-07, Vol.14 (7), p.P273-P273

2018

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TAU AND P53 IN ALZHEIMER’S DISEASE

Alzheimer's & dementia, 2017-07, Vol.13 (7), p.P1505-P1505

2017

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EVALUATING TAU OLIGOMERS PASSIVE IMMUNOTHERAPY USING AGED TRANSGENIC ANIMALS OF TAUOPATHY

Alzheimer's & dementia, 2018-07, Vol.14 (7), p.P1657-P1657

2018

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O5‐05‐06: EVALUATING TAU OLIGOMERS PASSIVE IMMUNOTHERAPY USING AGED TRANSGENIC ANIMALS OF TAUOPATHY

Alzheimer's & dementia, 2018-07, Vol.14 (7S_Part_31), p.P1657-P1657

2018

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P-399 Isatuximab promotes immune activation in the bone marrow microenvironment of patients with high risk smoldering multiple myeloma

Clinical lymphoma, myeloma and leukemia, 2023-09, Vol.23, p.S260-S261

2023

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RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction

Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy

Internalization mechanisms of brain-derived tau oligomers from patients with Alzheimer's disease, progressive supranuclear palsy and dementia with Lewy bodies

TDP-43 and Tau Oligomers in Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia

Tau Modulates mRNA Transcription, Alternative Polyadenylation Profiles of hnRNPs, Chromatin Remodeling and Spliceosome Complexes

Formation of Toxic Oligomeric Assemblies of RNA-binding Protein: Musashi in Alzheimer's disease

Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer’s disease and frontotemporal dementia

TAU OLIGOMERS MEDIATE AGGREGATION OF RNA-BINDING PROTEINS MUSASHI1- AND MUSASHI2-INDUCING NUCLEAR MEMBRANE ALTERATION IN ALZHEIMER’S DISEASE

P4‐520: TAU OLIGOMERS MEDIATE AGGREGATION OF RNA‐BINDING PROTEINS MUSASHI1‐ AND MUSASHI2‐INDUCING NUCLEAR MEMBRANE ALTERATION IN ALZHEIMER'S DISEASE

Tau oligomers mediate aggregation of RNA‐binding proteins Musashi1 and Musashi2 inducing Lamin alteration

Lysine 63-linked ubiquitination of tau oligomers contributes to the pathogenesis of Alzheimer’s disease

Modulating disease-relevant tau oligomeric strains by small molecules

Tau modulates mRNA transcription, alternative polyadenylation (APA) profiles of hnRNPs, chromatin remodeling and spliceosome complexes

Passive Immunotherapy Targeting Tau Oligomeric Strains Reverses Tauopathy Phenotypes in Aged Human-Tau Mice in a Mouse Model-Specific Manner

Multiplexed Barcoding Image Analysis for Immunoprofiling and Spatial Mapping Characterization in the Single-Cell Analysis of Paraffin Tissue Samples

EOMES+ Tr1-like Cells Are Enriched in Areas of NLPHL Group II (Patterns D to F) Supporting the Role of Tregs in Disease Recurrence/Progression

Oligomeric tau enters brain vascular endothelial cells and induces cellular senescence and brain microvascular dysfunction in tauopathy

P4‐520: TAU OLIGOMERS MEDIATE AGGREGATION OF RNA‐BINDING PROTEINS MUSASHI1‐ AND MUSASHI2‐INDUCING NUCLEAR MEMBRANE ALTERATION IN ALZHEIMER'S DISEASE

Increased expression of CD70 in relapsed acute myeloid leukemia after hypomethylating agents

P1‐021: TOXICITY AND PROPAGATION OF TBI BRAIN‐DERIVED SOLUBLE TAU STRAINS

TOXICITY AND PROPAGATION OF TBI BRAIN-DERIVED SOLUBLE TAU STRAINS

TAU AND P53 IN ALZHEIMER’S DISEASE

EVALUATING TAU OLIGOMERS PASSIVE IMMUNOTHERAPY USING AGED TRANSGENIC ANIMALS OF TAUOPATHY

O5‐05‐06: EVALUATING TAU OLIGOMERS PASSIVE IMMUNOTHERAPY USING AGED TRANSGENIC ANIMALS OF TAUOPATHY

P-399 Isatuximab promotes immune activation in the bone marrow microenvironment of patients with high risk smoldering multiple myeloma

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