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SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair

Oncogene, 2015-11, Vol.34 (46), p.5699-5708

2015

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High speed of fork progression induces DNA replication stress and genomic instability

Nature (London), 2018-07, Vol.559 (7713), p.279-284

2018

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Immortalised breast epithelia survive prolonged DNA replication stress and return to cycle from a senescent-like state

Cell death & disease, 2014-07, Vol.5 (7), p.e1351-e1351

2014

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p53 at the crossroad of DNA replication and ribosome biogenesis stress pathways

Cell death and differentiation, 2022-05, Vol.29 (5), p.972-982

2022

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Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1

Cell death & disease, 2011-05, Vol.2 (5), p.e160-e160

2011

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The nexus of nuclear envelope dynamics, circular economy and cancer cell pathophysiology

European journal of cell biology, 2024-06, Vol.103 (2), p.151394, Article 151394

2024

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Autophagy role(s) in response to oncogenes and DNA replication stress

Cell death and differentiation, 2020-03, Vol.27 (3), p.1134-1153

2020

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Regulation of replication fork speed: Mechanisms and impact on genomic stability

DNA repair, 2019-09, Vol.81, p.102654-102654, Article 102654

2019

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BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity

Nature communications, 2016-11, Vol.7 (1), p.13398-13398, Article 13398

2016

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Differential Activity of ATR and WEE1 Inhibitors in a Highly Sensitive Subpopulation of DLBCL Linked to Replication Stress

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (14), p.3762-3775

2019

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MCM8- and MCM9-Deficient Mice Reveal Gametogenesis Defects and Genome Instability Due to Impaired Homologous Recombination

Molecular cell, 2012-08, Vol.47 (4), p.523-534

2012

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SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability

Nucleic acids research, 2018-10, Vol.46 (18), p.9484

2018

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Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1α and the NAMPT-NAD+ pathway

Nucleic acids research, 2022-09, Vol.50 (17), p.9948

2022

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The human nucleoporin Tpr protects cells from RNA-mediated replication stress

Nature communications, 2021-06, Vol.12 (1), p.3937-3937, Article 3937

2021

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TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity

The Journal of cell biology, 2016-02, Vol.212 (3), p.281-288

2016

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Human cytomegalovirus hijacks host stress response fueling replication stress and genome instability

Cell death and differentiation, 2022-08, Vol.29 (8), p.1639-1653

2022

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Gene positional changes relative to the nuclear substructure correlate with the proliferating status of hepatocytes during liver regeneration

Nucleic acids research, 2003-11, Vol.31 (21), p.6168

2003

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NAD + regulates nucleotide metabolism and genomic DNA replication

Nature cell biology, 2023, Vol.25 (12), p.1774

2023

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Super-sonic speed of DNA synthesis in medulloblastoma

Nature cancer, 2020-08, Vol.1 (8), p.758

2020

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MDC1 maintains active elongation complexes of RNA polymerase II

Cell reports (Cambridge), 2023-01, Vol.42 (1), p.111979-111979, Article 111979

2023

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Cancer cell stemness, responses to experimental genotoxic treatments, cytomegalovirus protein expression and DNA replication stress in pediatric medulloblastomas

Cell cycle (Georgetown, Tex.), 2020-04, Vol.19 (7), p.727-741

2020

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Cellular microenvironment controls the nuclear architecture of breast epithelia through β1-integrin

Cell cycle (Georgetown, Tex.), 2016, Vol.15 (3), p.345-356

2016

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Chk1 Requirement for High Global Rates of Replication Fork Progression during Normal Vertebrate S Phase

Molecular and Cellular Biology, 2006-04, Vol.26 (8), p.3319-3326

2006

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SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair

High speed of fork progression induces DNA replication stress and genomic instability

Immortalised breast epithelia survive prolonged DNA replication stress and return to cycle from a senescent-like state

p53 at the crossroad of DNA replication and ribosome biogenesis stress pathways

Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1

The nexus of nuclear envelope dynamics, circular economy and cancer cell pathophysiology

Autophagy role(s) in response to oncogenes and DNA replication stress

Regulation of replication fork speed: Mechanisms and impact on genomic stability

BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity

Differential Activity of ATR and WEE1 Inhibitors in a Highly Sensitive Subpopulation of DLBCL Linked to Replication Stress

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

MCM8- and MCM9-Deficient Mice Reveal Gametogenesis Defects and Genome Instability Due to Impaired Homologous Recombination

SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability

Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1α and the NAMPT-NAD+ pathway

A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization

The human nucleoporin Tpr protects cells from RNA-mediated replication stress

TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity

Human cytomegalovirus hijacks host stress response fueling replication stress and genome instability

Gene positional changes relative to the nuclear substructure correlate with the proliferating status of hepatocytes during liver regeneration

NAD + regulates nucleotide metabolism and genomic DNA replication

Super-sonic speed of DNA synthesis in medulloblastoma

MDC1 maintains active elongation complexes of RNA polymerase II

Cancer cell stemness, responses to experimental genotoxic treatments, cytomegalovirus protein expression and DNA replication stress in pediatric medulloblastomas

Cellular microenvironment controls the nuclear architecture of breast epithelia through β1-integrin

Chk1 Requirement for High Global Rates of Replication Fork Progression during Normal Vertebrate S Phase

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