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The interleukin (IL)-1 cytokine family – Balance between agonists and antagonists in inflammatory diseases

Cytokine (Philadelphia, Pa.), 2015-11, Vol.76 (1), p.25-37

2015

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Unopposed IL-18 signaling leads to severe TLR9-induced macrophage activation syndrome in mice

Blood, 2018-03, Vol.131 (13), p.1430-1441

2018

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IL-1 Family Antagonists in Mouse and Human Skin Inflammation

Frontiers in immunology, 2021-03, Vol.12, p.652846-652846

2021

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Interleukin-36 potently stimulates human M2 macrophages, Langerhans cells and keratinocytes to produce pro-inflammatory cytokines

Cytokine (Philadelphia, Pa.), 2016-08, Vol.84, p.88-98

2016

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Deficiency in IL-1 Receptor Type 2 Aggravates K/BxN Serum Transfer-Induced Arthritis in Mice but Has No Impact on Systemic Inflammatory Responses

The Journal of immunology (1950), 2017-04, Vol.198 (7), p.2916-2926

2017

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β Cell-Specific Deletion of the IL-1 Receptor Antagonist Impairs β Cell Proliferation and Insulin Secretion

Cell reports (Cambridge), 2018-02, Vol.22 (7), p.1774-1786

2018

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Granzyme A Contributes to Inflammatory Arthritis in Mice Through Stimulation of Osteoclastogenesis

Arthritis & rheumatology (Hoboken, N.J.), 2017-02, Vol.69 (2), p.320-334

2017

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Mouse neutrophils express the decoy type 2 interleukin-1 receptor (IL-1R2) constitutively and in acute inflammatory conditions

Journal of leukocyte biology, 2013-10, Vol.94 (4), p.791-802

2013

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The severity of experimental arthritis is independent of IL-36 receptor signaling

Arthritis research & therapy, 2013-03, Vol.15 (2), p.R38-R38

2013

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The biology of cytotoxic cell granule exocytosis pathway: granzymes have evolved to induce cell death and inflammation

Microbes and infection, 2009-04, Vol.11 (4), p.452-459

2009

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Atherosclerosis severity is not affected by a deficiency in IL‐33/ST2 signaling

Immunity, Inflammation and Disease, 2015-09, Vol.3 (3), p.239-246

2015

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Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α

The Journal of immunology (1950), 2020-02, Vol.204 (4), p.967-979

2020

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IL-36R ligands are potent regulators of dendritic and T cells

Blood, 2011-11, Vol.118 (22), p.5813-5823

2011

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IL-36 signaling amplifies Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells

Blood, 2012-10, Vol.120 (17), p.3478-3487

2012

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Severe neutrophil-dominated inflammation and enhanced myelopoiesis in IL-33-overexpressing CMV/IL33 mice

The Journal of immunology (1950), 2015-01, Vol.194 (2), p.750-760

2015

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Perforin and Fas Act Together in the Induction of Apoptosis, and Both Are Critical in the Clearance of Lymphocytic Choriomeningitis Virus Infection

Journal of Virology, 2004-11, Vol.78 (22), p.12395-12405

2004

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Mouse granzyme K has pro-inflammatory potential

Cell death and differentiation, 2011-07, Vol.18 (7), p.1112-1119

2011

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Secretory lysosomes of mouse mast cells store and exocytose active caspase‐3 in a strictly granzyme B dependent manner

European journal of immunology, 2013-12, Vol.43 (12), p.3209-3218

2013

Volltextzugriff (PDF)

ID: 138: Deficiency in IL-1 receptor type 2 aggravates K/BxN serum transfer-induced arthritis in mice, but has no effect in endotoxemia

Cytokine (Philadelphia, Pa.), 2015-11, Vol.76 (1), p.92-92

2015

Volltextzugriff (PDF)

ID: 138

Cytokine (Philadelphia, Pa.), 2015-11, Vol.76 (1), p.92

2015

Volltextzugriff (PDF)

Disease severity in K/BxN serum transfer-induced arthritis is not affected by IL-33 deficiency

Arthritis research & therapy, 2013-01, Vol.15 (1), p.R13-R13

2013

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Immune-mediated experimental arthritis in IL-33 deficient mice

Cytokine (Philadelphia, Pa.), 2014-09, Vol.69 (1), p.68-74

2014

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ID: 133

Cytokine (Philadelphia, Pa.), 2015-11, Vol.76 (1), p.91

2015

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ID: 133: IL-36 acts on myeloid cells and exerts stronger stimulatory effects compared to IL-1 in M2-polarized macrophages

Cytokine (Philadelphia, Pa.), 2015-11, Vol.76 (1), p.91-91

2015

Volltextzugriff (PDF)

Articular inflammation is controlled by myeloid cell-derived interleukin 1 receptor antagonist during the acute phase of arthritis in mice

Annals of the rheumatic diseases, 2012-02, Vol.71 (2), p.281-287

2012

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The interleukin (IL)-1 cytokine family – Balance between agonists and antagonists in inflammatory diseases

Unopposed IL-18 signaling leads to severe TLR9-induced macrophage activation syndrome in mice

IL-1 Family Antagonists in Mouse and Human Skin Inflammation

Interleukin-36 potently stimulates human M2 macrophages, Langerhans cells and keratinocytes to produce pro-inflammatory cytokines

Deficiency in IL-1 Receptor Type 2 Aggravates K/BxN Serum Transfer-Induced Arthritis in Mice but Has No Impact on Systemic Inflammatory Responses

β Cell-Specific Deletion of the IL-1 Receptor Antagonist Impairs β Cell Proliferation and Insulin Secretion

Granzyme A Contributes to Inflammatory Arthritis in Mice Through Stimulation of Osteoclastogenesis

Mouse neutrophils express the decoy type 2 interleukin-1 receptor (IL-1R2) constitutively and in acute inflammatory conditions

The severity of experimental arthritis is independent of IL-36 receptor signaling

The biology of cytotoxic cell granule exocytosis pathway: granzymes have evolved to induce cell death and inflammation

Atherosclerosis severity is not affected by a deficiency in IL‐33/ST2 signaling

Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α

IL-36R ligands are potent regulators of dendritic and T cells

IL-36 signaling amplifies Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells

Severe neutrophil-dominated inflammation and enhanced myelopoiesis in IL-33-overexpressing CMV/IL33 mice

Perforin and Fas Act Together in the Induction of Apoptosis, and Both Are Critical in the Clearance of Lymphocytic Choriomeningitis Virus Infection

Mouse granzyme K has pro-inflammatory potential

Secretory lysosomes of mouse mast cells store and exocytose active caspase‐3 in a strictly granzyme B dependent manner

ID: 138: Deficiency in IL-1 receptor type 2 aggravates K/BxN serum transfer-induced arthritis in mice, but has no effect in endotoxemia

ID: 138

Disease severity in K/BxN serum transfer-induced arthritis is not affected by IL-33 deficiency

Immune-mediated experimental arthritis in IL-33 deficient mice

ID: 133

ID: 133: IL-36 acts on myeloid cells and exerts stronger stimulatory effects compared to IL-1 in M2-polarized macrophages

Articular inflammation is controlled by myeloid cell-derived interleukin 1 receptor antagonist during the acute phase of arthritis in mice

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