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Mechanisms of Gβγ Release upon GPCR Activation

Trends in biochemical sciences (Amsterdam. Regular ed.), 2021-09, Vol.46 (9), p.703-704

Martemyanov, Kirill A.

2021

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Exploring pharmacological inhibition of Gq/11 as an analgesic strategy

British journal of pharmacology, 2022-12, Vol.179 (23), p.5196-5208

2022

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Pharmacogenomics of GPCR Drug Targets

Cell, 2018-01, Vol.172 (1-2), p.41-54.e19

2018

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Distinct profiles of functional discrimination among G proteins determine the actions of G protein-coupled receptors

Science signaling, 2015-12, Vol.8 (405), p.ra123

2015

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Exploring pharmacological inhibition of G q/11 as an analgesic strategy

British journal of pharmacology, 2022-12, Vol.179 (23), p.5196-5208

2022

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Beyond the Ligand: Extracellular and Transcellular G Protein-Coupled Receptor Complexes in Physiology and Pharmacology

Pharmacological reviews, 2019-10, Vol.71 (4), p.503-519

2019

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The role of orphan receptor GPR139 in neuropsychiatric behavior

Neuropsychopharmacology (New York, N.Y.), 2022-03, Vol.47 (4), p.902-913

2022

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Publisher Correction: Cryo-EM structure of human class C orphan GPCR GPR179 involved in visual processing

Nature communications, 2024-10, Vol.15 (1), p.9083-1, Article 9083

2024

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Cryo-EM structure of human class C orphan GPCR GPR179 involved in visual processing

Nature communications, 2024-09, Vol.15 (1), p.8299-13, Article 8299

2024

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Community guidelines for GPCR ligand bias: IUPHAR review 32

British journal of pharmacology, 2022-07, Vol.179 (14), p.3651-3674

2022

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Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors

Cell reports (Cambridge), 2018-10, Vol.25 (1), p.130-145.e5

2018

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A Global Map of G Protein Signaling Regulation by RGS Proteins

Cell, 2020-10, Vol.183 (2), p.503-521.e19

2020

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The signaling proteins GPR158 and RGS7 modulate excitability of L2/3 pyramidal neurons and control A-type potassium channel in the prelimbic cortex

The Journal of biological chemistry, 2019-08, Vol.294 (35), p.13145-13157

2019

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TRPM1 forms complexes with nyctalopin in vivo and accumulates in postsynaptic compartment of ON-bipolar neurons in mGluR6-dependent manner

The Journal of neuroscience, 2011-08, Vol.31 (32), p.11521-11526

2011

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NF1-cAMP signaling dissociates cell type-specific contributions of striatal medium spiny neurons to reward valuation and motor control

PLoS biology, 2019-10, Vol.17 (10), p.e3000477-e3000477

2019

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Mechanism for Selective Synaptic Wiring of Rod Photoreceptors into the Retinal Circuitry and Its Role in Vision

Neuron (Cambridge, Mass.), 2015-09, Vol.87 (6), p.1248-1260

2015

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The orphan receptor GPR139 signals via Gq/11 to oppose opioid effects

The Journal of biological chemistry, 2020-07, Vol.295 (31), p.10822-10830

2020

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Genetic modeling of GNAO1 disorder delineates mechanisms of Gαo dysfunction

Human molecular genetics, 2022-02, Vol.31 (4), p.510-522

2022

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Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor

Nature communications, 2018-05, Vol.9 (1), p.1996-15, Article 1996

2018

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ELFN2 is a postsynaptic cell adhesion molecule with essential roles in controlling group III mGluRs in the brain and neuropsychiatric behavior

Molecular psychiatry, 2019-12, Vol.24 (12), p.1902-1919

2019

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Caspase-2 promotes AMPA receptor internalization and cognitive flexibility via mTORC2-AKT-GSK3β signaling

Nature communications, 2019-08, Vol.10 (1), p.3622-13, Article 3622

2019

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Orphan receptor GPR179 forms macromolecular complexes with components of metabotropic signaling cascade in retina ON-bipolar neurons

Investigative ophthalmology & visual science, 2013-10, Vol.54 (10), p.7153-7161

2013

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Orphan receptor GPR158 serves as a metabotropic glycine receptor: mGlyR

Science (American Association for the Advancement of Science), 2023-03, Vol.379 (6639), p.1352-1358

2023

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An Input-Specific Orphan Receptor GPR158-HSPG Interaction Organizes Hippocampal Mossy Fiber-CA3 Synapses

Neuron (Cambridge, Mass.), 2018-10, Vol.100 (1), p.201-215.e9

2018

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Monitoring G Protein Activation in Cells with BRET

Methods in molecular biology (Clifton, N.J.), 2015, Vol.1335, p.107

2015

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Mechanisms of Gβγ Release upon GPCR Activation

Exploring pharmacological inhibition of Gq/11 as an analgesic strategy

Pharmacogenomics of GPCR Drug Targets

Distinct profiles of functional discrimination among G proteins determine the actions of G protein-coupled receptors

Exploring pharmacological inhibition of G q/11 as an analgesic strategy

Beyond the Ligand: Extracellular and Transcellular G Protein-Coupled Receptor Complexes in Physiology and Pharmacology

The role of orphan receptor GPR139 in neuropsychiatric behavior

Publisher Correction: Cryo-EM structure of human class C orphan GPCR GPR179 involved in visual processing

Cryo-EM structure of human class C orphan GPCR GPR179 involved in visual processing

Community guidelines for GPCR ligand bias: IUPHAR review 32

Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors

A Global Map of G Protein Signaling Regulation by RGS Proteins

The signaling proteins GPR158 and RGS7 modulate excitability of L2/3 pyramidal neurons and control A-type potassium channel in the prelimbic cortex

TRPM1 forms complexes with nyctalopin in vivo and accumulates in postsynaptic compartment of ON-bipolar neurons in mGluR6-dependent manner

NF1-cAMP signaling dissociates cell type-specific contributions of striatal medium spiny neurons to reward valuation and motor control

Mechanism for Selective Synaptic Wiring of Rod Photoreceptors into the Retinal Circuitry and Its Role in Vision

The orphan receptor GPR139 signals via Gq/11 to oppose opioid effects

Genetic modeling of GNAO1 disorder delineates mechanisms of Gαo dysfunction

Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor

ELFN2 is a postsynaptic cell adhesion molecule with essential roles in controlling group III mGluRs in the brain and neuropsychiatric behavior

Caspase-2 promotes AMPA receptor internalization and cognitive flexibility via mTORC2-AKT-GSK3β signaling

Orphan receptor GPR179 forms macromolecular complexes with components of metabotropic signaling cascade in retina ON-bipolar neurons

Orphan receptor GPR158 serves as a metabotropic glycine receptor: mGlyR

An Input-Specific Orphan Receptor GPR158-HSPG Interaction Organizes Hippocampal Mossy Fiber-CA3 Synapses

Monitoring G Protein Activation in Cells with BRET

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