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6-Aryl-2,4-dioxo-5-hexenoic acids, novel integrase inhibitors active against HIV-1 multiplication in cell-based assays

Bioorganic & medicinal chemistry letters, 2004-04, Vol.14 (7), p.1745-1749

2004

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Geometrically and Conformationally Restrained Cinnamoyl Compounds as Inhibitors of HIV-1 Integrase: Synthesis, Biological Evaluation, and Molecular Modeling

Journal of medicinal chemistry, 1998-10, Vol.41 (21), p.3948-3960

1998

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1,2,5-Benzothiadiazepine and Pyrrolo[2,1-d]-[1,2,5]Benzothiadiazepine Derivatives with Specific Anti-Human Immunodeficiency Virus Type 1 Activity

Antiviral chemistry & chemotherapy, 1998-03, Vol.9 (2), p.127-137

1998

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5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3,4-dihydropyrimidin-4(3H)-ones: Novel Potent and Selective Dihydro-alkoxy-benzyl-oxopyrimidine Derivatives

Journal of medicinal chemistry, 1999-02, Vol.42 (4), p.619-627

1999

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Synthesis and Biological Evaluation of 5H-Indolo [3,2-b][1,5]Benzothiazepine Derivatives, Designed as Conformationally Constrained Analogues of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitor L-737,126

Antiviral Chemistry and Chemotherapy, 1998-03, Vol.9 (2), p.139-148

1998

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Antimicrobial and antineoplastic activities of new 4-diazopyrazole derivatives

European journal of medicinal chemistry, 1998-06, Vol.33 (5), p.375-382

1998

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Structure-Based Design, Parallel Synthesis, Structure−Activity Relationship, and Molecular Modeling Studies of Thiocarbamates, New Potent Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitor Isosteres of Phenethylthiazolylthiourea Derivatives

Journal of medicinal chemistry, 2005-06, Vol.48 (11), p.3858-3873

2005

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Anti-HIV-1 integrase drugs: how far from the shelf?

Current pharmaceutical design, 2000-03, Vol.6 (5), p.569-584

2000

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Derivatives of the New Ring System Indolo[1,2-c]benzo[1,2,3]triazine with Potent Antitumor and Antimicrobial Activity

Journal of medicinal chemistry, 1999-07, Vol.42 (14), p.2561-2568

1999

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Synthesis and antimicrobial activity of new 3-(1-R-3(5)-methyl-4-nitroso-1H-5(3)-pyrazolyl)-5-methylisoxazoles

Bioorganic & medicinal chemistry, 2000-12, Vol.8 (12), p.2719-2728

2000

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Pyrazole-related nucleosides. Synthesis and antiviral/antitumor activity of some substituted pyrazole and pyrazolo[4,3-d]-1,2,3-triazin-4-one nucleosides

Journal of medicinal chemistry, 1992-03, Vol.35 (5), p.917-924

1992

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Synthesis and antiproliferative activity of basic thioanalogues of merbarone

Bioorganic & medicinal chemistry, 2003-06, Vol.11 (12), p.2575-2589

2003

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Potent and Selective Inhibitors of Human Immunodeficiency Virus Protease Structurally Related to L-694,746

Antiviral chemistry & chemotherapy, 1998-08, Vol.9 (4), p.21-27

1998

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Structure—Activity Relationship Studies on New DABOs: Effect of Substitutions at Pyrimidine C-5 and C-6 Positions on Anti-HIV-1 Activity

Antiviral chemistry & chemotherapy, 2001-01, Vol.12 (1), p.37-50

2001

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3,4-Dihydro-2-Alkoxy-6-Benzyl-4-Oxopyrimidines (DABOs): A New Class of Specific Inhibitors of Human Immunodeficiency Virus Type 1

Antiviral chemistry & chemotherapy, 1993-12, Vol.4 (6), p.361-368

1993

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2-Triazenopyrroles: synthesis and biological activity

European journal of medicinal chemistry, 1999-04, Vol.34 (4), p.353-360

1999

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Peptide T-araC conjugates: solid-phase synthesis and biological activity of N 4 -(acylpeptidyl)-araC

Bioorganic & medicinal chemistry, 2000-03, Vol.8 (3), p.539-547

2000

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Structure-Activity Relationship Studies on Potential Non-Nucleoside DABO-Like Inhibitors of HIV-1 Reverse Transcriptase

Antiviral chemistry & chemotherapy, 2000-03, Vol.11 (2), p.117-133

2000

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Synthesis, antimicrobial and antiviral activities of isotrimethoprim and some related derivatives

European journal of medicinal chemistry, 1992-04, Vol.27 (3), p.251-257

1992

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Native oligodeoxynucleotides specifically active against human immunodeficiency virus type 1 in vitro: a G-quartet-driven effect?

Antimicrobial Agents and Chemotherapy, 1996-09, Vol.40 (9), p.2034-2038

1996

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5-Alkyl-2-(alkylthio)-6- (2,6-dihalophenylmethyl)-3,4-dihydro pyrimidin-4 (3H)-ones: Novel Potent and Selective Dihydro-alkoxy-benzyl-oxopyrimidine Derivatives

Journal of medicinal chemistry, 1999-02, Vol.42 (4), p.619-627

1999

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Modulatory effect of N-acetyl-L-cysteine on the HIV-1 multiplication in chronically and acutely infected cell lines

Antiviral research, 1993-09, Vol.22 (1), p.31-43

1993

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DABOs as candidates to prevent mucosal HIV transmission

Antiviral chemistry & chemotherapy, 2001, Vol.12, p.51-59

2001

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Potent and selective inhibitors of human immunodeficiency virus protease structurally related to L-694,746

Antiviral chemistry & chemotherapy, 1998-07, Vol.9 (4), p.303-309

1998

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Synthesis and antimicrobial and cytotoxic activities of pyrrole-containing analogs of trichostatin A

Journal of medicinal chemistry, 1990-10, Vol.33 (10), p.2845-2849

1990

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6-Aryl-2,4-dioxo-5-hexenoic acids, novel integrase inhibitors active against HIV-1 multiplication in cell-based assays

Geometrically and Conformationally Restrained Cinnamoyl Compounds as Inhibitors of HIV-1 Integrase: Synthesis, Biological Evaluation, and Molecular Modeling

1,2,5-Benzothiadiazepine and Pyrrolo[2,1-d]-[1,2,5]Benzothiadiazepine Derivatives with Specific Anti-Human Immunodeficiency Virus Type 1 Activity

5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3,4-dihydropyrimidin-4(3H)-ones: Novel Potent and Selective Dihydro-alkoxy-benzyl-oxopyrimidine Derivatives

Synthesis and Biological Evaluation of 5H-Indolo [3,2-b][1,5]Benzothiazepine Derivatives, Designed as Conformationally Constrained Analogues of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitor L-737,126

Antimicrobial and antineoplastic activities of new 4-diazopyrazole derivatives

Structure-Based Design, Parallel Synthesis, Structure−Activity Relationship, and Molecular Modeling Studies of Thiocarbamates, New Potent Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitor Isosteres of Phenethylthiazolylthiourea Derivatives

Anti-HIV-1 integrase drugs: how far from the shelf?

Derivatives of the New Ring System Indolo[1,2-c]benzo[1,2,3]triazine with Potent Antitumor and Antimicrobial Activity

Synthesis and antimicrobial activity of new 3-(1-R-3(5)-methyl-4-nitroso-1H-5(3)-pyrazolyl)-5-methylisoxazoles

Pyrazole-related nucleosides. Synthesis and antiviral/antitumor activity of some substituted pyrazole and pyrazolo[4,3-d]-1,2,3-triazin-4-one nucleosides

Synthesis and antiproliferative activity of basic thioanalogues of merbarone

Potent and Selective Inhibitors of Human Immunodeficiency Virus Protease Structurally Related to L-694,746

Structure—Activity Relationship Studies on New DABOs: Effect of Substitutions at Pyrimidine C-5 and C-6 Positions on Anti-HIV-1 Activity

3,4-Dihydro-2-Alkoxy-6-Benzyl-4-Oxopyrimidines (DABOs): A New Class of Specific Inhibitors of Human Immunodeficiency Virus Type 1

2-Triazenopyrroles: synthesis and biological activity

Peptide T-araC conjugates: solid-phase synthesis and biological activity of N 4 -(acylpeptidyl)-araC

Structure-Activity Relationship Studies on Potential Non-Nucleoside DABO-Like Inhibitors of HIV-1 Reverse Transcriptase

Synthesis, antimicrobial and antiviral activities of isotrimethoprim and some related derivatives

Native oligodeoxynucleotides specifically active against human immunodeficiency virus type 1 in vitro: a G-quartet-driven effect?

5-Alkyl-2-(alkylthio)-6- (2,6-dihalophenylmethyl)-3,4-dihydro pyrimidin-4 (3H)-ones: Novel Potent and Selective Dihydro-alkoxy-benzyl-oxopyrimidine Derivatives

Modulatory effect of N-acetyl-L-cysteine on the HIV-1 multiplication in chronically and acutely infected cell lines

DABOs as candidates to prevent mucosal HIV transmission

Potent and selective inhibitors of human immunodeficiency virus protease structurally related to L-694,746

Synthesis and antimicrobial and cytotoxic activities of pyrrole-containing analogs of trichostatin A

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