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Synthesis and Biological Evaluation of Novel 2-Aroyl Benzofuran-Based Hydroxamic Acids as Antimicrotubule Agents

International journal of molecular sciences, 2024-07, Vol.25 (14), p.7519

2024

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Autophagic flux inhibition enhances cytotoxicity of the receptor tyrosine kinase inhibitor ponatinib

Journal of experimental & clinical cancer research, 2020-09, Vol.39 (1), p.1-195, Article 195

2020

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Molecular and functional profiling of chemotolerant cells unveils nucleoside metabolism-dependent vulnerabilities in medulloblastoma

Acta neuropathologica communications, 2023-11, Vol.11 (1), p.1-183, Article 183

2023

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Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities

Pharmaceuticals (Basel, Switzerland), 2022-08, Vol.15 (8), p.1031

2022

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Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents

Pharmaceutics, 2022-06, Vol.14 (6), p.1191

2022

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Biological Evaluation of New Thienopyridinium and Thienopyrimidinium Derivatives as Human Choline Kinase Inhibitors

Pharmaceutics, 2022-03, Vol.14 (4), p.715

2022

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Anticancer and Structure Activity Relationship of Non-Symmetrical Choline Kinase Inhibitors

Pharmaceutics, 2021-08, Vol.13 (9), p.1360

2021

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A BAG's life: Every connection matters in cancer

Pharmacology & therapeutics (Oxford), 2020-05, Vol.209, p.107498, Article 107498

2020

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Design, synthesis and biological evaluation of novel 2,4-thiazolidinedione derivatives able to target the human BAG3 protein

European journal of medicinal chemistry, 2023-12, Vol.261, p.115824, Article 115824

2023

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MODL-20. Metabolic rewiring support the onset of chemotherapy resistance in medulloblastoma

Neuro-oncology (Charlottesville, Va.), 2022-06, Vol.24 (Supplement_1), p.i173-i173

2022

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BAG1 down‐regulation increases chemo‐sensitivity of acute lymphoblastic leukaemia cells

Journal of cellular and molecular medicine, 2021-09, Vol.25 (18), p.9060-9065

2021

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Cinnamic acid derivatives linked to arylpiperazines as novel potent inhibitors of tyrosinase activity and melanin synthesis

European journal of medicinal chemistry, 2022-03, Vol.231, p.114147-114147, Article 114147

2022

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Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors

European journal of medicinal chemistry, 2020-08, Vol.200, p.112448, Article 112448

2020

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Identification of Homoharringtonine as a potent inhibitor of glioblastoma cell proliferation and migration

Translational research : the journal of laboratory and clinical medicine, 2023-01, Vol.251, p.41-53

2023

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MODL-21. Multi-omics investigation of medulloblastoma resistant models reveals functional association between intracellular regulatory networks and drug susceptibility

Neuro-oncology (Charlottesville, Va.), 2022-06, Vol.24 (Supplement_1), p.i173-i173

2022

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TP-0903 inhibits neuroblastoma cell growth and enhances the sensitivity to conventional chemotherapy

European journal of pharmacology, 2018-01, Vol.818, p.435-448

2018

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SYK Targeting Represents a Potential Therapeutic Option for Relapsed Resistant Pediatric ETV6-RUNX1 B-Acute Lymphoblastic Leukemia Patients

International journal of molecular sciences, 2019-12, Vol.20 (24), p.6175

2019

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Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors

European journal of medicinal chemistry, 2019-11, Vol.181, p.111577-111577, Article 111577

2019

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The Transcription Factors NFATc1 and NFATc2 Control Glucocorticoid Resistance in Pediatric T-Cell Acute Lymphoblastic Leukemia

Blood, 2023-11, Vol.142 (Supplement 1), p.420-420

2023

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AKR1C enzymes sustain therapy resistance in paediatric T-ALL

British journal of cancer, 2018-04, Vol.118 (7), p.985-994

2018

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Abstract A058: Dielectric characterization of glioblastoma cancer stem cells

Molecular cancer therapeutics, 2019-12, Vol.18 (12_Supplement), p.A058-A058

2019

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Histone Deacetylase Inhibitors Impair Glioblastoma Cell Motility and Proliferation

Cancers, 2022-04, Vol.14 (8), p.1897

2022

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Design, Synthesis, and Biological Evaluation of 6‑Substituted Thieno[3,2‑d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors

Journal of medicinal chemistry, 2019-02, Vol.62 (3), p.1274-1290

2019

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Developing novel classes of protein kinase CK1δ inhibitors by fusing [1,2,4]triazole with different bicyclic heteroaromatic systems

European journal of medicinal chemistry, 2021-04, Vol.216, p.113331, Article 113331

2021

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Abstract A066: Role of the NRF2 signaling pathway in sustaining chemoresistance in medulloblastoma

Molecular cancer therapeutics, 2019-12, Vol.18 (12_Supplement), p.A066-A066

2019

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Synthesis and Biological Evaluation of Novel 2-Aroyl Benzofuran-Based Hydroxamic Acids as Antimicrotubule Agents

Autophagic flux inhibition enhances cytotoxicity of the receptor tyrosine kinase inhibitor ponatinib

Molecular and functional profiling of chemotolerant cells unveils nucleoside metabolism-dependent vulnerabilities in medulloblastoma

Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities

Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents

Biological Evaluation of New Thienopyridinium and Thienopyrimidinium Derivatives as Human Choline Kinase Inhibitors

Anticancer and Structure Activity Relationship of Non-Symmetrical Choline Kinase Inhibitors

A BAG's life: Every connection matters in cancer

Design, synthesis and biological evaluation of novel 2,4-thiazolidinedione derivatives able to target the human BAG3 protein

MODL-20. Metabolic rewiring support the onset of chemotherapy resistance in medulloblastoma

BAG1 down‐regulation increases chemo‐sensitivity of acute lymphoblastic leukaemia cells

Cinnamic acid derivatives linked to arylpiperazines as novel potent inhibitors of tyrosinase activity and melanin synthesis

Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors

Identification of Homoharringtonine as a potent inhibitor of glioblastoma cell proliferation and migration

MODL-21. Multi-omics investigation of medulloblastoma resistant models reveals functional association between intracellular regulatory networks and drug susceptibility

TP-0903 inhibits neuroblastoma cell growth and enhances the sensitivity to conventional chemotherapy

SYK Targeting Represents a Potential Therapeutic Option for Relapsed Resistant Pediatric ETV6-RUNX1 B-Acute Lymphoblastic Leukemia Patients

Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors

The Transcription Factors NFATc1 and NFATc2 Control Glucocorticoid Resistance in Pediatric T-Cell Acute Lymphoblastic Leukemia

AKR1C enzymes sustain therapy resistance in paediatric T-ALL

Abstract A058: Dielectric characterization of glioblastoma cancer stem cells

Histone Deacetylase Inhibitors Impair Glioblastoma Cell Motility and Proliferation

Design, Synthesis, and Biological Evaluation of 6‑Substituted Thieno[3,2‑d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors

Developing novel classes of protein kinase CK1δ inhibitors by fusing [1,2,4]triazole with different bicyclic heteroaromatic systems

Abstract A066: Role of the NRF2 signaling pathway in sustaining chemoresistance in medulloblastoma

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