UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions

Microvascular research, 2009-03, Vol.77 (2), p.78-86

2009

Volltextzugriff (PDF)

A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos

Journal of medicinal chemistry, 2018-01, Vol.61 (2), p.535-542

2018

Volltextzugriff (PDF)

Isosteric analogs of lenalidomide and pomalidomide: Synthesis and biological activity

Bioorganic & medicinal chemistry letters, 2013-01, Vol.23 (1), p.360-365

2013

Volltextzugriff (PDF)

1,1-Diarylalkenes as anticancer agents: Dual inhibitors of tubulin polymerization and phosphodiesterase 4

Bioorganic & medicinal chemistry, 2011-11, Vol.19 (21), p.6356-6374

2011

Volltextzugriff (PDF)

Enhancement of cytokine production and AP-1 transcriptional activity in T cells by thalidomide-related immunomodulatory drugs

The Journal of pharmacology and experimental therapeutics, 2003-06, Vol.305 (3), p.1222-1232

2003

Volltextzugriff (PDF)

Discovery of (S)-N-{2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide (Apremilast), a Potent and Orally Active Phosphodiesterase 4 and Tumor Necrosis Factor-a Inhibitor

Journal of medicinal chemistry, 2009-03, Vol.52 (6), p.1522-1524

2009

Volltextzugriff (PDF)

Asymmetric Synthesis of Stegobinone via Boronic Ester Chemistry

Journal of the American Chemical Society, 1996-05, Vol.118 (19), p.4560-4566

1996

Volltextzugriff (PDF)

A Highly Enantioselective and Diastereoselective Synthesis of Cyclobutanes via Boronic Esters

Organic letters, 1999-08, Vol.1 (3), p.379-382

1999

Volltextzugriff (PDF)

Antiproliferative effects of CC-8062 and CC-8075 in pancreatic cancer cells

Pancreas, 2009-01, Vol.38 (1), p.78-84

2009

Volltextzugriff (PDF)

Nonpeptide Cyclic Cyanoguanidines as HIV-1 Protease Inhibitors: Synthesis, Structure−Activity Relationships, and X-ray Crystal Structure Studies

Journal of medicinal chemistry, 1998-04, Vol.41 (9), p.1446-1455

1998

Volltextzugriff (PDF)

α-Fluoro-substituted thalidomide analogues

Bioorganic & medicinal chemistry letters, 2003-10, Vol.13 (20), p.3415-3417

2003

Volltextzugriff (PDF)

Enantioselective Capture and Retroracemization of (1-Bromoalkyl)boronic Esters by an N-Propanoyloxazolidinone Enolate and Iodide Ion

Journal of organic chemistry, 1994-09, Vol.59 (19), p.5734-5741

1994

Volltextzugriff (PDF)

A novel subclass of thalidomide analogue with anti-solid tumor activity in which caspase-dependent apoptosis is associated with altered expression of bcl-2 family proteins

Cancer research (Chicago, Ill.), 2003-02, Vol.63 (3), p.593-599

2003

Volltextzugriff (PDF)

Potent inhibition of cytokine production from intestinal lamina propria T cells by phosphodiesterase-4 inhibitory thalidomide analogues

Journal of clinical immunology, 2001-09, Vol.21 (5), p.357-364

2001

Volltextzugriff (PDF)

Effect of 3-fluorothalidomide and 3-methylthalidomide enantiomers on tumor necrosis factor production and antitumor responses to the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)

Oncology research, 2003, Vol.14 (2), p.75-82

2003

Volltextzugriff (PDF)

Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS

Nature (London), 2015-07, Vol.523 (7559), p.183-188

2015

Volltextzugriff (PDF)

Selective cytokine inhibitory drugs with enhanced antiangiogenic activity control tumor growth through vascular inhibition

Cancer research (Chicago, Ill.), 2003-12, Vol.63 (23), p.8073-8078

2003

Volltextzugriff (PDF)

Hydrolysis of Substituted 1,3,2-Dioxaborolanes and an Asymmetric Synthesis of a Differentially Protected syn,syn-3-Methyl-2,4-hexanediol

Journal of organic chemistry, 1996-08, Vol.61 (17), p.6047-6051

1996

Volltextzugriff (PDF)

Synthesis of 7-membered cyclic oxamides: Novel HIV-1 protease inhibitors

Tetrahedron letters, 1996-02, Vol.37 (8), p.1153-1156

1996

Volltextzugriff (PDF)

Discovery of (S)-N-{2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide (Apremilast), a Potent and Orally Active Phosphodiesterase 4 and Tumor Necrosis Factor-α Inhibitor

Journal of medicinal chemistry, 2009-03, Vol.52 (6), p.1522-1524

2009

Volltextzugriff (PDF)

Direct Synthesis of [α-[(tert-Butoxycarbonyl)amino]alkyl]- boronates from (α-Haloalkyl)boronates

Journal of organic chemistry, 1996-11, Vol.61 (22), p.7951-7954

1996

Volltextzugriff (PDF)

High-precision asymmetric synthesis of stegobiol and stegobinone via boronic esters

Journal of organic chemistry, 1993-11, Vol.58 (24), p.6545-6547

1993

Volltextzugriff (PDF)

Protein Degradation via CRL4 CRBN Ubiquitin Ligase: Discovery and Structure-Activity Relationships of Novel Glutarimide Analogs That Promote Degradation of Aiolos and/or GSPT1

Journal of medicinal chemistry, 2018-01, Vol.61 (2), p.492-503

2018

Volltextzugriff (PDF)

Protein Degradation via CRL4CRBN Ubiquitin Ligase: Discovery and Structure–Activity Relationships of Novel Glutarimide Analogs That Promote Degradation of Aiolos and/or GSPT1

Journal of medicinal chemistry, 2018-01, Vol.61 (2), p.492-503

2018

Volltextzugriff (PDF)

1 – 25 von 87

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(76)
Mit Volltextzugriff
(78)

Publikationsform

Sprache

Englisch
(87)
Japanisch
(2)

Erscheinungsjahr

n.n

Thema

Science & Technology
(59)
Life Sciences & Biomedicine
(40)
Humans
(38)
Chemistry
(24)
Physical Sciences
(24)
Female
(18)
Male
(16)
Animals
(14)
Biological And Medical Sciences
(14)
Middle Aged
(14)
Aged
(13)
Chemistry, Organic
(12)
Medical Sciences
(12)
Mice
(10)
Thalidomide - Analogs & Derivatives
(10)
Cardiovascular System & Cardiology
(9)
Pharmacology & Pharmacy
(9)
Pharmacology. Drug Treatments
(9)
Cardiac & Cardiovascular Systems
(8)
Thalidomide - Pharmacology
(8)

15 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL

The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions

A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos

Isosteric analogs of lenalidomide and pomalidomide: Synthesis and biological activity

1,1-Diarylalkenes as anticancer agents: Dual inhibitors of tubulin polymerization and phosphodiesterase 4

Enhancement of cytokine production and AP-1 transcriptional activity in T cells by thalidomide-related immunomodulatory drugs

Discovery of (S)-N-{2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide (Apremilast), a Potent and Orally Active Phosphodiesterase 4 and Tumor Necrosis Factor-a Inhibitor

Asymmetric Synthesis of Stegobinone via Boronic Ester Chemistry

A Highly Enantioselective and Diastereoselective Synthesis of Cyclobutanes via Boronic Esters

Antiproliferative effects of CC-8062 and CC-8075 in pancreatic cancer cells

Nonpeptide Cyclic Cyanoguanidines as HIV-1 Protease Inhibitors: Synthesis, Structure−Activity Relationships, and X-ray Crystal Structure Studies

α-Fluoro-substituted thalidomide analogues

Enantioselective Capture and Retroracemization of (1-Bromoalkyl)boronic Esters by an N-Propanoyloxazolidinone Enolate and Iodide Ion

A novel subclass of thalidomide analogue with anti-solid tumor activity in which caspase-dependent apoptosis is associated with altered expression of bcl-2 family proteins

Potent inhibition of cytokine production from intestinal lamina propria T cells by phosphodiesterase-4 inhibitory thalidomide analogues

Effect of 3-fluorothalidomide and 3-methylthalidomide enantiomers on tumor necrosis factor production and antitumor responses to the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)

Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS

Selective cytokine inhibitory drugs with enhanced antiangiogenic activity control tumor growth through vascular inhibition

Hydrolysis of Substituted 1,3,2-Dioxaborolanes and an Asymmetric Synthesis of a Differentially Protected syn,syn-3-Methyl-2,4-hexanediol

Synthesis of 7-membered cyclic oxamides: Novel HIV-1 protease inhibitors

Discovery of (S)-N-{2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide (Apremilast), a Potent and Orally Active Phosphodiesterase 4 and Tumor Necrosis Factor-α Inhibitor

Direct Synthesis of [α-[(tert-Butoxycarbonyl)amino]alkyl]- boronates from (α-Haloalkyl)boronates

High-precision asymmetric synthesis of stegobiol and stegobinone via boronic esters

Protein Degradation via CRL4 CRBN Ubiquitin Ligase: Discovery and Structure-Activity Relationships of Novel Glutarimide Analogs That Promote Degradation of Aiolos and/or GSPT1

Protein Degradation via CRL4CRBN Ubiquitin Ligase: Discovery and Structure–Activity Relationships of Novel Glutarimide Analogs That Promote Degradation of Aiolos and/or GSPT1

Suchergebnisse filtern