UB Paderborn / Katalog / Suche / in CDI

Purine and pyrimidine metabolism in Leishmania

Advances in experimental medicine and biology, 2008, Vol.625, p.141

2008

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Antiparasitic chemotherapy: tinkering with the purine salvage pathway

Advances in experimental medicine and biology, 2008, Vol.625, p.116

2008

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Sterol 14-demethylase inhibitors for Trypanosoma cruzi infections

Advances in experimental medicine and biology, 2008, Vol.625, p.61

Buckner, Frederick S

2008

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Searching the Tritryp genomes for drug targets

Advances in experimental medicine and biology, 2008, Vol.625, p.133

Myler, Peter J

2008

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DNA topoisomerases of Leishmania: the potential targets for anti-leishmanial therapy

Advances in experimental medicine and biology, 2008, Vol.625, p.103

2008

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Selective lead compounds against kinetoplastid tubulin

Advances in experimental medicine and biology, 2008, Vol.625, p.33

2008

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Camptothecin induced mitochondrial dysfunction leading to programmed cell death in unicellular hemoflagellate Leishmania donovani

Cell death and differentiation, 2004-08, Vol.11 (8), p.924-936

2004

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16α‐Hydroxycleroda‐3,13 (14)Z‐dien‐15,16‐olide from Polyalthia longifolia: a safe and orally active antileishmanial agent

British journal of pharmacology, 2010-03, Vol.159 (5), p.1143-1150

2010

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Fishing for anti-leishmania drugs: principles and problems

Advances in experimental medicine and biology, 2008, Vol.625, p.48

2008

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Arsenite resistance in Leishmania and possible drug targets

Advances in experimental medicine and biology, 2008, Vol.625, p.1

2008

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Targeting glycoproteins or glycolipids and their metabolic pathways for antiparasite therapy

Advances in experimental medicine and biology, 2008, Vol.625, p.87

2008

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Unique characteristics of the kinetoplast DNA replication machinery provide potential drug targets in trypanosomatids

Advances in experimental medicine and biology, 2008, Vol.625, p.9

2008

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Camptothecin-induced Imbalance in Intracellular Cation Homeostasis Regulates Programmed Cell Death in Unicellular Hemoflagellate Leishmania donovani

The Journal of biological chemistry, 2004-12, Vol.279 (50), p.52366-52375

2004

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Reconstitution and functional characterization of the unusual bi-subunit type I DNA topoisomerase from Leishmania donovani

FEBS letters, 2004-05, Vol.565 (1), p.81-88

2004

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Differential induction of Leishmania donovani bi-subunit topoisomerase I-DNA cleavage complex by selected flavones and camptothecin: activity of flavones against camptothecin-resistant topoisomerase I

Nucleic acids research, 2006-01, Vol.34 (4), p.1121

2006

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Topoisomerases of kinetoplastid parasites as potential chemotherapeutic targets

Trends in parasitology, 2004-08, Vol.20 (8), p.381-387

2004

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Luteolin, an abundant dietary component is a potent anti-leishmanial agent that acts by inducing topoisomerase II-mediated kinetoplast DNA cleavage leading to apoptosis

Molecular medicine (Cambridge, Mass.), 2000-06, Vol.6 (6), p.527-541

2000

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N-terminal Region of the Large Subunit of Leishmania donovani Bisubunit Topoisomerase I Is Involved in DNA Relaxation and Interaction with the Smaller Subunit

The Journal of biological chemistry, 2005-04, Vol.280 (16), p.16335-16344

2005

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Dihydrobetulinic acid induces apoptosis in Leishmania donovani by targeting DNA topoisomerase I and II: implications in antileishmanial therapy

Molecular medicine (Cambridge, Mass.), 2003-01, Vol.9 (1-2), p.26-36

2003

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Characterization of the ATPase activity of topoisomerase II from Leishmania donovani and identification of residues conferring resistance to etoposide

Biochemical journal, 2005-09, Vol.390 (Pt 2), p.419-426

2005

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Characterisation of the gene encoding type II DNA topoisomerase from Leishmania donovani: a key molecular target in antileishmanial therapy

Nucleic acids research, 2001-05, Vol.29 (9), p.1844

2001

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Functional dissection of the C-terminal domain of type II DNA topoisomerase from the kinetoplastid hemoflagellate Leishmania donovani

Nucleic acids research, 2003-09, Vol.31 (18), p.5305

2003

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16[alpha]-Hydroxycleroda-3,13 (14)Z-dien-15,16-olide from Polyalthia longifolia: a safe and orally active antileishmanial agent

British journal of pharmacology, 2010-03, Vol.159 (5), p.1143

2010

Volltextzugriff (PDF)

Characterization of the DNA-binding domain and identification of the active site residue in the 'Gyr A' half of Leishmania donovani topoisomerase II

Nucleic acids research, 2005-01, Vol.33 (8), p.2364

2005

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DNA topoisomerases in life and death: implications in kinetoplastid protozoa

Current molecular medicine, 2004-09, Vol.4 (6), p.711

2004

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Purine and pyrimidine metabolism in Leishmania

Antiparasitic chemotherapy: tinkering with the purine salvage pathway

Sterol 14-demethylase inhibitors for Trypanosoma cruzi infections

Searching the Tritryp genomes for drug targets

DNA topoisomerases of Leishmania: the potential targets for anti-leishmanial therapy

Selective lead compounds against kinetoplastid tubulin

Camptothecin induced mitochondrial dysfunction leading to programmed cell death in unicellular hemoflagellate Leishmania donovani

16α‐Hydroxycleroda‐3,13 (14)Z‐dien‐15,16‐olide from Polyalthia longifolia: a safe and orally active antileishmanial agent

Fishing for anti-leishmania drugs: principles and problems

Arsenite resistance in Leishmania and possible drug targets

Targeting glycoproteins or glycolipids and their metabolic pathways for antiparasite therapy

Unique characteristics of the kinetoplast DNA replication machinery provide potential drug targets in trypanosomatids

Camptothecin-induced Imbalance in Intracellular Cation Homeostasis Regulates Programmed Cell Death in Unicellular Hemoflagellate Leishmania donovani

Reconstitution and functional characterization of the unusual bi-subunit type I DNA topoisomerase from Leishmania donovani

Differential induction of Leishmania donovani bi-subunit topoisomerase I-DNA cleavage complex by selected flavones and camptothecin: activity of flavones against camptothecin-resistant topoisomerase I

Topoisomerases of kinetoplastid parasites as potential chemotherapeutic targets

Luteolin, an abundant dietary component is a potent anti-leishmanial agent that acts by inducing topoisomerase II-mediated kinetoplast DNA cleavage leading to apoptosis

N-terminal Region of the Large Subunit of Leishmania donovani Bisubunit Topoisomerase I Is Involved in DNA Relaxation and Interaction with the Smaller Subunit

Dihydrobetulinic acid induces apoptosis in Leishmania donovani by targeting DNA topoisomerase I and II: implications in antileishmanial therapy

Characterization of the ATPase activity of topoisomerase II from Leishmania donovani and identification of residues conferring resistance to etoposide

Characterisation of the gene encoding type II DNA topoisomerase from Leishmania donovani: a key molecular target in antileishmanial therapy

Functional dissection of the C-terminal domain of type II DNA topoisomerase from the kinetoplastid hemoflagellate Leishmania donovani

16[alpha]-Hydroxycleroda-3,13 (14)Z-dien-15,16-olide from Polyalthia longifolia: a safe and orally active antileishmanial agent

Characterization of the DNA-binding domain and identification of the active site residue in the 'Gyr A' half of Leishmania donovani topoisomerase II

DNA topoisomerases in life and death: implications in kinetoplastid protozoa

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