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Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy

Nature communications, 2015-02, Vol.6 (1), p.6244-6244, Article 6244

2015

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Spatial preferences of microRNA targets in 3' untranslated regions

BMC genomics, 2007-06, Vol.8 (1), p.152-152

2007

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Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding

Genome research, 2018-09, Vol.28 (9), p.1272-1284

2018

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Orion: Detecting regions of the human non-coding genome that are intolerant to variation using population genetics

PloS one, 2017-08, Vol.12 (8), p.e0181604-e0181604

2017

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Full-length dystrophin restoration via targeted exon integration by AAV-CRISPR in a humanized mouse model of Duchenne muscular dystrophy

Molecular therapy, 2021-11, Vol.29 (11), p.3243-3257

2021

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Direct GR Binding Sites Potentiate Clusters of TF Binding across the Human Genome

Cell, 2016-08, Vol.166 (5), p.1269-1281.e19

2016

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Correction of Dystrophin Expression in Cells From Duchenne Muscular Dystrophy Patients Through Genomic Excision of Exon 51 by Zinc Finger Nucleases

Molecular therapy, 2015-03, Vol.23 (3), p.523-532

2015

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Motif composition, conservation and condition-specificity of single and alternative transcription start sites in the Drosophila genome

Genome biology, 2009-07, Vol.10 (7), p.R73-R73, Article R73

2009

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Efficient Genome-Wide Sequencing and Low-Coverage Pedigree Analysis from Noninvasively Collected Samples

Genetics (Austin), 2016-06, Vol.203 (2), p.699-714

2016

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Human genome-wide measurement of drug-responsive regulatory activity

Nature communications, 2018-12, Vol.9 (1), p.5317-9, Article 5317

2018

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A viral microRNA functions as an orthologue of cellular miR-155

Nature, 2007-12, Vol.450 (7172), p.1096-1099

2007

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Promoter Deletion Leading to Allele Specific Expression in a Genetically Unsolved Case of Primary Ciliary Dyskinesia

American journal of medical genetics. Part A, 2024-10, p.e63880

2024

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Massively parallel quantification of the regulatory effects of noncoding genetic variation in a human cohort

Genome research, 2015-08, Vol.25 (8), p.1206-1214

2015

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Pre-established Chromatin Interactions Mediate the Genomic Response to Glucocorticoids

Cell systems, 2018-08, Vol.7 (2), p.146-160.e7

2018

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Correction: Orion: Detecting regions of the human non-coding genome that are intolerant to variation using population genetics

PloS one, 2018-01, Vol.13 (1), p.e0191298-e0191298

2018

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Predicting gene structure changes resulting from genetic variants via exon definition features

Bioinformatics, 2018-11, Vol.34 (21), p.3616-3623

2018

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Correcting signal biases and detecting regulatory elements in STARR-seq data

Genome research, 2021-05, Vol.31 (5), p.877-889

2021

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Modeling the evolution of regulatory elements by simultaneous detection and alignment with phylogenetic pair HMMs

PLoS computational biology, 2010-12, Vol.6 (12), p.e1001037-e1001037

2010

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MicroRNA target site identification by integrating sequence and binding information

Nature methods, 2013-07, Vol.10 (7), p.630-633

2013

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Bayesian estimation of genetic regulatory effects in high-throughput reporter assays

Bioinformatics, 2020-01, Vol.36 (2), p.331-338

2020

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Improved transcript isoform discovery using ORF graphs

Bioinformatics (Oxford, England), 2014-07, Vol.30 (14), p.1958-1964

2014

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Automated annotation of gene expression image sequences via non-parametric factor analysis and conditional random fields

Bioinformatics, 2013-07, Vol.29 (13), p.i27-i35

2013

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High-throughput interpretation of gene structure changes in human and nonhuman resequencing data, using ACE

Bioinformatics (Oxford, England), 2017-05, Vol.33 (10), p.1437-1446

2017

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Evaluating Chromatin Accessibility Differences Across Multiple Primate Species Using a Joint Modeling Approach

Genome biology and evolution, 2019-10, Vol.11 (10), p.3035-3053

2019

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Genomics and natural language processing

Nature reviews. Genetics, 2002-08, Vol.3 (8), p.601-610

2002

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Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy

Spatial preferences of microRNA targets in 3' untranslated regions

Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding

Orion: Detecting regions of the human non-coding genome that are intolerant to variation using population genetics

Full-length dystrophin restoration via targeted exon integration by AAV-CRISPR in a humanized mouse model of Duchenne muscular dystrophy

Direct GR Binding Sites Potentiate Clusters of TF Binding across the Human Genome

Correction of Dystrophin Expression in Cells From Duchenne Muscular Dystrophy Patients Through Genomic Excision of Exon 51 by Zinc Finger Nucleases

Motif composition, conservation and condition-specificity of single and alternative transcription start sites in the Drosophila genome

Efficient Genome-Wide Sequencing and Low-Coverage Pedigree Analysis from Noninvasively Collected Samples

Human genome-wide measurement of drug-responsive regulatory activity

A viral microRNA functions as an orthologue of cellular miR-155

Promoter Deletion Leading to Allele Specific Expression in a Genetically Unsolved Case of Primary Ciliary Dyskinesia

Massively parallel quantification of the regulatory effects of noncoding genetic variation in a human cohort

Pre-established Chromatin Interactions Mediate the Genomic Response to Glucocorticoids

Correction: Orion: Detecting regions of the human non-coding genome that are intolerant to variation using population genetics

Predicting gene structure changes resulting from genetic variants via exon definition features

Correcting signal biases and detecting regulatory elements in STARR-seq data

Modeling the evolution of regulatory elements by simultaneous detection and alignment with phylogenetic pair HMMs

MicroRNA target site identification by integrating sequence and binding information

Bayesian estimation of genetic regulatory effects in high-throughput reporter assays

Improved transcript isoform discovery using ORF graphs

Automated annotation of gene expression image sequences via non-parametric factor analysis and conditional random fields

High-throughput interpretation of gene structure changes in human and nonhuman resequencing data, using ACE

Evaluating Chromatin Accessibility Differences Across Multiple Primate Species Using a Joint Modeling Approach

Genomics and natural language processing

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