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APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors

Cell reports (Cambridge), 2019-03, Vol.26 (10), p.2651-2666.e6

2019

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Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer

Cell reports. Medicine, 2020-04, Vol.1 (1), p.100007, Article 100007

2020

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Loss of MIG6 Accelerates Initiation and Progression of Mutant Epidermal Growth Factor Receptor-Driven Lung Adenocarcinoma

Cancer discovery, 2015-05, Vol.5 (5), p.534-549

2015

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Novel CDK12/13 Inhibitors AU-15506 and AU-16770 Are Potent Anti-Cancer Agents in EGFR Mutant Lung Adenocarcinoma with and without Osimertinib Resistance

Cancers, 2023-04, Vol.15 (8), p.2263

2023

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Alterations in HLA Class I-Presented Immunopeptidome and Class I-Interactome upon Osimertinib Resistance in EGFR Mutant Lung Adenocarcinoma

Cancers, 2021-10, Vol.13 (19), p.4977

2021

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Alterations in the Global Proteome and Phosphoproteome in Third Generation EGFR TKI Resistance Reveal Drug Targets to Circumvent Resistance

Cancer research (Chicago, Ill.), 2021-06, Vol.81 (11), p.3051-3066

2021

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J-domain Proteins form Binary Complexes with Hsp90 and Ternary Complexes with Hsp90 and Hsp70

Journal of molecular biology, 2023-09, Vol.435 (17), p.168184-168184, Article 168184

2023

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Proteogenomic Analysis Unveils the HLA Class I-Presented Immunopeptidome in Melanoma and EGFR-Mutant Lung Adenocarcinoma

Molecular & cellular proteomics, 2021-01, Vol.20, p.100136-100136, Article 100136

2021

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The small molecule inhibitor NAV-2729 has a complex target profile including multiple ADP-ribosylation factor regulatory proteins

The Journal of biological chemistry, 2023-03, Vol.299 (3), p.102992-102992, Article 102992

2023

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The homeobox transcription factor DUXBL controls exit from totipotency

Nature genetics, 2024-04, Vol.56 (4), p.697-709

2024

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Quantitative Mass Spectrometry to Interrogate Proteomic Heterogeneity in Metastatic Lung Adenocarcinoma and Validate a Novel Somatic Mutation CDK12-G879V[S]

Molecular & cellular proteomics, 2019-04, Vol.18 (4), p.622-641

2019

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SCAMP3 is a mutant EGFR phosphorylation target and a tumor suppressor in lung adenocarcinoma

Oncogene, 2021-05, Vol.40 (18), p.3331-3346

2021

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Distinct, gene-specific effect of heat shock on heat shock factor-1 recruitment and gene expression of CXC chemokine genes

Cytokine (Philadelphia, Pa.), 2011-04, Vol.54 (1), p.61-67

2011

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Genomic profiling of multiple sequentially acquired tumor metastatic sites from an "exceptional responder" lung adenocarcinoma patient reveals extensive genomic heterogeneity and novel somatic variants driving treatment response

Cold Spring Harbor molecular case studies, 2016-11, Vol.2 (6), p.a001263-a001263

2016

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Antitumor Activity and Antioxidant Role of Ichnocarpus frutescens Against Ehrlich Ascites Carcinoma in Swiss Albino Mice

Natural product sciences, 2007-03, Vol.13 (1), p.54-60

2007

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A multi-level study of the effects of glucocorticoids on human T cells

The Journal of immunology (1950), 2023-05, Vol.210 (1_Supplement), p.154-154.08

2023

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Evaluation of hepatoprotective activity of Cassia fistula leaf extract

Journal of ethnopharmacology, 1999-09, Vol.66 (3), p.277-282

1999

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Anti-inflammatory evaluation of Ficus racemosa Linn. leaf extract

Journal of ethnopharmacology, 2000-09, Vol.72 (1), p.87-92

2000

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The Novel ATR Inhibitor Tuvusertib (M1774) Induces Replication Protein Overexpression and Broad Synergy with DNA-targeted Anticancer Drugs

Molecular cancer therapeutics, 2024-07, Vol.23 (7), p.911-923

2024

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Antineoplastic Activity of Crude Saponin Mixture from the Roots of Luffa tuberosa (Roxb.) in Ehrlich Ascites Carcinoma Bearing Mice

Natural product sciences, 2006-12, Vol.12 (4), p.247-253

2006

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Abstract 1438: Integrated proteogenomics utilizing mass spectrometry to identify MHC-associated neopeptides in EGFR mutant lung adenocarcinoma

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.1438-1438

2019

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Evaluation of drug sensitivity and tumor heterogeneity in thoracic cancers using CANScript, a novel ex-vivo tumor platform

Journal of clinical oncology, 2018-05, Vol.36 (15_suppl), p.e24246-e24246

2018

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Abstract 4528: Quantitative mass spectrometry to interrogate proteomic heterogeneity in metastatic lung adenocarcinoma and validate a novel somatic mutation CDK12-G879V

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.4528-4528

2019

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Clonal evolution and osimertinib resistance mechanisms identified by whole exome and transcriptome sequencing in EGFR mutant NSCLC

Journal of clinical oncology, 2019-05, Vol.37 (15_suppl), p.9049-9049

2019

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Abstract 2927: Proteogenomic heterogeneity in metastatic lung adenocarcinoma revealed from rapid/warm autopsy

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.2927-2927

2017

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APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors

Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer

Loss of MIG6 Accelerates Initiation and Progression of Mutant Epidermal Growth Factor Receptor-Driven Lung Adenocarcinoma

Novel CDK12/13 Inhibitors AU-15506 and AU-16770 Are Potent Anti-Cancer Agents in EGFR Mutant Lung Adenocarcinoma with and without Osimertinib Resistance

Alterations in HLA Class I-Presented Immunopeptidome and Class I-Interactome upon Osimertinib Resistance in EGFR Mutant Lung Adenocarcinoma

Alterations in the Global Proteome and Phosphoproteome in Third Generation EGFR TKI Resistance Reveal Drug Targets to Circumvent Resistance

J-domain Proteins form Binary Complexes with Hsp90 and Ternary Complexes with Hsp90 and Hsp70

Proteogenomic Analysis Unveils the HLA Class I-Presented Immunopeptidome in Melanoma and EGFR-Mutant Lung Adenocarcinoma

The small molecule inhibitor NAV-2729 has a complex target profile including multiple ADP-ribosylation factor regulatory proteins

The homeobox transcription factor DUXBL controls exit from totipotency

Quantitative Mass Spectrometry to Interrogate Proteomic Heterogeneity in Metastatic Lung Adenocarcinoma and Validate a Novel Somatic Mutation CDK12-G879V[S]

SCAMP3 is a mutant EGFR phosphorylation target and a tumor suppressor in lung adenocarcinoma

Distinct, gene-specific effect of heat shock on heat shock factor-1 recruitment and gene expression of CXC chemokine genes

Genomic profiling of multiple sequentially acquired tumor metastatic sites from an "exceptional responder" lung adenocarcinoma patient reveals extensive genomic heterogeneity and novel somatic variants driving treatment response

Antitumor Activity and Antioxidant Role of Ichnocarpus frutescens Against Ehrlich Ascites Carcinoma in Swiss Albino Mice

A multi-level study of the effects of glucocorticoids on human T cells

Evaluation of hepatoprotective activity of Cassia fistula leaf extract

Anti-inflammatory evaluation of Ficus racemosa Linn. leaf extract

The Novel ATR Inhibitor Tuvusertib (M1774) Induces Replication Protein Overexpression and Broad Synergy with DNA-targeted Anticancer Drugs

Antineoplastic Activity of Crude Saponin Mixture from the Roots of Luffa tuberosa (Roxb.) in Ehrlich Ascites Carcinoma Bearing Mice

Abstract 1438: Integrated proteogenomics utilizing mass spectrometry to identify MHC-associated neopeptides in EGFR mutant lung adenocarcinoma

Evaluation of drug sensitivity and tumor heterogeneity in thoracic cancers using CANScript, a novel ex-vivo tumor platform

Abstract 4528: Quantitative mass spectrometry to interrogate proteomic heterogeneity in metastatic lung adenocarcinoma and validate a novel somatic mutation CDK12-G879V

Clonal evolution and osimertinib resistance mechanisms identified by whole exome and transcriptome sequencing in EGFR mutant NSCLC

Abstract 2927: Proteogenomic heterogeneity in metastatic lung adenocarcinoma revealed from rapid/warm autopsy

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