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Preclinical stroke research – advantages and disadvantages of the most common rodent models of focal ischaemia

British journal of pharmacology, 2011-10, Vol.164 (4), p.1062-1078

Macrae, IM

2011

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Estrogen as a Neuroprotectant in Stroke

Journal of Cerebral Blood Flow & Metabolism, 2000-04, Vol.20 (4), p.631-652

2000

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Neuroprotection by a selective estrogen receptor beta agonist in a mouse model of global ischemia

American journal of physiology. Heart and circulatory physiology, 2004-10, Vol.287 (4), p.H1501-H1504

2004

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Brain aromatase expression after experimental stroke: Topography and time course

The Journal of steroid biochemistry and molecular biology, 2005-06, Vol.96 (1), p.89-91

2005

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Antioxidant ebselen reduces oxidative damage in focal cerebral ischemia

Free radical biology & medicine, 2003, Vol.34 (1), p.56-63

2003

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Detrimental Effects of 17β-Oestradiol after Permanent Middle Cerebral Artery Occlusion

Journal of cerebral blood flow and metabolism, 2005-03, Vol.25 (3), p.414-420

2005

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Effects of 17β-oestradiol on cerebral ischaemic damage and lipid peroxidation

Brain research, 2005-03, Vol.1036 (1), p.155-162

2005

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Estrogen Is Neuroprotective via an Apolipoprotein E-Dependent Mechanism in a Mouse Model of Global Ischemia

Journal of cerebral blood flow and metabolism, 2002-10, Vol.22 (10), p.1189-1195

2002

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Proof of concept and feasibility studies examining the influence of combination ribose, adenine and allopurinol treatment on stroke outcome in the rat

Brain and neuroscience advances, 2017-01, Vol.1, p.2398212817717112-2398212817717112

2017

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Differential Effects of 17β-Estradiol Upon Stroke Damage in Stroke Prone and Normotensive Rats

Journal of cerebral blood flow and metabolism, 2004-03, Vol.24 (3), p.298-304

2004

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Impaired functional recovery after stroke in the stroke-prone spontaneously hypertensive rat

Stroke (1970), 2005, Vol.36 (1), p.135-141

2005

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Influence of Ischemia and Reperfusion on the Course of Brain Tissue Swelling and Blood–Brain Barrier Permeability in a Rodent Model of Transient Focal Cerebral Ischemia

Experimental neurology, 1997-10, Vol.147 (2), p.353-360

1997

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Neuroprotective efficacy of ebselen, an anti-oxidant with antiinflammatory actions, in a rodent model of permanent middle cerebral artery occlusion

British journal of pharmacology, 1997-11, Vol.122 (6), p.1251-1256

1997

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Estrogen status affects sensitivity to focal cerebral ischemia in stroke-prone spontaneously hypertensive rats

American journal of physiology. Heart and circulatory physiology, 2000-01, Vol.278 (1), p.H290-H294

2000

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Sensitivity to cerebral ischaemic insult in a rat model of stroke is determined by a single genetic locus

Nature genetics, 1997-08, Vol.16 (4), p.364-367

1997

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Evolution of GADD34 expression after focal cerebral ischaemia

Brain research, 2005-02, Vol.1034 (1), p.51-61

2005

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Specific expression of the cell cycle regulation proteins, GADD34 and PCNA, in the peri-infarct zone after focal cerebral ischaemia in the rat

The European journal of neuroscience, 2002-06, Vol.15 (12), p.1929-1936

2002

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New Method for the Quantitative Assessment of Axonal Damage in Focal Cerebral Ischemia

Journal of cerebral blood flow and metabolism, 2002-09, Vol.22 (9), p.1080-1089

2002

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Characterization of the Microglial Response to Cerebral Ischemia in the Stroke-Prone Spontaneously Hypertensive Rat

Hypertension (Dallas, Tex. 1979), 2001-07, Vol.38 (1), p.116-122

2001

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Endothelin-1-induced reductions in cerebral blood flow: dose dependency, time course, and neuropathological consequences

Journal of cerebral blood flow and metabolism, 1993-03, Vol.13 (2), p.276-284

1993

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Identification of the growth arrest and DNA damage protein GADD34 in the normal human heart and demonstration of alterations in expression following myocardial ischaemia

International journal of cardiology, 2006-02, Vol.107 (1), p.126-129

2006

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Up-regulation of a growth arrest and DNA damage protein (GADD34) in the ischaemic human brain: implications for protein synthesis regulation and DNA repair

Neuropathology and applied neurobiology, 2004-12, Vol.30 (6), p.683-691

2004

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Genetic and Gender Influences on Sensitivity to Focal Cerebral Ischemia in the Stroke-Prone Spontaneously Hypertensive Rat

Hypertension (Dallas, Tex. 1979), 1999-02, Vol.33 (2), p.681-685

1999

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Investigation of Estrogen Status and Increased Stroke Sensitivity on Cerebral Blood Flow After a Focal Ischemic Insult

Journal of cerebral blood flow and metabolism, 2000-06, Vol.20 (6), p.931-936

2000

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Increased Levels of Superoxide in Brains from Old Female Rats

Free radical research, 2004-02, Vol.38 (2), p.177-183

2004

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Preclinical stroke research – advantages and disadvantages of the most common rodent models of focal ischaemia

Estrogen as a Neuroprotectant in Stroke

Neuroprotection by a selective estrogen receptor beta agonist in a mouse model of global ischemia

Brain aromatase expression after experimental stroke: Topography and time course

Antioxidant ebselen reduces oxidative damage in focal cerebral ischemia

Detrimental Effects of 17β-Oestradiol after Permanent Middle Cerebral Artery Occlusion

Effects of 17β-oestradiol on cerebral ischaemic damage and lipid peroxidation

Estrogen Is Neuroprotective via an Apolipoprotein E-Dependent Mechanism in a Mouse Model of Global Ischemia

Proof of concept and feasibility studies examining the influence of combination ribose, adenine and allopurinol treatment on stroke outcome in the rat

Differential Effects of 17β-Estradiol Upon Stroke Damage in Stroke Prone and Normotensive Rats

Impaired functional recovery after stroke in the stroke-prone spontaneously hypertensive rat

Influence of Ischemia and Reperfusion on the Course of Brain Tissue Swelling and Blood–Brain Barrier Permeability in a Rodent Model of Transient Focal Cerebral Ischemia

Neuroprotective efficacy of ebselen, an anti-oxidant with antiinflammatory actions, in a rodent model of permanent middle cerebral artery occlusion

Estrogen status affects sensitivity to focal cerebral ischemia in stroke-prone spontaneously hypertensive rats

Sensitivity to cerebral ischaemic insult in a rat model of stroke is determined by a single genetic locus

Evolution of GADD34 expression after focal cerebral ischaemia

Specific expression of the cell cycle regulation proteins, GADD34 and PCNA, in the peri-infarct zone after focal cerebral ischaemia in the rat

New Method for the Quantitative Assessment of Axonal Damage in Focal Cerebral Ischemia

Characterization of the Microglial Response to Cerebral Ischemia in the Stroke-Prone Spontaneously Hypertensive Rat

Endothelin-1-induced reductions in cerebral blood flow: dose dependency, time course, and neuropathological consequences

Identification of the growth arrest and DNA damage protein GADD34 in the normal human heart and demonstration of alterations in expression following myocardial ischaemia

Up-regulation of a growth arrest and DNA damage protein (GADD34) in the ischaemic human brain: implications for protein synthesis regulation and DNA repair

Genetic and Gender Influences on Sensitivity to Focal Cerebral Ischemia in the Stroke-Prone Spontaneously Hypertensive Rat

Investigation of Estrogen Status and Increased Stroke Sensitivity on Cerebral Blood Flow After a Focal Ischemic Insult

Increased Levels of Superoxide in Brains from Old Female Rats

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