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Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: has the time come?

British journal of pharmacology, 2017-11, Vol.174 (21), p.3749-3765

2017

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Perspectives on the Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Biomedical Research

Stem cell reports, 2018-12, Vol.11 (6), p.1306-1311

Mummery, Christine L.

2018

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Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells

Development (Cambridge), 2017-03, Vol.144 (6), p.1008-1017

2017

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Advanced in vitro models of vascular biology: Human induced pluripotent stem cells and organ-on-chip technology

Advanced drug delivery reviews, 2019-02, Vol.140, p.68-77

2019

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Immaturity of human stem-cell-derived cardiomyocytes in culture: fatal flaw or soluble problem?

Stem cells and development, 2015-05, Vol.24 (9), p.1035-1052

2015

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Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells

Nature protocols, 2014-06, Vol.9 (6), p.1514-1531

2014

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Inherited heart disease – what can we expect from the second decade of human iPS cell research?

FEBS letters, 2016-08, Vol.590 (15), p.2482-2493

2016

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Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure

European heart journal, 2016-06, Vol.37 (23), p.1789-1798

2016

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Functional maturation of human pluripotent stem cell derived cardiomyocytes in vitro – Correlation between contraction force and electrophysiology

Biomaterials, 2015-05, Vol.51, p.138-150

2015

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Stem-cell-based therapy and lessons from the heart

Nature (London), 2008-05, Vol.453 (7193), p.322-329

2008

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Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes

Nature communications, 2019-09, Vol.10 (1), p.4325-9, Article 4325

2019

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Contractile Defect Caused by Mutation in MYBPC3 Revealed under Conditions Optimized for Human PSC-Cardiomyocyte Function

Cell reports (Cambridge), 2015-10, Vol.13 (4), p.733-745

2015

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Functionality of endothelial cells and pericytes from human pluripotent stem cells demonstrated in cultured vascular plexus and zebrafish xenografts

Arteriosclerosis, thrombosis, and vascular biology, 2014-01, Vol.34 (1), p.177-186

2014

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Expansion and patterning of cardiovascular progenitors derived from human pluripotent stem cells

Nature biotechnology, 2015-09, Vol.33 (9), p.970-979

2015

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Atrial‐like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial‐selective pharmacology

EMBO molecular medicine, 2015-04, Vol.7 (4), p.394-410

2015

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Concise Review: Measuring Physiological Responses of Human Pluripotent Stem Cell Derived Cardiomyocytes to Drugs and Disease

Stem cells (Dayton, Ohio), 2016-08, Vol.34 (8), p.2008-2015

2016

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Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: Disease mechanisms and pharmacological rescue

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (50), p.17707-17707

2014

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Three-dimensional co-cultures of human endothelial cells and embryonic stem cell-derived pericytes inside a microfluidic device

Lab on a chip, 2013-09, Vol.13 (18), p.3562-3568

2013

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A Miniaturized EHT Platform for Accurate Measurements of Tissue Contractile Properties

Journal of microelectromechanical systems, 2020-10, Vol.29 (5), p.881-887

2020

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Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes

Toxicological sciences, 2020-07, Vol.176 (1), p.103-123

2020

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Differentiation and Functional Comparison of Monocytes and Macrophages from hiPSCs with Peripheral Blood Derivatives

Stem cell reports, 2019-06, Vol.12 (6), p.1282-1297

2019

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Stalk Cell Phenotype Depends on Integration of Notch and Smad1/5 Signaling Cascades

Developmental cell, 2012-03, Vol.22 (3), p.501-514

2012

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Cardiomyocyte differentiation of pluripotent stem cells and their use as cardiac disease models

Biochemical journal, 2011-02, Vol.434 (1), p.25-35

2011

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Cardiomyocytes Derived From Pluripotent Stem Cells Recapitulate Electrophysiological Characteristics of an Overlap Syndrome of Cardiac Sodium Channel Disease

Circulation (New York, N.Y.), 2012-06, Vol.125 (25), p.3079-3091

2012

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Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytes

Stem cell research, 2010-03, Vol.4 (2), p.107-116

2010

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Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: has the time come?

Perspectives on the Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Biomedical Research

Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells

Advanced in vitro models of vascular biology: Human induced pluripotent stem cells and organ-on-chip technology

Immaturity of human stem-cell-derived cardiomyocytes in culture: fatal flaw or soluble problem?

Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells

Inherited heart disease – what can we expect from the second decade of human iPS cell research?

Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure

Functional maturation of human pluripotent stem cell derived cardiomyocytes in vitro – Correlation between contraction force and electrophysiology

Stem-cell-based therapy and lessons from the heart

Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes

Contractile Defect Caused by Mutation in MYBPC3 Revealed under Conditions Optimized for Human PSC-Cardiomyocyte Function

Functionality of endothelial cells and pericytes from human pluripotent stem cells demonstrated in cultured vascular plexus and zebrafish xenografts

Expansion and patterning of cardiovascular progenitors derived from human pluripotent stem cells

Atrial‐like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial‐selective pharmacology

Concise Review: Measuring Physiological Responses of Human Pluripotent Stem Cell Derived Cardiomyocytes to Drugs and Disease

Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: Disease mechanisms and pharmacological rescue

Three-dimensional co-cultures of human endothelial cells and embryonic stem cell-derived pericytes inside a microfluidic device

A Miniaturized EHT Platform for Accurate Measurements of Tissue Contractile Properties

Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes

Differentiation and Functional Comparison of Monocytes and Macrophages from hiPSCs with Peripheral Blood Derivatives

Stalk Cell Phenotype Depends on Integration of Notch and Smad1/5 Signaling Cascades

Cardiomyocyte differentiation of pluripotent stem cells and their use as cardiac disease models

Cardiomyocytes Derived From Pluripotent Stem Cells Recapitulate Electrophysiological Characteristics of an Overlap Syndrome of Cardiac Sodium Channel Disease

Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytes

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