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New pyrazolo[3,4- d]pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (10), p.2511-2517

2004

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Ionization behaviour and tautomerism-dependent lipophilicity of pyridine-2(1H)-one cardiotonic agents

Bioorganic & medicinal chemistry, 2000-05, Vol.8 (5), p.909-916

2000

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Pyrazolo[3,4-d]pyrimidines as Potent Antiproliferative and Proapoptotic Agents toward A431 and 8701-BC Cells in Culture via Inhibition of c-Src Phosphorylation

Journal of medicinal chemistry, 2006-03, Vol.49 (5), p.1549-1561

2006

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An Efficient Synthesis of Functionalized 2-Pyridones by Direct Route or via Amide/Enolate Ammonium Salt Intermediates

Synthesis (Stuttgart), 1999-07, Vol.1999 (7), p.1169-1174

Bondavalli, Francesco

1999

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New milrinone analogues: in vitro study of structure-activity relationships for positive inotropic effect, antagonism towards endogenous adenosine, and inhibition of cardiac type III phosphodiesterase

Naunyn-Schmiedeberg's archives of pharmacology, 2003-02, Vol.367 (2), p.109-118

2003

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Synthesis, antimicrobial activity and molecular modeling studies of halogenated 4-[1H-imidazol-1-yl(phenyl)methyl]- 1,5-diphenyl-1H-pyrazoles

Bioorganic & medicinal chemistry, 2004-10, Vol.12 (20), p.5465-5483

2004

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Antiproliferative activity of new 1-aryl-4-amino-1H-pyrazolo[3,4-d]pyrimidine derivatives toward the human epidermoid carcinoma A431 cell line

European journal of medicinal chemistry, 2004-11, Vol.39 (11), p.939-946

2004

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Synthesis and In Vitro Antiplatelet Activity of New 4-(1-Piperazinyl)coumarin Derivatives. Human Platelet Phosphodiesterase 3 Inhibitory Properties of the Two Most Effective Compounds Described and Molecular Modeling Study on Their Interactions with Phosphodiesterase 3A Catalytic Site

Journal of medicinal chemistry, 2007-06, Vol.50 (12), p.2886-2895

2007

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Synthesis and pharmacological characterization of functionalized 2-pyridones structurally related to the cardiotonic agent milrinone

Bioorganic & medicinal chemistry, 2003-11, Vol.11 (22), p.4749-4759

2003

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Structure-Based Design, Parallel Synthesis, Structure−Activity Relationship, and Molecular Modeling Studies of Thiocarbamates, New Potent Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitor Isosteres of Phenethylthiazolylthiourea Derivatives

Journal of medicinal chemistry, 2005-06, Vol.48 (11), p.3858-3873

2005

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Novel angular furo and thieno-quinolinones: synthesis and preliminary photobiological studies

Bioorganic & medicinal chemistry, 2002-03, Vol.10 (3), p.743-751

2002

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Insights into structure–activity relationships from lipophilicity profiles of pyridin-2(1 H)-one analogs of the cardiotonic agent milrinone

European journal of pharmaceutical sciences, 2005-09, Vol.26 (1), p.78-86

2005

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A pharmacological, crystallographic, and quantum chemical study of new inotropic agents

Journal of medicinal chemistry, 1993-08, Vol.36 (17), p.2475-2484

1993

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Pyrazolo[3,4-d]pyrimidines Endowed with Antiproliferative Activity on Ductal Infiltrating Carcinoma Cells

Journal of medicinal chemistry, 2004-03, Vol.47 (7), p.1595-1598

2004

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Synthesis, biological evaluation and molecular modelling studies on benzothiadiazine derivatives as PDE4 selective inhibitors

Bioorganic & medicinal chemistry, 2005-02, Vol.13 (4), p.1393-1402

2005

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Synthesis of 1-(2-chloro-2-phenylethyl)-6-methylthio-1H-pyrazolo[3,4-d]pyrimidines 4-amino substituted and their biological evaluation

European journal of medicinal chemistry, 2004-02, Vol.39 (2), p.153-160

2004

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ω-Dialkylaminoalkyl ethers of phenyl-(5-substituted 1-phenyl-1H-pyrazol-4-yl)methanols with analgesic and anti-inflammatory activity

Journal of heterocyclic chemistry, 1997-05, Vol.34 (3), p.963-968

1997

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Conformational analysis and inotropic activity of 2-substituted-5-cyano-1,6-dihydro-6-oxo-3-pyridine carboxylates. II

European journal of medicinal chemistry, 1993, Vol.28 (7), p.637-641

1993

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Cardiotonic agents: a crystallographic and quantum-chemical study of ethyl 5-cyano-1,6-dihydro-2-isopropyl-6-oxo-3-pyridine carboxylate and related compounds

European journal of medicinal chemistry, 1990-06, Vol.25 (5), p.425-431

1990

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Inotropic agents. Synthesis and structure-activity relationships of new milrinone related cAMP PDE III inhibitors

Farmaco (Società chimica italiana : 1989), 1997-08, Vol.52 (8-9), p.523

1997

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Synthesis and cardiotonic activity of esters of 2-substituted 5-acetyl-1,6-dihydro-6-oxo-3-pyridinecarboxylic acids

European journal of medicinal chemistry, 1993, Vol.28 (11), p.853-858

1993

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New pyrazolo[3,4-b]pyridones as selective A(1) adenosine receptor antagonists: synthesis, biological evaluation and molecular modelling studies

Organic & biomolecular chemistry, 2005-06, Vol.3 (12), p.2262-2270

2005

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In silico rationalization of the structural and physicochemical requirements for photobiological activity in angelicine derivatives and their heteroanalogues

Journal of computer-aided molecular design, 2003-01, Vol.17 (1), p.53

2003

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Antiviral activity of FA-11H on the infectivity and replication of herpes simplex virus type 1 in cultured cells

The New microbiologica, 1998-07, Vol.21 (3), p.275

1998

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Synthesis and biological data of 4-amino-1-(2-chloro-2-phenylethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl esters, a new series of a1-adenosine receptor (A1AR) ligands

Bioorganic & medicinal chemistry letters, 2001-09, Vol.11 (18), p.2529-2531

2001

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New pyrazolo[3,4- d]pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation

Ionization behaviour and tautomerism-dependent lipophilicity of pyridine-2(1H)-one cardiotonic agents

Pyrazolo[3,4-d]pyrimidines as Potent Antiproliferative and Proapoptotic Agents toward A431 and 8701-BC Cells in Culture via Inhibition of c-Src Phosphorylation

An Efficient Synthesis of Functionalized 2-Pyridones by Direct Route or via Amide/Enolate Ammonium Salt Intermediates

New milrinone analogues: in vitro study of structure-activity relationships for positive inotropic effect, antagonism towards endogenous adenosine, and inhibition of cardiac type III phosphodiesterase

Synthesis, antimicrobial activity and molecular modeling studies of halogenated 4-[1H-imidazol-1-yl(phenyl)methyl]- 1,5-diphenyl-1H-pyrazoles

Antiproliferative activity of new 1-aryl-4-amino-1H-pyrazolo[3,4-d]pyrimidine derivatives toward the human epidermoid carcinoma A431 cell line

Synthesis and In Vitro Antiplatelet Activity of New 4-(1-Piperazinyl)coumarin Derivatives. Human Platelet Phosphodiesterase 3 Inhibitory Properties of the Two Most Effective Compounds Described and Molecular Modeling Study on Their Interactions with Phosphodiesterase 3A Catalytic Site

Synthesis and pharmacological characterization of functionalized 2-pyridones structurally related to the cardiotonic agent milrinone

Structure-Based Design, Parallel Synthesis, Structure−Activity Relationship, and Molecular Modeling Studies of Thiocarbamates, New Potent Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitor Isosteres of Phenethylthiazolylthiourea Derivatives

Novel angular furo and thieno-quinolinones: synthesis and preliminary photobiological studies

Insights into structure–activity relationships from lipophilicity profiles of pyridin-2(1 H)-one analogs of the cardiotonic agent milrinone

A pharmacological, crystallographic, and quantum chemical study of new inotropic agents

Pyrazolo[3,4-d]pyrimidines Endowed with Antiproliferative Activity on Ductal Infiltrating Carcinoma Cells

Synthesis, biological evaluation and molecular modelling studies on benzothiadiazine derivatives as PDE4 selective inhibitors

Synthesis of 1-(2-chloro-2-phenylethyl)-6-methylthio-1H-pyrazolo[3,4-d]pyrimidines 4-amino substituted and their biological evaluation

ω-Dialkylaminoalkyl ethers of phenyl-(5-substituted 1-phenyl-1H-pyrazol-4-yl)methanols with analgesic and anti-inflammatory activity

Conformational analysis and inotropic activity of 2-substituted-5-cyano-1,6-dihydro-6-oxo-3-pyridine carboxylates. II

Cardiotonic agents: a crystallographic and quantum-chemical study of ethyl 5-cyano-1,6-dihydro-2-isopropyl-6-oxo-3-pyridine carboxylate and related compounds

Inotropic agents. Synthesis and structure-activity relationships of new milrinone related cAMP PDE III inhibitors

Synthesis and cardiotonic activity of esters of 2-substituted 5-acetyl-1,6-dihydro-6-oxo-3-pyridinecarboxylic acids

New pyrazolo[3,4-b]pyridones as selective A(1) adenosine receptor antagonists: synthesis, biological evaluation and molecular modelling studies

In silico rationalization of the structural and physicochemical requirements for photobiological activity in angelicine derivatives and their heteroanalogues

Antiviral activity of FA-11H on the infectivity and replication of herpes simplex virus type 1 in cultured cells

Synthesis and biological data of 4-amino-1-(2-chloro-2-phenylethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl esters, a new series of a1-adenosine receptor (A1AR) ligands

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