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Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer

European urology, 2016-04, Vol.69 (4), p.646-657

2016

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High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq

Blood, 2011-06, Vol.117 (23), p.e207-e217

2011

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No evidence for high-pressure melting of Earth's crust in the Archean

Nature communications, 2019-12, Vol.10 (1), p.5559-12, Article 5559

2019

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Hypoxic Regulation of Gene Transcription and Chromatin: Cause and Effect

International journal of molecular sciences, 2020-11, Vol.21 (21), p.8320

2020

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Oxygen isotopes trace the origins of Earth's earliest continental crust

Nature (London), 2021-04, Vol.592 (7852), p.70-75

2021

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Hypoxic regulation of the noncoding genome and NEAT1

Briefings in functional genomics, 2016-05, Vol.15 (3), p.174-185

2016

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Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases

The Journal of biological chemistry, 2016-09, Vol.291 (39), p.20661-20673

2016

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The HIF complex recruits the histone methyltransferase SET1B to activate specific hypoxia-inducible genes

Nature genetics, 2021-07, Vol.53 (7), p.1022-1035

2021

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Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter

Journal of hepatology, 2021-07, Vol.75 (1), p.64-73

2021

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Archean komatiite volcanism controlled by the evolution of early continents

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (28), p.10083-10088

2014

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Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer

Nature communications, 2016-10, Vol.7 (1), p.13183-13183, Article 13183

2016

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Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression

Nature genetics, 2012-04, Vol.44 (4), p.420-425

2012

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Multiple renal cancer susceptibility polymorphisms modulate the HIF pathway

PLoS genetics, 2017-07, Vol.13 (7), p.e1006872-e1006872

2017

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Case report of oxalate nephropathy in a patient with pancreatic metastases from renal carcinoma

BMC cancer, 2019-10, Vol.19 (1), p.967-6, Article 967

2019

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Iron homeostasis and its interaction with prolyl hydroxylases

Antioxidants & redox signaling, 2010-02, Vol.12 (4), p.445

Mole, David R

2010

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Regulation of growth differentiation factor 15 expression by intracellular iron

Blood, 2009-02, Vol.113 (7), p.1555-1563

2009

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Inherent DNA‐binding specificities of the HIF‐1α and HIF‐2α transcription factors in chromatin

EMBO reports, 2019-01, Vol.20 (1), p.n/a

2019

Volltextzugriff (PDF)

Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts

The Journal of biological chemistry, 2009-06, Vol.284 (25), p.16767-16775

2009

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Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature

Cell reports (Cambridge), 2022-11, Vol.41 (7), p.111652-111652, Article 111652

2022

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Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2

EMBO reports, 2014-01, Vol.15 (1), p.70-76

2014

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Determination and comparison of specific activity of the HIF-prolyl hydroxylases

FEBS letters, 2004-10, Vol.576 (1), p.145-150

2004

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MITF controls the TCA cycle to modulate the melanoma hypoxia response

Pigment cell and melanoma research, 2019-11, Vol.32 (6), p.792-808

2019

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Lysyl Oxidases LOX and LOXL2 Are Necessary and Sufficient to Repress E-cadherin in Hypoxia: INSIGHTS INTO CELLULAR TRANSFORMATION PROCESSES MEDIATED BY HIF-1

The Journal of biological chemistry, 2010-02, Vol.285 (9), p.6658-6669

2010

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Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1α

Biochemical journal, 2008-12, Vol.416 (3), p.387-394

2008

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Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)–mediated induction of the long noncoding RNA NICI

The Journal of biological chemistry, 2020-03, Vol.295 (13), p.4065-4078

2020

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Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer

High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq

No evidence for high-pressure melting of Earth's crust in the Archean

Hypoxic Regulation of Gene Transcription and Chromatin: Cause and Effect

Oxygen isotopes trace the origins of Earth's earliest continental crust

Hypoxic regulation of the noncoding genome and NEAT1

Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases

The HIF complex recruits the histone methyltransferase SET1B to activate specific hypoxia-inducible genes

Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter

Archean komatiite volcanism controlled by the evolution of early continents

Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer

Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression

Multiple renal cancer susceptibility polymorphisms modulate the HIF pathway

Case report of oxalate nephropathy in a patient with pancreatic metastases from renal carcinoma

Iron homeostasis and its interaction with prolyl hydroxylases

Regulation of growth differentiation factor 15 expression by intracellular iron

Inherent DNA‐binding specificities of the HIF‐1α and HIF‐2α transcription factors in chromatin

Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts

Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature

Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2

Determination and comparison of specific activity of the HIF-prolyl hydroxylases

MITF controls the TCA cycle to modulate the melanoma hypoxia response

Lysyl Oxidases LOX and LOXL2 Are Necessary and Sufficient to Repress E-cadherin in Hypoxia: INSIGHTS INTO CELLULAR TRANSFORMATION PROCESSES MEDIATED BY HIF-1

Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1α

Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)–mediated induction of the long noncoding RNA NICI

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