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New dual inhibitors of EGFR and HER2 protein tyrosine kinases

Bioorganic & medicinal chemistry letters, 2005-11, Vol.15 (21), p.4774-4779

2005

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Discovery of the Pyrrolo[2,1-f][1,2,4]triazine Nucleus as a New Kinase Inhibitor Template

Journal of medicinal chemistry, 2004-07, Vol.47 (16), p.4054-4059

2004

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Discovery of Aminothiazole Inhibitors of Cyclin-Dependent Kinase 2: Synthesis, X-ray Crystallographic Analysis, and Biological Activities

Journal of medicinal chemistry, 2002-08, Vol.45 (18), p.3905-3927

2002

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A Practical Asymmetric Synthesis of the Antiviral Agent Lobucavir, BMS-180194

Organic process research & development, 1998-11, Vol.2 (6), p.393-399

1998

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Synthesis and antiviral activity of enantiomeric forms of cyclobutyl nucleoside analogs

Journal of medicinal chemistry, 1991-04, Vol.34 (4), p.1415-1421

1991

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Discovery of (R)-7-Cyano-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine (BMS-214662), a Farnesyltransferase Inhibitor with Potent Preclinical Antitumor Activity

Journal of medicinal chemistry, 2000-10, Vol.43 (20), p.3587-3595

2000

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Novel guanidine-based inhibitors of inosine monophosphate dehydrogenase

Bioorganic & medicinal chemistry letters, 2002-10, Vol.12 (20), p.2931-2934

2002

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Discovery and Structure−Activity Relationships of Imidazole-Containing Tetrahydrobenzodiazepine Inhibitors of Farnesyltransferase

Journal of medicinal chemistry, 1999-12, Vol.42 (25), p.5241-5253

1999

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Regioselective Coupling of Tetraalkylammonium Salts of 6-Iodo-2-aminopurine to a Cyclobutyl Triflate: Efficient Preparation of Homochiral BMS-180,194, a Potent Antiviral Carbocyclic Nucleoside

Journal of organic chemistry, 1995-05, Vol.60 (9), p.2902-2905

1995

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Aminodiol HIV protease inhibitors. 1. Design, synthesis, and preliminary SAR

Journal of medicinal chemistry, 1994-06, Vol.37 (12), p.1758-1768

1994

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Discovery of ( R )-7-Cyano-2,3,4,5-tetrahydro-1-(1 H -imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1 H -1,4-benzodiazepine (BMS-214662), a Farnesyltransferase Inhibitor with Potent Preclinical Antitumor Activity

Journal of medicinal chemistry, 2000-10, Vol.43 (20), p.3587-3595

2000

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2023 ESC Guidelines for the management of acute coronary syndromes

European heart journal, 2023-10, Vol.44 (38), p.3720-3826

2023

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Synthesis of cinchona alkaloids via quinuclidine precursors

Journal of the American Chemical Society, 1971-11, Vol.93 (22), p.5904-5907

1971

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Discovery and Structure−Activity Relationships of Imidazole-Containing Tetrahydrobenzodiazepine Inhibitors of Farnesyltransferase

Journal of medicinal chemistry, 1999-12, Vol.42 (25), p.5288-5288

1999

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A Practical Asymmetric Synthesis of the Antiviral Agent Lobucavir, BMS-180194

Organic process research & development, 1999-05, Vol.3 (3), p.235-235

1999

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α-hydroxyamide derived aminodiols as potent inhibitors of hiv protease

Bioorganic & medicinal chemistry letters, 1995-08, Vol.5 (15), p.1729-1734

1995

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Total synthesis of pseudomonic acid C

Journal of organic chemistry, 1988-09, Vol.53 (18), p.4282-4295

1988

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Synthesis of daunosamine

Journal of organic chemistry, 1983-12, Vol.48 (26), p.5309-5315

1983

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Total synthesis of Cinchona alkaloids. 4. Syntheses via quinuclidine precursors

Journal of the American Chemical Society, 1978-01, Vol.100 (2), p.589-593

1978

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Total synthesis of Cinchona alkaloids. 3. Syntheses of quinuclidine intermediates

Journal of the American Chemical Society, 1978-01, Vol.100 (2), p.581-588

1978

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Reinvestigation of the classical synthesis of Cinchona alkaloids. I. A new synthesis of homomeroquinene and quinotoxine

Helvetica chimica acta, 1973-07, Vol.56 (5), p.1485-1494

1973

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ChemInform Abstract: REINVESTIGATION OF THE CLASSICAL SYNTHESIS OF CINCHONA ALKALOIDS PART 1, A NEW SYNTHESIS OF HOMOMEXOQUINENE AND QUINOTOXINE

Chemischer Informationsdienst, 1973-09, Vol.4 (39)

1973

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ChemInform Abstract: SYNTH. VON CINCHONA‐ALKALOIDEN UEBER CHINUCLIDIN‐VORLAEUFER

Chemischer Informationsdienst, 1972-01, Vol.3 (3)

1972

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A Selective Sweep on a Deleterious Mutation in CPT1A in Arctic Populations

American journal of human genetics, 2014-11, Vol.95 (5), p.584-589

2014

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Evidence of Early-Stage Selection on EPAS1 and GPR126 Genes in Andean High Altitude Populations

Scientific reports, 2017-10, Vol.7 (1), p.13042-9, Article 13042

2017

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New dual inhibitors of EGFR and HER2 protein tyrosine kinases

Discovery of the Pyrrolo[2,1-f][1,2,4]triazine Nucleus as a New Kinase Inhibitor Template

Discovery of Aminothiazole Inhibitors of Cyclin-Dependent Kinase 2: Synthesis, X-ray Crystallographic Analysis, and Biological Activities

A Practical Asymmetric Synthesis of the Antiviral Agent Lobucavir, BMS-180194

Synthesis and antiviral activity of enantiomeric forms of cyclobutyl nucleoside analogs

Discovery of (R)-7-Cyano-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine (BMS-214662), a Farnesyltransferase Inhibitor with Potent Preclinical Antitumor Activity

Novel guanidine-based inhibitors of inosine monophosphate dehydrogenase

Discovery and Structure−Activity Relationships of Imidazole-Containing Tetrahydrobenzodiazepine Inhibitors of Farnesyltransferase

Regioselective Coupling of Tetraalkylammonium Salts of 6-Iodo-2-aminopurine to a Cyclobutyl Triflate: Efficient Preparation of Homochiral BMS-180,194, a Potent Antiviral Carbocyclic Nucleoside

Aminodiol HIV protease inhibitors. 1. Design, synthesis, and preliminary SAR

Discovery of ( R )-7-Cyano-2,3,4,5-tetrahydro-1-(1 H -imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1 H -1,4-benzodiazepine (BMS-214662), a Farnesyltransferase Inhibitor with Potent Preclinical Antitumor Activity

2023 ESC Guidelines for the management of acute coronary syndromes

Synthesis of cinchona alkaloids via quinuclidine precursors

Discovery and Structure−Activity Relationships of Imidazole-Containing Tetrahydrobenzodiazepine Inhibitors of Farnesyltransferase

A Practical Asymmetric Synthesis of the Antiviral Agent Lobucavir, BMS-180194

α-hydroxyamide derived aminodiols as potent inhibitors of hiv protease

Total synthesis of pseudomonic acid C

Synthesis of daunosamine

Total synthesis of Cinchona alkaloids. 4. Syntheses via quinuclidine precursors

Total synthesis of Cinchona alkaloids. 3. Syntheses of quinuclidine intermediates

Reinvestigation of the classical synthesis of Cinchona alkaloids. I. A new synthesis of homomeroquinene and quinotoxine

ChemInform Abstract: REINVESTIGATION OF THE CLASSICAL SYNTHESIS OF CINCHONA ALKALOIDS PART 1, A NEW SYNTHESIS OF HOMOMEXOQUINENE AND QUINOTOXINE

ChemInform Abstract: SYNTH. VON CINCHONA‐ALKALOIDEN UEBER CHINUCLIDIN‐VORLAEUFER

A Selective Sweep on a Deleterious Mutation in CPT1A in Arctic Populations

Evidence of Early-Stage Selection on EPAS1 and GPR126 Genes in Andean High Altitude Populations

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