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Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice

Cell host & microbe, 2016-02, Vol.19 (2), p.181-193

2016

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Sex-Based Differences in Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection

The Journal of immunology (1950), 2017-05, Vol.198 (10), p.4046-4053

2017

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Severe Acute Respiratory Syndrome Coronavirus 2–Induced Immune Activation and Death of Monocyte-Derived Human Macrophages and Dendritic Cells

The Journal of infectious diseases, 2021-03, Vol.223 (5), p.785-795

2021

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Airway Memory CD4+ T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses

Immunity (Cambridge, Mass.), 2016-06, Vol.44 (6), p.1379-1391

2016

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The TMPRSS2 Inhibitor Nafamostat Reduces SARS-CoV-2 Pulmonary Infection in Mouse Models of COVID-19

mBio, 2021-08, Vol.12 (4), p.e0097021-e0097021

2021

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COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice

Nature (London), 2021-01, Vol.589 (7843), p.603-607

2021

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Severe Acute Respiratory Syndrome Coronavirus Infection Causes Neuronal Death in the Absence of Encephalitis in Mice Transgenic for Human ACE2

Journal of Virology, 2008-08, Vol.82 (15), p.7264-7275

2008

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3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice

Science translational medicine, 2020-08, Vol.12 (557)

2020

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Critical role of phospholipase A2 group IID in age-related susceptibility to severe acute respiratory syndrome-CoV infection

The Journal of experimental medicine, 2015-10, Vol.212 (11), p.1851-1868

2015

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Rigid respiration: fulminant pulmonary fibrosis after COVID-19

EBioMedicine, 2023-01, Vol.87, p.104428-104428, Article 104428

Meyerholz, David K.

2023

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The TCF-1 and LEF-1 Transcription Factors Have Cooperative and Opposing Roles in T Cell Development and Malignancy

Immunity (Cambridge, Mass.), 2012-11, Vol.37 (5), p.813-826

2012

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Microglia depletion exacerbates demyelination and impairs remyelination in a neurotropic coronavirus infection

Proceedings of the National Academy of Sciences - PNAS, 2020-09, Vol.117 (39), p.24464-24474

2020

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The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection

mBio, 2016-12, Vol.7 (6)

2016

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Airway acidification initiates host defense abnormalities in cystic fibrosis mice

Science (American Association for the Advancement of Science), 2016-01, Vol.351 (6272), p.503-507

2016

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RSV vaccine-enhanced disease is orchestrated by the combined actions of distinct CD4 T cell subsets

PLoS pathogens, 2015-03, Vol.11 (3), p.e1004757-e1004757

2015

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Mouse-adapted MERS coronavirus causes lethal lung disease in human DPP4 knockin mice

Proceedings of the National Academy of Sciences - PNAS, 2017-04, Vol.114 (15), p.E3119-E3128

2017

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Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia

Nature communications, 2019-10, Vol.10 (1), p.4906-12, Article 4906

2019

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Memory CD8 T cells mediate severe immunopathology following respiratory syncytial virus infection

PLoS pathogens, 2018-01, Vol.14 (1), p.e1006810-e1006810

2018

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Gel-forming mucins form distinct morphologic structures in airways

Proceedings of the National Academy of Sciences - PNAS, 2017-06, Vol.114 (26), p.6842-6847

2017

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Loss of murine Paneth cell function alters the immature intestinal microbiome and mimics changes seen in neonatal necrotizing enterocolitis

PloS one, 2018-10, Vol.13 (10), p.e0204967

2018

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Angiotensin II-induced hypertension and cardiac hypertrophy are differentially mediated by TLR3- and TLR4-dependent pathways

American journal of physiology. Heart and circulatory physiology, 2019-05, Vol.316 (5), p.H1027-H1038

2019

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Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract

EBioMedicine, 2020-10, Vol.60, p.102976, Article 102976

2020

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CFTR-rich ionocytes mediate chloride absorption across airway epithelia

The Journal of clinical investigation, 2023-10, Vol.133 (20), p.1-11

2023

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Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors

Nature biotechnology, 2009-09, Vol.27 (9), p.839-846

2009

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Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice

Sex-Based Differences in Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection

Severe Acute Respiratory Syndrome Coronavirus 2–Induced Immune Activation and Death of Monocyte-Derived Human Macrophages and Dendritic Cells

Airway Memory CD4+ T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses

The TMPRSS2 Inhibitor Nafamostat Reduces SARS-CoV-2 Pulmonary Infection in Mouse Models of COVID-19

COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice

Severe Acute Respiratory Syndrome Coronavirus Infection Causes Neuronal Death in the Absence of Encephalitis in Mice Transgenic for Human ACE2

3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice

Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment

Critical role of phospholipase A2 group IID in age-related susceptibility to severe acute respiratory syndrome-CoV infection

Rigid respiration: fulminant pulmonary fibrosis after COVID-19

The TCF-1 and LEF-1 Transcription Factors Have Cooperative and Opposing Roles in T Cell Development and Malignancy

Microglia depletion exacerbates demyelination and impairs remyelination in a neurotropic coronavirus infection

The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection

Airway acidification initiates host defense abnormalities in cystic fibrosis mice

RSV vaccine-enhanced disease is orchestrated by the combined actions of distinct CD4 T cell subsets

Mouse-adapted MERS coronavirus causes lethal lung disease in human DPP4 knockin mice

Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia

Memory CD8 T cells mediate severe immunopathology following respiratory syncytial virus infection

Gel-forming mucins form distinct morphologic structures in airways

Loss of murine Paneth cell function alters the immature intestinal microbiome and mimics changes seen in neonatal necrotizing enterocolitis

Angiotensin II-induced hypertension and cardiac hypertrophy are differentially mediated by TLR3- and TLR4-dependent pathways

Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract

CFTR-rich ionocytes mediate chloride absorption across airway epithelia

Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors

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