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Identification of essential genes for cancer immunotherapy

Nature (London), 2017-08, Vol.548 (7669), p.537-542

2017

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AXL/AKT axis mediated-resistance to BRAF inhibitor depends on PTEN status in melanoma

Oncogene, 2018-06, Vol.37 (24), p.3275-3289

2018

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Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry

Cancer cell, 2014-06, Vol.25 (6), p.831-845

2014

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MicroRNA reexpression as differentiation therapy in cancer

The Journal of clinical investigation, 2009-08, Vol.119 (8), p.2119-2123

2009

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Naturally Occurring Canine Melanoma as a Predictive Comparative Oncology Model for Human Mucosal and Other Triple Wild-Type Melanomas

International journal of molecular sciences, 2018-01, Vol.19 (2), p.394

2018

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Ezrin mediates both HGF/Met autocrine and non‐autocrine signaling‐induced metastasis in melanoma

International journal of cancer, 2018-04, Vol.142 (8), p.1652-1663

2018

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CAR NK Cell Therapy for the Treatment of Metastatic Melanoma: Potential & Prospects

Cells (Basel, Switzerland), 2023-11, Vol.12 (23), p.2750

2023

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Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis

Nature communications, 2020-01, Vol.11 (1), p.333-18, Article 333

2020

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Using the single-cell imaging system and orthotropic footpad injection to establish mouse models for experimental and spontaneous melanoma metastasis

STAR protocols, 2023-09, Vol.4 (3), p.102349-102349, Article 102349

2023

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Development of Personalized Strategies for Precisely Battling Malignant Melanoma

International journal of molecular sciences, 2024-05, Vol.25 (9), p.5023

2024

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Integrated Genomics Identifies miR-32/MCL-1 Pathway as a Critical Driver of Melanomagenesis: Implications for miR-Replacement and Combination Therapy

PloS one, 2016-11, Vol.11 (11), p.e0165102-e0165102

2016

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Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response

Nature communications, 2023-05, Vol.14 (1), p.2744-2744, Article 2744

2023

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A direct link between MITF, innate immunity, and hair graying

PLoS biology, 2018-05, Vol.16 (5), p.e2003648-e2003648

2018

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A novel PD-L1-targeted shark VNAR single-domain-based CAR-T cell strategy for treating breast cancer and liver cancer

Molecular therapy. Oncolytics, 2022-03, Vol.24, p.849-863

2022

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Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma

PLoS genetics, 2015-01, Vol.11 (1), p.e1004877-e1004877

2015

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Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators

Nature medicine, 2004-02, Vol.10 (2), p.175-181

2004

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Ez-Metastasizing: The Crucial Roles of Ezrin in Metastasis

Cells (Basel, Switzerland), 2023-06, Vol.12 (12), p.1620

2023

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p53 Loss Increases the Osteogenic Differentiation of Bone Marrow Stromal Cells

Stem cells (Dayton, Ohio), 2015-04, Vol.33 (4), p.1304-1319

2015

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MiR-24 tumor suppressor activity is regulated independent of p53 and through a target site polymorphism

PloS one, 2009-12, Vol.4 (12), p.e8445

2009

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Protein arginine methyltransferase 5 regulates ERK1/2 signal transduction amplitude and cell fate through CRAF

Science signaling, 2011-09, Vol.4 (190), p.ra58

2011

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The homeoprotein Six1 transcriptionally activates multiple protumorigenic genes but requires ezrin to promote metastasis

Cancer research (Chicago, Ill.), 2006-02, Vol.66 (4), p.1982-1989

2006

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PERK mediates resistance to BRAF inhibition in melanoma with impaired PTEN

NPJ precision oncology, 2021-07, Vol.5 (1), p.68-68, Article 68

2021

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Synergistic targeted inhibition of MEK and dual PI3K/mTOR diminishes viability and inhibits tumor growth of canine melanoma underscoring its utility as a preclinical model for human mucosal melanoma

Pigment cell and melanoma research, 2016-11, Vol.29 (6), p.643-655

2016

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Hepatocyte growth factor/scatter factor activates proliferation in melanoma cells through p38 MAPK, ATF-2 and cyclin D1

Oncogene, 2002-02, Vol.21 (7), p.1000-1008

2002

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ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence

Proceedings of the National Academy of Sciences - PNAS, 2007-06, Vol.104 (26), p.10968-10973

2007

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Identification of essential genes for cancer immunotherapy

AXL/AKT axis mediated-resistance to BRAF inhibitor depends on PTEN status in melanoma

Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry

MicroRNA reexpression as differentiation therapy in cancer

Naturally Occurring Canine Melanoma as a Predictive Comparative Oncology Model for Human Mucosal and Other Triple Wild-Type Melanomas

Ezrin mediates both HGF/Met autocrine and non‐autocrine signaling‐induced metastasis in melanoma

CAR NK Cell Therapy for the Treatment of Metastatic Melanoma: Potential & Prospects

Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis

Using the single-cell imaging system and orthotropic footpad injection to establish mouse models for experimental and spontaneous melanoma metastasis

Development of Personalized Strategies for Precisely Battling Malignant Melanoma

Integrated Genomics Identifies miR-32/MCL-1 Pathway as a Critical Driver of Melanomagenesis: Implications for miR-Replacement and Combination Therapy

Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response

A direct link between MITF, innate immunity, and hair graying

A novel PD-L1-targeted shark VNAR single-domain-based CAR-T cell strategy for treating breast cancer and liver cancer

Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma

Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators

Ez-Metastasizing: The Crucial Roles of Ezrin in Metastasis

p53 Loss Increases the Osteogenic Differentiation of Bone Marrow Stromal Cells

MiR-24 tumor suppressor activity is regulated independent of p53 and through a target site polymorphism

Protein arginine methyltransferase 5 regulates ERK1/2 signal transduction amplitude and cell fate through CRAF

The homeoprotein Six1 transcriptionally activates multiple protumorigenic genes but requires ezrin to promote metastasis

PERK mediates resistance to BRAF inhibition in melanoma with impaired PTEN

Synergistic targeted inhibition of MEK and dual PI3K/mTOR diminishes viability and inhibits tumor growth of canine melanoma underscoring its utility as a preclinical model for human mucosal melanoma

Hepatocyte growth factor/scatter factor activates proliferation in melanoma cells through p38 MAPK, ATF-2 and cyclin D1

ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence

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