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Editorial: Molecular Mechanisms of Voltage-Gating in Ion Channels

Frontiers in pharmacology, 2021-09, Vol.12, p.768153-768153

2021

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Computer modeling of whole-cell voltage-clamp analyses to delineate guidelines for good practice of manual and automated patch-clamp

Scientific reports, 2021-02, Vol.11 (1), p.3282-3282, Article 3282

2021

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Structure of a Prokaryotic Sodium Channel Pore Reveals Essential Gating Elements and an Outer Ion Binding Site Common to Eukaryotic Channels

Journal of molecular biology, 2014-01, Vol.426 (2), p.467-483

2014

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Up-regulation of voltage-gated sodium channels by peptides mimicking S4-S5 linkers reveals a variation of the ligand-receptor mechanism

Scientific reports, 2020-04, Vol.10 (1), p.5852-5852, Article 5852

2020

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Disruption of a Conservative Motif in the C-Terminal Loop of the KCNQ1 Channel Causes LQT Syndrome

International journal of molecular sciences, 2022-07, Vol.23 (14), p.7953

2022

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hERG S4-S5 linker acts as a voltage-dependent ligand that binds to the activation gate and locks it in a closed state

Scientific reports, 2017-03, Vol.7 (1), p.113-113, Article 113

2017

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Delayed rectifier K+ currents and cardiac repolarization

Journal of molecular and cellular cardiology, 2010-01, Vol.48 (1), p.37-44

2010

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Functional Impact of BeKm-1, a High-Affinity hERG Blocker, on Cardiomyocytes Derived from Human-Induced Pluripotent Stem Cells

International journal of molecular sciences, 2020-10, Vol.21 (19), p.7167

2020

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A need for exhaustive and standardized characterization of ion channels activity. The case of KV11.1

Frontiers in physiology, 2023-02, Vol.14, p.1132533-1132533

2023

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Toward Personalized Medicine: Using Cardiomyocytes Differentiated From Urine-Derived Pluripotent Stem Cells to Recapitulate Electrophysiological Characteristics of Type 2 Long QT Syndrome

Journal of the American Heart Association, 2015-09, Vol.4 (9), p.e002159-e002159

2015

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A functional network of highly pure enteric neurons in a dish

Frontiers in neuroscience, 2023-01, Vol.16, p.1062253-1062253

2023

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Kv7.1 (KCNQ1) properties and channelopathies

The Journal of physiology, 2008-04, Vol.586 (7), p.1785-1789

2008

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HIV-Tat induces a decrease in I Kr and I Ks via reduction in phosphatidylinositol-(4,5)-bisphosphate availability

Journal of molecular and cellular cardiology, 2016-10, Vol.99, p.1-13

2016

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Dual Effect of Phosphatidyl (4,5)-Bisphosphate PIP2 on Shaker K+ Channels

The Journal of biological chemistry, 2012-10, Vol.287 (43), p.36158-36167

2012

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Marine n-3 PUFAs modulate IKs gating, channel expression, and location in membrane microdomains

Cardiovascular research, 2015-02, Vol.105 (2), p.223-232

2015

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Physiological and Pathophysiological Insights of Nav1.4 and Nav1.5 Comparison

Frontiers in pharmacology, 2016-01, Vol.6, p.314-314

2016

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SARS-CoV-2 E and 3a Proteins Are Inducers of Pannexin Currents

Cells (Basel, Switzerland), 2023-05, Vol.12 (11), p.1474

2023

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Polyethylenimine but Not Cationic Lipids Promotes Transgene Delivery to the Nucleus in Mammalian Cells

The Journal of biological chemistry, 1998-03, Vol.273 (13), p.7507-7511

1998

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Predicting hERG repolarization power at 37°C from recordings at room temperature

Clinical and translational medicine, 2023-05, Vol.13 (5), p.e1266-n/a

2023

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A long QT mutation substitutes cholesterol for phosphatidylinositol-4,5-bisphosphate in KCNQ1 channel regulation

PloS one, 2014-03, Vol.9 (3), p.e93255-e93255

2014

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A Novel Method for Measurement of Submembrane ATP Concentration

The Journal of biological chemistry, 2000-09, Vol.275 (39), p.30046-30049

2000

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Impaired KCNQ1–KCNE1 and Phosphatidylinositol-4,5-Bisphosphate Interaction Underlies the Long QT Syndrome

Circulation research, 2005-04, Vol.96 (7), p.730-739

2005

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A standardised hERG phenotyping pipeline to evaluate KCNH2 genetic variant pathogenicity

Clinical and translational medicine, 2021-11, Vol.11 (11), p.e609-n/a

2021

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Phosphatidylinositol-4,5-Bisphosphate (PIP2) Stabilizes the Open Pore Conformation of the Kv11.1 (hERG) Channel

Biophysical journal, 2010-08, Vol.99 (4), p.1110-1118

2010

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A consistent arrhythmogenic trait in Brugada syndrome cellular phenotype

Clinical and translational medicine, 2021-06, Vol.11 (6), p.e413-n/a

2021

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Editorial: Molecular Mechanisms of Voltage-Gating in Ion Channels

Computer modeling of whole-cell voltage-clamp analyses to delineate guidelines for good practice of manual and automated patch-clamp

Structure of a Prokaryotic Sodium Channel Pore Reveals Essential Gating Elements and an Outer Ion Binding Site Common to Eukaryotic Channels

Up-regulation of voltage-gated sodium channels by peptides mimicking S4-S5 linkers reveals a variation of the ligand-receptor mechanism

Disruption of a Conservative Motif in the C-Terminal Loop of the KCNQ1 Channel Causes LQT Syndrome

hERG S4-S5 linker acts as a voltage-dependent ligand that binds to the activation gate and locks it in a closed state

Delayed rectifier K+ currents and cardiac repolarization

Functional Impact of BeKm-1, a High-Affinity hERG Blocker, on Cardiomyocytes Derived from Human-Induced Pluripotent Stem Cells

A need for exhaustive and standardized characterization of ion channels activity. The case of KV11.1

Toward Personalized Medicine: Using Cardiomyocytes Differentiated From Urine-Derived Pluripotent Stem Cells to Recapitulate Electrophysiological Characteristics of Type 2 Long QT Syndrome

A functional network of highly pure enteric neurons in a dish

Kv7.1 (KCNQ1) properties and channelopathies

HIV-Tat induces a decrease in I Kr and I Ks via reduction in phosphatidylinositol-(4,5)-bisphosphate availability

Dual Effect of Phosphatidyl (4,5)-Bisphosphate PIP2 on Shaker K+ Channels

Marine n-3 PUFAs modulate IKs gating, channel expression, and location in membrane microdomains

Physiological and Pathophysiological Insights of Nav1.4 and Nav1.5 Comparison

SARS-CoV-2 E and 3a Proteins Are Inducers of Pannexin Currents

Polyethylenimine but Not Cationic Lipids Promotes Transgene Delivery to the Nucleus in Mammalian Cells

Predicting hERG repolarization power at 37°C from recordings at room temperature

A long QT mutation substitutes cholesterol for phosphatidylinositol-4,5-bisphosphate in KCNQ1 channel regulation

A Novel Method for Measurement of Submembrane ATP Concentration

Impaired KCNQ1–KCNE1 and Phosphatidylinositol-4,5-Bisphosphate Interaction Underlies the Long QT Syndrome

A standardised hERG phenotyping pipeline to evaluate KCNH2 genetic variant pathogenicity

Phosphatidylinositol-4,5-Bisphosphate (PIP2) Stabilizes the Open Pore Conformation of the Kv11.1 (hERG) Channel

A consistent arrhythmogenic trait in Brugada syndrome cellular phenotype

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