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Mechanistic insights on the mode of action of an antiproliferative thiosemicarbazone-nickel complex revealed by an integrated chemogenomic profiling study

Scientific reports, 2020-06, Vol.10 (1), p.10524-14, Article 10524

2020

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Weight Loss and Nutritional Aspects After Biliopancreatic Diversion and Its Variants

Obesity surgery, 2022-06, Vol.32 (6), p.2094-2095

2022

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A Yeast-Based Repurposing Approach for the Treatment of Mitochondrial DNA Depletion Syndromes Led to the Identification of Molecules Able to Modulate the dNTP Pool

International journal of molecular sciences, 2021-11, Vol.22 (22), p.12223

2021

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Yeast expression of mammalian Onzin and fungal FCR1 suggests ancestral functions of PLAC8 proteins in mitochondrial metabolism and DNA repair

Scientific reports, 2019-04, Vol.9 (1), p.6629, Article 6629

2019

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Biallelic mutations of the methionyl-tRNA synthetase (MARS) cause a specific type of pulmonary alveolar proteinosis prevalent on Réunion Island

American journal of human genetics, 2015-05, Vol.96 (5), p.826-831

2015

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A Yeast-Based Screening Unravels Potential Therapeutic Molecules for Mitochondrial Diseases Associated with Dominant ANT1 Mutations

International journal of molecular sciences, 2021-05, Vol.22 (9), p.4461

2021

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Defective mitochondrial rRNA methyltransferase MRM2 causes MELAS-like clinical syndrome

Human molecular genetics, 2017-11, Vol.26 (21), p.4257-4266

2017

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Efficient clofilium tosylate-mediated rescue of POLG-related disease phenotypes in zebrafish

Cell death & disease, 2021-01, Vol.12 (1), p.100-18, Article 100

2021

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Recurrent De Novo Dominant Mutations in SLC25A4 Cause Severe Early-Onset Mitochondrial Disease and Loss of Mitochondrial DNA Copy Number

American journal of human genetics, 2016-10, Vol.99 (4), p.860-876

2016

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Zebrafish polg2 knock-out recapitulates human POLG-disorders; implications for drug treatment

Cell death & disease, 2024-04, Vol.15 (4), p.281-281, Article 281

2024

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Sabotage at the Powerhouse? Unraveling the Molecular Target of 2-Isopropylbenzaldehyde Thiosemicarbazone, a Specific Inhibitor of Aflatoxin Biosynthesis and Sclerotia Development in Aspergillus flavus , Using Yeast as a Model System

Molecules (Basel, Switzerland), 2019-08, Vol.24 (16), p.2971

2019

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Overexpression of DNA polymerase zeta reduces the mitochondrial mutability caused by pathological mutations in DNA polymerase gamma in yeast

PloS one, 2012-03, Vol.7 (3), p.e34322-e34322

2012

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Insights into Physiological and Genetic Mupirocin Susceptibility in Bifidobacteria

Applied and Environmental Microbiology, 2011-05, Vol.77 (9), p.3141-3146

2011

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Secretion of Human Serum Albumin by Kluyveromyces lactis Overexpressing KlPDI1 and KlERO1

Applied and Environmental Microbiology, 2005-08, Vol.71 (8), p.4359-4363

2005

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Deletion of the Glucose-6-Phosphate Dehydrogenase Gene KlZWF1 Affects both Fermentative and Respiratory Metabolism in Kluyveromyces lactis

Eukaryotic Cell, 2007-01, Vol.6 (1), p.19-27

2007

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Drug repositioning as a therapeutic strategy for neurodegenerations associated with OPA1 mutations

Human molecular genetics, 2021-01, Vol.29 (22), p.3631-3645

2021

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Dominance of yeast aac2R96H and aac2R252G mutations, equivalent to pathological mutations in ant1, is due to gain of function

Biochemical and biophysical research communications, 2017-11, Vol.493 (2), p.909-913

2017

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Dominance of yeast aac2 R96H and aac2 R252G mutations, equivalent to pathological mutations in ant1, is due to gain of function

Biochemical and biophysical research communications, 2017-11, Vol.493 (2), p.909-913

2017

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Deciphering OPA1 mutations pathogenicity by combined analysis of human, mouse and yeast cell models

Biochimica et biophysica acta. Molecular basis of disease, 2018-10, Vol.1864 (10), p.3496-3514

2018

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Structural modification of cuminaldehyde thiosemicarbazone increases inhibition specificity toward aflatoxin biosynthesis and sclerotia development in Aspergillus flavus

Applied microbiology and biotechnology, 2017-09, Vol.101 (17), p.6683-6696

2017

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The Power of Yeast in Modelling Human Nuclear Mutations Associated with Mitochondrial Diseases

Genes, 2021-02, Vol.12 (2), p.300

2021

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A Yeast-Based Screening Unravels Potential Therapeutic Molecules for Mitochondrial Diseases Associated with Dominant ANT1 Mutations

International journal of molecular sciences, 2021-04, Vol.22

2021

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In vitro evaluation of the activity of thiosemicarbazone derivatives against mycotoxigenic fungi affecting cereals

International journal of food microbiology, 2015-05, Vol.200, p.104-111

2015

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A Yeast-Based Screening Unravels Potential Therapeutic Molecules for Mitochondrial Diseases Associated with Dominant ANT1 Mutations

International journal of molecular sciences, 2021, Vol.22 (9)

2021

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Construction and validation of a yeast model system for studying in vivo the susceptibility to nucleoside analogues of DNA polymerase gamma allelic variants

Mitochondrion, 2010-03, Vol.10 (2), p.183-187

2010

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Mechanistic insights on the mode of action of an antiproliferative thiosemicarbazone-nickel complex revealed by an integrated chemogenomic profiling study

Weight Loss and Nutritional Aspects After Biliopancreatic Diversion and Its Variants

A Yeast-Based Repurposing Approach for the Treatment of Mitochondrial DNA Depletion Syndromes Led to the Identification of Molecules Able to Modulate the dNTP Pool

Yeast expression of mammalian Onzin and fungal FCR1 suggests ancestral functions of PLAC8 proteins in mitochondrial metabolism and DNA repair

Biallelic mutations of the methionyl-tRNA synthetase (MARS) cause a specific type of pulmonary alveolar proteinosis prevalent on Réunion Island

A Yeast-Based Screening Unravels Potential Therapeutic Molecules for Mitochondrial Diseases Associated with Dominant ANT1 Mutations

Defective mitochondrial rRNA methyltransferase MRM2 causes MELAS-like clinical syndrome

Efficient clofilium tosylate-mediated rescue of POLG-related disease phenotypes in zebrafish

Recurrent De Novo Dominant Mutations in SLC25A4 Cause Severe Early-Onset Mitochondrial Disease and Loss of Mitochondrial DNA Copy Number

Zebrafish polg2 knock-out recapitulates human POLG-disorders; implications for drug treatment

Sabotage at the Powerhouse? Unraveling the Molecular Target of 2-Isopropylbenzaldehyde Thiosemicarbazone, a Specific Inhibitor of Aflatoxin Biosynthesis and Sclerotia Development in Aspergillus flavus , Using Yeast as a Model System

Overexpression of DNA polymerase zeta reduces the mitochondrial mutability caused by pathological mutations in DNA polymerase gamma in yeast

Insights into Physiological and Genetic Mupirocin Susceptibility in Bifidobacteria

Secretion of Human Serum Albumin by Kluyveromyces lactis Overexpressing KlPDI1 and KlERO1

Deletion of the Glucose-6-Phosphate Dehydrogenase Gene KlZWF1 Affects both Fermentative and Respiratory Metabolism in Kluyveromyces lactis

Drug repositioning as a therapeutic strategy for neurodegenerations associated with OPA1 mutations

Dominance of yeast aac2R96H and aac2R252G mutations, equivalent to pathological mutations in ant1, is due to gain of function

Dominance of yeast aac2 R96H and aac2 R252G mutations, equivalent to pathological mutations in ant1, is due to gain of function

Deciphering OPA1 mutations pathogenicity by combined analysis of human, mouse and yeast cell models

Structural modification of cuminaldehyde thiosemicarbazone increases inhibition specificity toward aflatoxin biosynthesis and sclerotia development in Aspergillus flavus

The Power of Yeast in Modelling Human Nuclear Mutations Associated with Mitochondrial Diseases

A Yeast-Based Screening Unravels Potential Therapeutic Molecules for Mitochondrial Diseases Associated with Dominant ANT1 Mutations

In vitro evaluation of the activity of thiosemicarbazone derivatives against mycotoxigenic fungi affecting cereals

A Yeast-Based Screening Unravels Potential Therapeutic Molecules for Mitochondrial Diseases Associated with Dominant ANT1 Mutations

Construction and validation of a yeast model system for studying in vivo the susceptibility to nucleoside analogues of DNA polymerase gamma allelic variants

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