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Potent and Selective 1,2,3-Trisubstituted Indole NPY Y-1 Antagonists

Journal of medicinal chemistry, 1997-11, Vol.40 (23), p.3712-3714

1997

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LY303870, a centrally active neurokinin-1 antagonist with a long duration of action

The Journal of pharmacology and experimental therapeutics, 1997-02, Vol.280 (2), p.774

1997

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Pharmacological characterization of LY303870: a novel, potent and selective nonpeptide substance P (neurokinin-1) receptor antagonist

The Journal of pharmacology and experimental therapeutics, 1995-11, Vol.275 (2), p.737

1995

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Acyl Sulfonamide Anti-Proliferatives: Benzene Substituent Structure−Activity Relationships for a Novel Class of Antitumor Agents

Journal of medicinal chemistry, 2004-10, Vol.47 (22), p.5367-5380

2004

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3-Aryl-1,2-diacetamidopropane Derivatives as Novel and Potent NK-1 Receptor Antagonists

Journal of medicinal chemistry, 1996-02, Vol.39 (3), p.736-748

1996

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Expedited discovery of second generation NK-1 antagonists: identification of a nonbasic aryloxy substituent

Bioorganic & medicinal chemistry letters, 2001-07, Vol.11 (13), p.1643-1646

2001

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The non-peptide NK-1 receptor antagonist LY303870 inhibits neurogenic dural inflammation in guinea pigs

Life sciences (1973), 1997-03, Vol.60 (18), p.1553-1561

1997

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Acyl sulfonamide anti-proliferatives. Part 2: Activity of heterocyclic sulfonamide derivatives

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (3), p.617-620

2005

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Practical and Enantiospecific Synthesis of LY303870, a Novel NK-1 Antagonist

Journal of organic chemistry, 1995-10, Vol.60 (21), p.7033-7036

1995

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Diphenylpyrazolidinone and benzodiazepine cholecystokinin antagonists: A case of convergent evolution in medicinal chemistry

Bioorganic & medicinal chemistry letters, 1993-05, Vol.3 (5), p.875-880

1993

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ChemInform Abstract: Practical and Enantiospecific Synthesis of LY303870, a Novel NK-1 Antagonist

ChemInform, 1996-03, Vol.27 (11), p.no-no

1996

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ChemInform Abstract: 3-Aryl-1,2-diacetamidopropane Derivatives as Novel and Potent NK-1 Receptor Antagonists

ChemInform, 1996-05, Vol.27 (21), p.no-no

1996

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Do carer’s levels of unmet needs change over time when caring for patients diagnosed with high-grade glioma and how are these needs correlated with distress?

Supportive care in cancer, 2018, Vol.26 (1), p.275-286

2018

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Bereavement outcomes of carers of patients with high grade glioma: Experiences of support before and after the death

Death studies, 2023, Vol.47 (10), p.1094-1103

2023

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Carer preparedness improved by providing a supportive educational intervention for carers of patients with high-grade glioma: RCT results

Journal of neuro-oncology, 2023-02, Vol.161 (3), p.501-513

2023

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Discovery of 1‑(3,3-Dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3‑d]pyrimidin-6-yl)phenyl)urea (LY3009120) as a Pan-RAF Inhibitor with Minimal Paradoxical Activation and Activity against BRAF or RAS Mutant Tumor Cells

Journal of medicinal chemistry, 2015-05, Vol.58 (10), p.4165-4179

2015

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'If we get too close to your bones they'll go brittle': women's initial fears about radiotherapy for early breast cancer

Psycho-oncology (Chichester, England), 2008-09, Vol.17 (9), p.877-884

2008

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SANCDB: a South African natural compound database

Journal of cheminformatics, 2015-06, Vol.7 (1), p.29-29, Article 29

2015

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Soil properties and productivity as affected by topsoil movement within an eroded landform

Soil & tillage research, 2009, Vol.102 (1), p.67-77

2009

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Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk

American journal of human genetics, 2020-11, Vol.107 (5), p.837-848

2020

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Selecting Color‐based Tracers and Classifying Sediment Sources in the Assessment of Sediment Dynamics Using Sediment Source Fingerprinting

Journal of environmental quality, 2015-09, Vol.44 (5), p.1605-1616

2015

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Randomized phase 2 study of carboplatin and bevacizumab in recurrent glioblastoma

Neuro-oncology (Charlottesville, Va.), 2015-11, Vol.17 (11), p.1504-1513

2015

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Synthesis of 2,3-dihydroxy-3-(N-substituted carbamoyl)propylphosphonic acid derivatives as hybrid DOXP-fosmidomycin analogues

Journal of molecular structure, 2022-05, Vol.1256, p.132453, Article 132453

2022

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Are videoconferenced consultations as effective as face-to-face consultations for hereditary breast and ovarian cancer genetic counseling?

Genetics in medicine, 2011-11, Vol.13 (11), p.933-941

2011

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Exploring DOXP-reductoisomerase binding limits using phosphonated N-aryl and N-heteroarylcarboxamides as DXR inhibitors

Bioorganic & medicinal chemistry, 2013-07, Vol.21 (14), p.4332-4341

2013

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Potent and Selective 1,2,3-Trisubstituted Indole NPY Y-1 Antagonists

LY303870, a centrally active neurokinin-1 antagonist with a long duration of action

Pharmacological characterization of LY303870: a novel, potent and selective nonpeptide substance P (neurokinin-1) receptor antagonist

Acyl Sulfonamide Anti-Proliferatives: Benzene Substituent Structure−Activity Relationships for a Novel Class of Antitumor Agents

3-Aryl-1,2-diacetamidopropane Derivatives as Novel and Potent NK-1 Receptor Antagonists

Expedited discovery of second generation NK-1 antagonists: identification of a nonbasic aryloxy substituent

The non-peptide NK-1 receptor antagonist LY303870 inhibits neurogenic dural inflammation in guinea pigs

Acyl sulfonamide anti-proliferatives. Part 2: Activity of heterocyclic sulfonamide derivatives

Practical and Enantiospecific Synthesis of LY303870, a Novel NK-1 Antagonist

Diphenylpyrazolidinone and benzodiazepine cholecystokinin antagonists: A case of convergent evolution in medicinal chemistry

ChemInform Abstract: Practical and Enantiospecific Synthesis of LY303870, a Novel NK-1 Antagonist

ChemInform Abstract: 3-Aryl-1,2-diacetamidopropane Derivatives as Novel and Potent NK-1 Receptor Antagonists

Do carer’s levels of unmet needs change over time when caring for patients diagnosed with high-grade glioma and how are these needs correlated with distress?

Bereavement outcomes of carers of patients with high grade glioma: Experiences of support before and after the death

Carer preparedness improved by providing a supportive educational intervention for carers of patients with high-grade glioma: RCT results

Discovery of 1‑(3,3-Dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3‑d]pyrimidin-6-yl)phenyl)urea (LY3009120) as a Pan-RAF Inhibitor with Minimal Paradoxical Activation and Activity against BRAF or RAS Mutant Tumor Cells

'If we get too close to your bones they'll go brittle': women's initial fears about radiotherapy for early breast cancer

SANCDB: a South African natural compound database

Soil properties and productivity as affected by topsoil movement within an eroded landform

Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk

Selecting Color‐based Tracers and Classifying Sediment Sources in the Assessment of Sediment Dynamics Using Sediment Source Fingerprinting

Randomized phase 2 study of carboplatin and bevacizumab in recurrent glioblastoma

Synthesis of 2,3-dihydroxy-3-(N-substituted carbamoyl)propylphosphonic acid derivatives as hybrid DOXP-fosmidomycin analogues

Are videoconferenced consultations as effective as face-to-face consultations for hereditary breast and ovarian cancer genetic counseling?

Exploring DOXP-reductoisomerase binding limits using phosphonated N-aryl and N-heteroarylcarboxamides as DXR inhibitors

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