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Review: Metabolic Regulation of Inflammation in Osteoarthritis

Arthritis & rheumatology (Hoboken, N.J.), 2017-01, Vol.69 (1), p.9-21

2017

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Targeting CD38 to Suppress Osteoarthritis Development and Associated Pain After Joint Injury in Mice

Arthritis & rheumatology (Hoboken, N.J.), 2023-03, Vol.75 (3), p.364-374

2023

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Emerging regulators of the inflammatory process in osteoarthritis

Nature reviews. Rheumatology, 2015-01, Vol.11 (1), p.35

2015

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Emerging role of metabolic signaling in synovial joint remodeling and osteoarthritis

Journal of orthopaedic research, 2016-12, Vol.34 (12), p.2048-2058

2016

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Impaired Proteasomal Function in Human Osteoarthritic Chondrocytes Can Contribute to Decreased Levels of SOX9 and Aggrecan

Arthritis & rheumatology (Hoboken, N.J.), 2018-07, Vol.70 (7), p.1030-1041

2018

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Differential DNA Methylation of Networked Signaling, Transcriptional, Innate and Adaptive Immunity, and Osteoclastogenesis Genes and Pathways in Gout

Arthritis & rheumatology (Hoboken, N.J.), 2020-05, Vol.72 (5), p.802-814

2020

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Amplification of Inflammation by Lubricin Deficiency Implicated in Incident, Erosive Gout Independent of Hyperuricemia

Arthritis & rheumatology (Hoboken, N.J.), 2023-05, Vol.75 (5), p.794-805

2023

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A vascular smooth muscle cell X-box binding protein 1 and transglutaminase 2 regulatory circuit limits neointimal hyperplasia

PloS one, 2019-04, Vol.14 (4), p.e0212235-e0212235

2019

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Mitochondrial Biogenesis Is Impaired in Osteoarthritis Chondrocytes but Reversible via Peroxisome Proliferator–Activated Receptor γ Coactivator 1α

Arthritis & rheumatology (Hoboken, N.J.), 2015-05, Vol.67 (8), p.2141-2153

2015

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Cartilage‐targeting ultrasmall lipid‐polymer hybrid nanoparticles for the prevention of cartilage degradation

Bioengineering & translational medicine, 2021-01, Vol.6 (1), p.e10187-n/a

2021

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Peroxisome Proliferator–Activated Receptor γ Coactivator 1α and FoxO3A Mediate Chondroprotection by AMP‐Activated Protein Kinase

Arthritis & rheumatology (Hoboken, N.J.), 2014-11, Vol.66 (11), p.3073-3082

2014

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AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages

Annals of the rheumatic diseases, 2016-01, Vol.75 (1), p.286-294

2016

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AMPK Activation by A-769662 Controls IL-6 Expression in Inflammatory Arthritis

PloS one, 2015-10, Vol.10 (10), p.e0140452

2015

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Intracellular innate immunity in gouty arthritis: role of NALP3 inflammasome

Immunology and cell biology, 2010-01, Vol.88 (1), p.20-23

Liu‐Bryan, Ru

2010

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A Subpopulation of Macrophages Infiltrates Hypertrophic Adipose Tissue and Is Activated by Free Fatty Acids via Toll-like Receptors 2 and 4 and JNK-dependent Pathways

The Journal of biological chemistry, 2007-11, Vol.282 (48), p.35279-35292

2007

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Modulation of matrix metabolism by ATP-citrate lyase in articular chondrocytes

The Journal of biological chemistry, 2018-08, Vol.293 (31), p.12259-12270

2018

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Linked decreases in liver kinase B1 and AMP-activated protein kinase activity modulate matrix catabolic responses to biomechanical injury in chondrocytes

Arthritis research & therapy, 2013-07, Vol.15 (4), p.R77-R77

2013

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Protocol for preparing monosodium urate crystals for in vitro and in vivo studies in mouse and human cells

STAR protocols, 2024-06, Vol.5 (2), p.103030, Article 103030

2024

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Monosodium urate crystals regulate a unique JNK-dependent macrophage metabolic and inflammatory response

Cell reports (Cambridge), 2022-03, Vol.38 (10), p.110489-110489, Article 110489

2022

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Xanthine oxidase inhibitor urate-lowering therapy titration to target decreases serum free fatty acids in gout and suppresses lipolysis by adipocytes

Arthritis research & therapy, 2022-07, Vol.24 (1), p.175-13, Article 175

2022

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Arhalofenate acid inhibits monosodium urate crystal-induced inflammatory responses through activation of AMP-activated protein kinase (AMPK) signaling

Arthritis research & therapy, 2018-09, Vol.20 (1), p.204-204, Article 204

2018

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Engagement of CD14 Mediates the Inflammatory Potential of Monosodium Urate Crystals

Journal of Immunology, 2006-11, Vol.177 (9), p.6370-6378

2006

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TLR2 Signaling in Chondrocytes Drives Calcium Pyrophosphate Dihydrate and Monosodium Urate Crystal-Induced Nitric Oxide Generation

The Journal of immunology (1950), 2005-04, Vol.174 (8), p.5016-5023

2005

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Targeting phosphatase-dependent proteoglycan switch for rheumatoid arthritis therapy

Science translational medicine, 2015-05, Vol.7 (288), p.288ra76

2015

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RAGE signaling mediates post-injury arterial neointima formation by suppression of liver kinase B1 and AMPK activity

Atherosclerosis, 2012-06, Vol.222 (2), p.417-425

2012

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Review: Metabolic Regulation of Inflammation in Osteoarthritis

Targeting CD38 to Suppress Osteoarthritis Development and Associated Pain After Joint Injury in Mice

Emerging regulators of the inflammatory process in osteoarthritis

Emerging role of metabolic signaling in synovial joint remodeling and osteoarthritis

Impaired Proteasomal Function in Human Osteoarthritic Chondrocytes Can Contribute to Decreased Levels of SOX9 and Aggrecan

Differential DNA Methylation of Networked Signaling, Transcriptional, Innate and Adaptive Immunity, and Osteoclastogenesis Genes and Pathways in Gout

Amplification of Inflammation by Lubricin Deficiency Implicated in Incident, Erosive Gout Independent of Hyperuricemia

A vascular smooth muscle cell X-box binding protein 1 and transglutaminase 2 regulatory circuit limits neointimal hyperplasia

Mitochondrial Biogenesis Is Impaired in Osteoarthritis Chondrocytes but Reversible via Peroxisome Proliferator–Activated Receptor γ Coactivator 1α

Cartilage‐targeting ultrasmall lipid‐polymer hybrid nanoparticles for the prevention of cartilage degradation

Peroxisome Proliferator–Activated Receptor γ Coactivator 1α and FoxO3A Mediate Chondroprotection by AMP‐Activated Protein Kinase

AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages

AMPK Activation by A-769662 Controls IL-6 Expression in Inflammatory Arthritis

Intracellular innate immunity in gouty arthritis: role of NALP3 inflammasome

A Subpopulation of Macrophages Infiltrates Hypertrophic Adipose Tissue and Is Activated by Free Fatty Acids via Toll-like Receptors 2 and 4 and JNK-dependent Pathways

Modulation of matrix metabolism by ATP-citrate lyase in articular chondrocytes

Linked decreases in liver kinase B1 and AMP-activated protein kinase activity modulate matrix catabolic responses to biomechanical injury in chondrocytes

Protocol for preparing monosodium urate crystals for in vitro and in vivo studies in mouse and human cells

Monosodium urate crystals regulate a unique JNK-dependent macrophage metabolic and inflammatory response

Xanthine oxidase inhibitor urate-lowering therapy titration to target decreases serum free fatty acids in gout and suppresses lipolysis by adipocytes

Arhalofenate acid inhibits monosodium urate crystal-induced inflammatory responses through activation of AMP-activated protein kinase (AMPK) signaling

Engagement of CD14 Mediates the Inflammatory Potential of Monosodium Urate Crystals

TLR2 Signaling in Chondrocytes Drives Calcium Pyrophosphate Dihydrate and Monosodium Urate Crystal-Induced Nitric Oxide Generation

Targeting phosphatase-dependent proteoglycan switch for rheumatoid arthritis therapy

RAGE signaling mediates post-injury arterial neointima formation by suppression of liver kinase B1 and AMPK activity

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