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Aberrant Protein S-Nitrosylation in Neurodegenerative Diseases

Neuron (Cambridge, Mass.), 2013-05, Vol.78 (4), p.596-614

2013

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Nitric Oxide-Dependent Protein Post-Translational Modifications Impair Mitochondrial Function and Metabolism to Contribute to Neurodegenerative Diseases

Antioxidants & redox signaling, 2020-04, Vol.32 (12), p.817-833

2020

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Direct Reprogramming of Adult Human Fibroblasts to Functional Neurons under Defined Conditions

Cell stem cell, 2011-08, Vol.9 (2), p.113-118

2011

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Pathologically activated therapeutics for neuroprotection

Nature reviews. Neuroscience, 2007-10, Vol.8 (10), p.803-808

Lipton, Stuart A

2007

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Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs

Free radical biology & medicine, 2013-12, Vol.65, p.645-657

2013

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Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond

Nature reviews. Drug discovery, 2006-02, Vol.5 (2), p.160-170

Lipton, Stuart A

2006

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‘SNO’-Storms Compromise Protein Activity and Mitochondrial Metabolism in Neurodegenerative Disorders

Trends in endocrinology and metabolism, 2017-12, Vol.28 (12), p.879-892

2017

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Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation

Immunity (Cambridge, Mass.), 2021-07, Vol.54 (7), p.1463-1477.e11

2021

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Mechanisms of glutamate toxicity in multiple sclerosis: biomarker and therapeutic opportunities

Lancet neurology, 2016-09, Vol.15 (10), p.1089-1102

2016

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Mitochondrial dynamics in cell death and neurodegeneration

Cellular and molecular life sciences : CMLS, 2010-10, Vol.67 (20), p.3435-3447

2010

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Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs isogenic controls

eLife, 2019-11, Vol.8

2019

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Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein

Nature communications, 2018-02, Vol.9 (1), p.817-17, Article 817

2018

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Direct reprogramming of mouse fibroblasts to neural progenitors

Proceedings of the National Academy of Sciences - PNAS, 2011-05, Vol.108 (19), p.7838-7843

2011

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Memantine preferentially blocks extrasynaptic over synaptic NMDA receptor currents in hippocampal autapses

The Journal of neuroscience, 2010-08, Vol.30 (33), p.11246-11250

2010

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Emerging hiPSC Models for Drug Discovery in Neurodegenerative Diseases

International journal of molecular sciences, 2021-07, Vol.22 (15), p.8196

2021

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Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors

Proceedings of the National Academy of Sciences - PNAS, 2011-05, Vol.108 (20), p.8299-8304

2011

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Aberrant protein S -nitrosylation contributes to the pathophysiology of neurodegenerative diseases

Neurobiology of disease, 2015-12, Vol.84, p.99-108

2015

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Potential Therapeutic Use of the Rosemary Diterpene Carnosic Acid for Alzheimer's Disease, Parkinson's Disease, and Long-COVID through NRF2 Activation to Counteract the NLRP3 Inflammasome

Antioxidants, 2022-01, Vol.11 (1), p.124

2022

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Cell death: protein misfolding and neurodegenerative diseases

Apoptosis (London), 2009-04, Vol.14 (4), p.455-468

2009

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NitroSynapsin ameliorates hypersynchronous neural network activity in Alzheimer hiPSC models

Molecular psychiatry, 2021-10, Vol.26 (10), p.5751-5765

2021

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Hydrogen Sulfide—Mechanisms of Toxicity and Development of an Antidote

Scientific reports, 2016-02, Vol.6 (1), p.20831, Article 20831

2016

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The chemical biology of clinically tolerated NMDA receptor antagonists

Journal of neurochemistry, 2006-06, Vol.97 (6), p.1611-1626

2006

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Noncanonical transnitrosylation network contributes to synapse loss in Alzheimer's disease

Science (American Association for the Advancement of Science), 2021-01, Vol.371 (6526)

2021

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Redox regulation of protein misfolding, mitochondrial dysfunction, synaptic damage, and cell death in neurodegenerative diseases

Experimental neurology, 2012-11, Vol.238 (1), p.12-21

2012

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Aberrant Protein S-Nitrosylation in Neurodegenerative Diseases

Nitric Oxide-Dependent Protein Post-Translational Modifications Impair Mitochondrial Function and Metabolism to Contribute to Neurodegenerative Diseases

Direct Reprogramming of Adult Human Fibroblasts to Functional Neurons under Defined Conditions

Pathologically activated therapeutics for neuroprotection

Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs

Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond

‘SNO’-Storms Compromise Protein Activity and Mitochondrial Metabolism in Neurodegenerative Disorders

Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation

Isogenic Human iPSC Parkinson’s Model Shows Nitrosative Stress-Induced Dysfunction in MEF2-PGC1α Transcription

Mechanisms of glutamate toxicity in multiple sclerosis: biomarker and therapeutic opportunities

Mitochondrial dynamics in cell death and neurodegeneration

Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs isogenic controls

Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein

Direct reprogramming of mouse fibroblasts to neural progenitors

Memantine preferentially blocks extrasynaptic over synaptic NMDA receptor currents in hippocampal autapses

Emerging hiPSC Models for Drug Discovery in Neurodegenerative Diseases

Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors

Aberrant protein S -nitrosylation contributes to the pathophysiology of neurodegenerative diseases

Potential Therapeutic Use of the Rosemary Diterpene Carnosic Acid for Alzheimer's Disease, Parkinson's Disease, and Long-COVID through NRF2 Activation to Counteract the NLRP3 Inflammasome

Cell death: protein misfolding and neurodegenerative diseases

NitroSynapsin ameliorates hypersynchronous neural network activity in Alzheimer hiPSC models

Hydrogen Sulfide—Mechanisms of Toxicity and Development of an Antidote

The chemical biology of clinically tolerated NMDA receptor antagonists

Noncanonical transnitrosylation network contributes to synapse loss in Alzheimer's disease

Redox regulation of protein misfolding, mitochondrial dysfunction, synaptic damage, and cell death in neurodegenerative diseases

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