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Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability

Molecular cell, 2016-07, Vol.63 (2), p.337-346

2016

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How does a protein's structure spell the difference between health and disease? Our journey to understand glaucoma-associated myocilin

PLoS biology, 2019-04, Vol.17 (4), p.e3000237-e3000237

Lieberman, Raquel L

2019

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Molecular Insights into Myocilin and Its Glaucoma-Causing Misfolded Olfactomedin Domain Variants

Accounts of chemical research, 2021-05, Vol.54 (9), p.2205-2215

2021

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Atomic Structure of a Fluorescent Ag8 Cluster Templated by a Multistranded DNA Scaffold

Journal of the American Chemical Society, 2019-07, Vol.141 (29), p.11465-11470

2019

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Progranulin deficiency leads to reduced glucocerebrosidase activity

PloS one, 2019-07, Vol.14 (7), p.e0212382-e0212382

2019

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Atomic Structure of a Fluorescent Ag 8 Cluster Templated by a Multistranded DNA Scaffold

Journal of the American Chemical Society, 2019-07, Vol.141 (29), p.11465-11470

2019

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Structure and stability of an apo thermophilic esterase that hydrolyzes polyhydroxybutyrate

Acta crystallographica. Section D, Structural biology, 2024-11, Vol.80 (11)

2024

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Lipid environment modulates processivity and kinetics of a presenilin homolog acting on multiple substrates in vitro

The Journal of biological chemistry, 2023-12, Vol.299 (12), p.105401, Article 105401

2023

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Correlation between chemical denaturation and the unfolding energetics of Acanthamoeba actophorin

Biophysical journal, 2023-07, Vol.122 (14), p.2921-2937

2023

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Discovery of Molecular Therapeutics for Glaucoma: Challenges, Successes, and Promising Directions

Journal of medicinal chemistry, 2016-02, Vol.59 (3), p.788-809

2016

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Myocilin misfolding and glaucoma: A 20-year update

Progress in retinal and eye research, 2023-07, Vol.95, p.101188-101188, Article 101188

2023

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Archaeal roots of intramembrane aspartyl protease siblings signal peptide peptidase and presenilin

Proteins, structure, function, and bioinformatics, 2021-02, Vol.89 (2), p.232-241

2021

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Structure and activity of a thermally stable mutant of Acanthamoeba actophorin

Acta crystallographica. Section F, Structural biology communications, 2022-04, Vol.78 (4), p.150-160

2022

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Mapping H+ in the Nanoscale (A2C4)2‑Ag8 Fluorophore

The journal of physical chemistry letters, 2022-12, Vol.13 (48), p.11317-11322

2022

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Mapping H + in the Nanoscale (A 2 C 4 ) 2 -Ag 8 Fluorophore

The journal of physical chemistry letters, 2022-12, Vol.13 (48), p.11317-11322

2022

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Improved resolution crystal structure of Acanthamoeba actophorin reveals structural plasticity not induced by microgravity

Acta crystallographica. Section F, Structural biology communications, 2021-12, Vol.77 (12), p.452-458

2021

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Biophysical characterization of the olfactomedin domain of myocilin, an extracellular matrix protein implicated in inherited forms of glaucoma

PloS one, 2011-01, Vol.6 (1), p.e16347-e16347

2011

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Change in Morphology of Dimyristoylphosphatidylcholine/Bile Salt Derivative Bicelle Assemblies with Dodecylmaltoside in the Disk and Ribbon Phases

The journal of physical chemistry letters, 2022-10, Vol.13 (42), p.9834-9840

2022

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Catalytically active holo Homo sapiens adenosine deaminase I adopts a closed conformation

Acta crystallographica. Section D, Biological crystallography., 2022-01, Vol.78 (1), p.91-103

2022

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Bioplastic degradation by a polyhydroxybutyrate depolymerase from a thermophilic soil bacterium

Protein science, 2022-11, Vol.31 (11), p.e4470-n/a

2022

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Common and rare myocilin variants: Predicting glaucoma pathogenicity based on genetics, clinical, and laboratory misfolding data

Human mutation, 2021-08, Vol.42 (8), p.903-946

2021

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Crystal structure of a membrane-bound metalloenzyme that catalyses the biological oxidation of methane

Nature, 2005-03, Vol.434 (7030), p.177-182

2005

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Calcium‐ligand variants of the myocilin olfactomedin propeller selected from invertebrate phyla reveal cross‐talk with N‐terminal blade and surface helices

Acta crystallographica. Section D, Biological crystallography., 2019-09, Vol.75 (9), p.817-824

2019

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Direct RT-qPCR detection of SARS-CoV-2 RNA from patient nasopharyngeal swabs without an RNA extraction step

PLoS biology, 2020-10, Vol.18 (10), p.e3000896-e3000896

2020

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Competition between inside-out unfolding and pathogenic aggregation in an amyloid-forming β-propeller

Nature communications, 2024-01, Vol.15 (1), p.155-155, Article 155

2024

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Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability

How does a protein's structure spell the difference between health and disease? Our journey to understand glaucoma-associated myocilin

Molecular Insights into Myocilin and Its Glaucoma-Causing Misfolded Olfactomedin Domain Variants

Atomic Structure of a Fluorescent Ag8 Cluster Templated by a Multistranded DNA Scaffold

Progranulin deficiency leads to reduced glucocerebrosidase activity

Atomic Structure of a Fluorescent Ag 8 Cluster Templated by a Multistranded DNA Scaffold

Structure and stability of an apo thermophilic esterase that hydrolyzes polyhydroxybutyrate

Lipid environment modulates processivity and kinetics of a presenilin homolog acting on multiple substrates in vitro

Correlation between chemical denaturation and the unfolding energetics of Acanthamoeba actophorin

Discovery of Molecular Therapeutics for Glaucoma: Challenges, Successes, and Promising Directions

Myocilin misfolding and glaucoma: A 20-year update

Archaeal roots of intramembrane aspartyl protease siblings signal peptide peptidase and presenilin

Structure and activity of a thermally stable mutant of Acanthamoeba actophorin

Mapping H+ in the Nanoscale (A2C4)2‑Ag8 Fluorophore

Mapping H + in the Nanoscale (A 2 C 4 ) 2 -Ag 8 Fluorophore

Improved resolution crystal structure of Acanthamoeba actophorin reveals structural plasticity not induced by microgravity

Biophysical characterization of the olfactomedin domain of myocilin, an extracellular matrix protein implicated in inherited forms of glaucoma

Change in Morphology of Dimyristoylphosphatidylcholine/Bile Salt Derivative Bicelle Assemblies with Dodecylmaltoside in the Disk and Ribbon Phases

Catalytically active holo Homo sapiens adenosine deaminase I adopts a closed conformation

Bioplastic degradation by a polyhydroxybutyrate depolymerase from a thermophilic soil bacterium

Common and rare myocilin variants: Predicting glaucoma pathogenicity based on genetics, clinical, and laboratory misfolding data

Crystal structure of a membrane-bound metalloenzyme that catalyses the biological oxidation of methane

Calcium‐ligand variants of the myocilin olfactomedin propeller selected from invertebrate phyla reveal cross‐talk with N‐terminal blade and surface helices

Direct RT-qPCR detection of SARS-CoV-2 RNA from patient nasopharyngeal swabs without an RNA extraction step

Competition between inside-out unfolding and pathogenic aggregation in an amyloid-forming β-propeller

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