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Kinase Inhibitor Drugs

1. Aufl., 2009

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Kinase and Histone Deacetylase Hybrid Inhibitors for Cancer Therapy

Journal of medicinal chemistry, 2019-04, Vol.62 (7), p.3171-3183

2019

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Inhibition of the Insulin-like Growth Factor-1 Receptor (IGF1R) Tyrosine Kinase as a Novel Cancer Therapy Approach

Journal of medicinal chemistry, 2009-08, Vol.52 (16), p.4981-5004

2009

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Drug Design Targeting the CXCR4/CXCR7/CXCL12 Pathway

Current topics in medicinal chemistry, 2016-05, Vol.16 (13), p.1441-1451

2016

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Design, Synthesis, Cytoselective Toxicity, Structure–Activity Relationships, and Pharmacophore of Thiazolidinone Derivatives Targeting Drug-Resistant Lung Cancer Cells

Journal of medicinal chemistry, 2008-03, Vol.51 (5), p.1242-1251

2008

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Marinopyrroles: Unique Drug Discoveries Based on Marine Natural Products

Medicinal research reviews, 2016-01, Vol.36 (1), p.169-189

Li, Rongshi

2016

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Assessment of Tissue Distribution and Metabolism of MP1, a Novel Pyrrolomycin, in Mice Using a Validated LC-MS/MS Method

Molecules (Basel, Switzerland), 2020-12, Vol.25 (24), p.5898

2020

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Marinopyrrole derivative MP1 as a novel anti-cancer agent in group 3 MYC-amplified Medulloblastoma

Journal of experimental & clinical cancer research, 2024-01, Vol.43 (1), p.18-18, Article 18

2024

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Natural Product-Based Drug Discovery

Medicinal research reviews, 2016-01, Vol.36 (1), p.3-3

Li, Rongshi

2016

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Effects of novel pyrrolomycin MP1 in MYCN amplified chemoresistant neuroblastoma cell lines alone and combined with temsirolimus

BMC cancer, 2019-08, Vol.19 (1), p.837-15, Article 837

2019

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Marinopyrrole derivatives as potential antibiotic agents against methicillin-resistant Staphylococcus aureus (II)

Marine drugs, 2013-08, Vol.11 (8), p.2927-2948

2013

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Fragment-Based and Structure-Guided Discovery and Optimization of Rho Kinase Inhibitors

Journal of medicinal chemistry, 2012-03, Vol.55 (5), p.2474-2478

2012

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Rho Kinase (ROCK) Inhibitors and Their Therapeutic Potential

Journal of medicinal chemistry, 2016-03, Vol.59 (6), p.2269-2300

2016

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Marinopyrrole derivatives as potential antibiotic agents against methicillin-resistant Staphylococcus aureus (III)

Marine drugs, 2014-04, Vol.12 (5), p.2458-2470

2014

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Remote Stereocontrolled Construction of Vicinal Axially Chiral Tetrasubstituted Allenes and Heteroatom-Functionalized Quaternary Carbon Stereocenters

Organic letters, 2019-01, Vol.21 (2), p.503-507

2019

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Design and Synthesis of Human Immunodeficiency Virus Entry Inhibitors: Sulfonamide as an Isostere for the α-Ketoamide Group

Journal of medicinal chemistry, 2007-12, Vol.50 (26), p.6535-6544

2007

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Cyclic Marinopyrrole Derivatives as Disruptors of Mcl-1 and Bcl-xL Binding to Bim

Marine drugs, 2014-03, Vol.12 (3), p.1335-1348

2014

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Fragment-based and natural product-derived antibiotics against ESKAPE pathogens

Journal of antivirals & antiretrovirals, 2018, Vol.10

Li, Rongshi

2018

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Enamine Catalytic Annulation of Azonaphthalenes: An Access to Indole Derivatives

Organic letters, 2019-08, Vol.21 (16), p.6557-6561

2019

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Drugs for the Treatment of Zika Virus Infection

Journal of medicinal chemistry, 2020-01, Vol.63 (2), p.470-489

2020

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Marinopyrrole derivatives with sulfide spacers as selective disruptors of Mcl-1 binding to pro-apoptotic protein Bim

Marine drugs, 2014-07, Vol.12 (8), p.4311-4325

2014

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Marinopyrrole derivatives as potential antibiotic agents against methicillin-resistant Staphylococcus aureus (I)

Marine drugs, 2012-04, Vol.10 (4), p.953-962

2012

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Design and Synthesis of 5-Aryl-pyridone-carboxamides as Inhibitors of Anaplastic Lymphoma Kinase

Journal of medicinal chemistry, 2006-02, Vol.49 (3), p.1006-1015

2006

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Marine natural products based drug discoveries

Journal of Pharmacognosy & Natural Products, 2016, Vol.2 (3)

Li, Rongshi

2016

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In Vitro Antimalarial Activity of Chalcones and Their Derivatives

Journal of medicinal chemistry, 1995-12, Vol.38 (26), p.5031-5037

1995

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Kinase Inhibitor Drugs

Kinase and Histone Deacetylase Hybrid Inhibitors for Cancer Therapy

Inhibition of the Insulin-like Growth Factor-1 Receptor (IGF1R) Tyrosine Kinase as a Novel Cancer Therapy Approach

Drug Design Targeting the CXCR4/CXCR7/CXCL12 Pathway

Design, Synthesis, Cytoselective Toxicity, Structure–Activity Relationships, and Pharmacophore of Thiazolidinone Derivatives Targeting Drug-Resistant Lung Cancer Cells

Marinopyrroles: Unique Drug Discoveries Based on Marine Natural Products

Assessment of Tissue Distribution and Metabolism of MP1, a Novel Pyrrolomycin, in Mice Using a Validated LC-MS/MS Method

Marinopyrrole derivative MP1 as a novel anti-cancer agent in group 3 MYC-amplified Medulloblastoma

Natural Product-Based Drug Discovery

Effects of novel pyrrolomycin MP1 in MYCN amplified chemoresistant neuroblastoma cell lines alone and combined with temsirolimus

Marinopyrrole derivatives as potential antibiotic agents against methicillin-resistant Staphylococcus aureus (II)

Fragment-Based and Structure-Guided Discovery and Optimization of Rho Kinase Inhibitors

Rho Kinase (ROCK) Inhibitors and Their Therapeutic Potential

Marinopyrrole derivatives as potential antibiotic agents against methicillin-resistant Staphylococcus aureus (III)

Remote Stereocontrolled Construction of Vicinal Axially Chiral Tetrasubstituted Allenes and Heteroatom-Functionalized Quaternary Carbon Stereocenters

Design and Synthesis of Human Immunodeficiency Virus Entry Inhibitors: Sulfonamide as an Isostere for the α-Ketoamide Group

Cyclic Marinopyrrole Derivatives as Disruptors of Mcl-1 and Bcl-xL Binding to Bim

Fragment-based and natural product-derived antibiotics against ESKAPE pathogens

Enamine Catalytic Annulation of Azonaphthalenes: An Access to Indole Derivatives

Drugs for the Treatment of Zika Virus Infection

Marinopyrrole derivatives with sulfide spacers as selective disruptors of Mcl-1 binding to pro-apoptotic protein Bim

Marinopyrrole derivatives as potential antibiotic agents against methicillin-resistant Staphylococcus aureus (I)

Design and Synthesis of 5-Aryl-pyridone-carboxamides as Inhibitors of Anaplastic Lymphoma Kinase

Marine natural products based drug discoveries

In Vitro Antimalarial Activity of Chalcones and Their Derivatives

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