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Emicizumab and thrombosis: The story so far

Journal of thrombosis and haemostasis, 2019-08, Vol.17 (8), p.1269-1272

2019

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von Willebrand factor biosynthesis, secretion, and clearance: connecting the far ends

Blood, 2015-03, Vol.125 (13), p.2019-2028

2015

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Laboratory monitoring of hemophilia A treatments: new challenges

Blood advances, 2020-05, Vol.4 (9), p.2111-2118

Lenting, Peter J.

2020

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Ex vivo editing of human hematopoietic stem cells for erythroid expression of therapeutic proteins

Nature communications, 2020-07, Vol.11 (1), p.3778-3778, Article 3778

2020

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Arterial Pulsatility and Circulating von Willebrand Factor in Patients on Mechanical Circulatory Support

Journal of the American College of Cardiology, 2018-05, Vol.71 (19), p.2106-2118

2018

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How to keep the factor VIII/von Willebrand factor complex in the circulation

Haematologica (Roma), 2021-11, Vol.107 (9), p.2011-2013

2021

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Differences in venous clot structures between hemophilic mice treated with emicizumab versus factor VIII or factor VIIIFc

Haematologica (Roma), 2024-06, Vol.109 (6), p.1836

2024

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The von Willebrand Factor A1 domain mediates thromboinflammation, aggravating ischemic stroke outcome in mice

Haematologica (Roma), 2021-03, Vol.106 (3), p.819-828

2021

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Macrophage scavenger receptor SR-AI contributes to the clearance of von Willebrand factor

Haematologica (Roma), 2018-04, Vol.103 (4), p.728-737

2018

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Correction of bleeding in experimental severe hemophilia A by systemic delivery of factor VIII-encoding mRNA

Haematologica (Roma), 2020-04, Vol.105 (4), p.1129-1137

2020

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Author Correction: Ex vivo editing of human hematopoietic stem cells for erythroid expression of therapeutic proteins

Nature communications, 2020-08, Vol.11 (1), p.4146-4146, Article 4146

2020

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Non-inhibitory antibodies inducing increased emicizumab clearance in a severe haemophilia A inhibitor patient

Haematologica (Roma), 2021-05, Vol.106 (8), p.2287-2290

2021

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PBPK modeling of recombinant factor IX Fc fusion protein (rFIXFc) and rFIX to characterize the binding to type 4 collagen in the extravascular space

CPT: pharmacometrics and systems pharmacology, 2024-10, Vol.13 (10), p.1630-1640

2024

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Macrophage LRP1 contributes to the clearance of von Willebrand factor

Blood, 2012-03, Vol.119 (9), p.2126-2134

2012

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von Willebrand Factor as a Biological Sensor of Blood Flow to Monitor Percutaneous Aortic Valve Interventions

Circulation research, 2015-03, Vol.116 (7), p.1193-1201

2015

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Monoclonal gammopathy of clinical significance: in vivo demonstration of the anti-thrombotic effect of an acquired anti-thrombin antibody

Haematologica (Roma), 2021-01, Vol.106 (1), p.316-319

2021

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New class of monoclonal antibodies against severe influenza: prophylactic and therapeutic efficacy in ferrets

PloS one, 2010-02, Vol.5 (2), p.e9106-e9106

2010

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Factor VIII and von Willebrand factor are ligands for the carbohydrate-receptor Siglec-5

Haematologica (Roma), 2012-12, Vol.97 (12), p.1855-1863

2012

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Accelerated uptake of VWF/platelet complexes in macrophages contributes to VWD type 2B–associated thrombocytopenia

Blood, 2013-10, Vol.122 (16), p.2893-2902

2013

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Transient von Willebrand factor‐mediated platelet influx stimulates liver regeneration after partial hepatectomy in mice

Liver international, 2017-11, Vol.37 (11), p.1731-1737

2017

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In vivo analysis of the role of O-glycosylations of von Willebrand factor

PloS one, 2012-05, Vol.7 (5), p.e37508-e37508

2012

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Emicizumab, a bispecific antibody recognizing coagulation factors IX and X: how does it actually compare to factor VIII?

Blood, 2017-12, Vol.130 (23), p.2463-2468

2017

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Collagens are functional, high affinity ligands for the inhibitory immune receptor LAIR-1

The Journal of experimental medicine, 2006-06, Vol.203 (6), p.1419-1425

2006

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von Willebrand factor: from figurant to main character in the scene of inflammation

Journal of thrombosis and haemostasis, 2023-04, Vol.21 (4), p.710-713

2023

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Emicizumab and thrombosis: The story so far

von Willebrand factor biosynthesis, secretion, and clearance: connecting the far ends

Laboratory monitoring of hemophilia A treatments: new challenges

Ex vivo editing of human hematopoietic stem cells for erythroid expression of therapeutic proteins

Arterial Pulsatility and Circulating von Willebrand Factor in Patients on Mechanical Circulatory Support

How to keep the factor VIII/von Willebrand factor complex in the circulation

Differences in venous clot structures between hemophilic mice treated with emicizumab versus factor VIII or factor VIIIFc

Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variant

The von Willebrand Factor A1 domain mediates thromboinflammation, aggravating ischemic stroke outcome in mice

Macrophage scavenger receptor SR-AI contributes to the clearance of von Willebrand factor

Correction of bleeding in experimental severe hemophilia A by systemic delivery of factor VIII-encoding mRNA

Author Correction: Ex vivo editing of human hematopoietic stem cells for erythroid expression of therapeutic proteins

Non-inhibitory antibodies inducing increased emicizumab clearance in a severe haemophilia A inhibitor patient

PBPK modeling of recombinant factor IX Fc fusion protein (rFIXFc) and rFIX to characterize the binding to type 4 collagen in the extravascular space

Macrophage LRP1 contributes to the clearance of von Willebrand factor

von Willebrand Factor as a Biological Sensor of Blood Flow to Monitor Percutaneous Aortic Valve Interventions

Monoclonal gammopathy of clinical significance: in vivo demonstration of the anti-thrombotic effect of an acquired anti-thrombin antibody

New class of monoclonal antibodies against severe influenza: prophylactic and therapeutic efficacy in ferrets

Factor VIII and von Willebrand factor are ligands for the carbohydrate-receptor Siglec-5

Accelerated uptake of VWF/platelet complexes in macrophages contributes to VWD type 2B–associated thrombocytopenia

Transient von Willebrand factor‐mediated platelet influx stimulates liver regeneration after partial hepatectomy in mice

In vivo analysis of the role of O-glycosylations of von Willebrand factor

Emicizumab, a bispecific antibody recognizing coagulation factors IX and X: how does it actually compare to factor VIII?

Collagens are functional, high affinity ligands for the inhibitory immune receptor LAIR-1

von Willebrand factor: from figurant to main character in the scene of inflammation

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