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Transcriptome Profiling of Mouse Embryonic Fibroblast Spontaneous Immortalization: A Comparative Analysis

International journal of molecular sciences, 2024-08, Vol.25 (15), p.8116

2024

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Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions

Cell reports (Cambridge), 2016-03, Vol.14 (10), p.2325-2336

2016

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T cell-intrinsic protein kinase D3 is dispensable for the cells' activation

Frontiers in immunology, 2022-11, Vol.13, p.1049033-1049033

2022

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WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis

The Journal of clinical investigation, 2021-08, Vol.131 (16), p.1-15

2021

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Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia

Nature communications, 2015-02, Vol.6 (1), p.6200-6200, Article 6200

2015

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Role of Integrins α1β1 and α2β1 in Wound and Tumor Angiogenesis in Mice

The American journal of pathology, 2016-11, Vol.186 (11), p.3011-3027

2016

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Repression of Intestinal Stem Cell Function and Tumorigenesis through Direct Phosphorylation of β-Catenin and Yap by PKCζ

Cell reports (Cambridge), 2015-02, Vol.10 (5), p.740-754

2015

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Redundant role of protein kinase C delta and epsilon during mouse embryonic development

PloS one, 2014-08, Vol.9 (8), p.e103686-e103686

2014

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Investigations of mouse models during tumorigenesis revealed essential but distinct in vivo functions among the PKC family

Advances in biological regulation, 2020-12, Vol.78, p.100756-100756, Article 100756

Leitges, Michael

2020

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Control of Paneth Cell Fate, Intestinal Inflammation, and Tumorigenesis by PKCλ/ι

Cell reports (Cambridge), 2016-09, Vol.16 (12), p.3297-3310

2016

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Multiple endothelial cells constitute the tip of developing blood vessels and polarize to promote lumen formation

Development (Cambridge), 2014-11, Vol.141 (21), p.4121-4126

2014

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The Atypical PKC-Interacting Protein p62 Is an Important Mediator of RANK-Activated Osteoclastogenesis

Developmental cell, 2004-02, Vol.6 (2), p.303-309

2004

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12R-lipoxygenase deficiency disrupts epidermal barrier function

The Journal of cell biology, 2007-04, Vol.177 (1), p.173-182

2007

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Addressing the role of PKD3 in the T cell compartment with knockout mice

Cell communication and signaling, 2022-04, Vol.20 (1), p.54-54, Article 54

2022

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Novel mutant mouse line emphasizes the importance of protein kinase C theta for CD4 + T lymphocyte activation

Cell communication and signaling, 2019-05, Vol.17 (1), p.56-56, Article 56

2019

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PKCβ phosphorylates PI3Kγ to activate it and release it from GPCR control

PLoS biology, 2013-06, Vol.11 (6), p.e1001587

2013

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Prkci Regulates Autophagy and Pancreatic Tumorigenesis in Mice

Cancers, 2022-02, Vol.14 (3), p.796

2022

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c-Myc phosphorylation by PKCζ represses prostate tumorigenesis

Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (16), p.6418-6423

2013

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Control of oxidative phosphorylation by vitamin A illuminates a fundamental role in mitochondrial energy homoeostasis

The FASEB journal, 2010-02, Vol.24 (2), p.627-636

2010

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Podocytic PKC-alpha is regulated in murine and human diabetes and mediates nephrin endocytosis

PloS one, 2010-04, Vol.5 (4), p.e10185-e10185

2010

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Calcium-Dependent Isoforms of Protein Kinase C Mediate Posttetanic Potentiation at the Calyx of Held

Neuron (Cambridge, Mass.), 2011-06, Vol.70 (5), p.1005-1019

2011

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Loss-of-function phenotype of a PKCθ T219A knockin mouse strain

Cell communication and signaling, 2019-11, Vol.17 (1), p.141-141, Article 141

2019

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Deletion of Protein Kinase C-β Isoform In Vivo Reduces Renal Hypertrophy but Not Albuminuria in the Streptozotocin-Induced Diabetic Mouse Model

Diabetes (New York, N.Y.), 2007-02, Vol.56 (2), p.346-354

2007

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Isozyme-specific Effects of Protein Kinase C in Pain Modulation

Anesthesiology (Philadelphia), 2011-12, Vol.115 (6), p.1261-1270

2011

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Transcriptome Profiling of Mouse Embryonic Fibroblast Spontaneous Immortalization: A Comparative Analysis

Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions

T cell-intrinsic protein kinase D3 is dispensable for the cells' activation

WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis

Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia

Role of Integrins α1β1 and α2β1 in Wound and Tumor Angiogenesis in Mice

Repression of Intestinal Stem Cell Function and Tumorigenesis through Direct Phosphorylation of β-Catenin and Yap by PKCζ

Redundant role of protein kinase C delta and epsilon during mouse embryonic development

Investigations of mouse models during tumorigenesis revealed essential but distinct in vivo functions among the PKC family

Control of Paneth Cell Fate, Intestinal Inflammation, and Tumorigenesis by PKCλ/ι

AHI1 is required for photoreceptor outer segment development and is a modifier for retinal degeneration in nephronophthisis

Multiple endothelial cells constitute the tip of developing blood vessels and polarize to promote lumen formation

The Atypical PKC-Interacting Protein p62 Is an Important Mediator of RANK-Activated Osteoclastogenesis

12R-lipoxygenase deficiency disrupts epidermal barrier function

Addressing the role of PKD3 in the T cell compartment with knockout mice

Novel mutant mouse line emphasizes the importance of protein kinase C theta for CD4 + T lymphocyte activation

PKCβ phosphorylates PI3Kγ to activate it and release it from GPCR control

Prkci Regulates Autophagy and Pancreatic Tumorigenesis in Mice

c-Myc phosphorylation by PKCζ represses prostate tumorigenesis

Control of oxidative phosphorylation by vitamin A illuminates a fundamental role in mitochondrial energy homoeostasis

Podocytic PKC-alpha is regulated in murine and human diabetes and mediates nephrin endocytosis

Calcium-Dependent Isoforms of Protein Kinase C Mediate Posttetanic Potentiation at the Calyx of Held

Loss-of-function phenotype of a PKCθ T219A knockin mouse strain

Deletion of Protein Kinase C-β Isoform In Vivo Reduces Renal Hypertrophy but Not Albuminuria in the Streptozotocin-Induced Diabetic Mouse Model

Isozyme-specific Effects of Protein Kinase C in Pain Modulation

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