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Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species

Journal of cell science, 2014-03, Vol.127 (Pt 6), p.1263-1278

2014

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Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic

Cell reports (Cambridge), 2013-12, Vol.5 (5), p.1178-1186

2013

Volltextzugriff (PDF)

The increasing diversity of functions attributed to the SAFB family of RNA-/DNA-binding proteins

Biochemical journal, 2016-12, Vol.473 (23), p.4271-4288

2016

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MicroRNA-132 regulates recognition memory and synaptic plasticity in the perirhinal cortex

The European journal of neuroscience, 2012-10, Vol.36 (7), p.2941-2948

2012

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Cytoplasmic TDP-43 is involved in cell fate during stress recovery

Human molecular genetics, 2021-12, Vol.31 (2), p.166-175

2021

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C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity

Human molecular genetics, 2017-12, Vol.26 (24), p.4765-4777

2017

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Twist-1 regulates the miR-199a/214 cluster during development

Nucleic acids research, 2009-01, Vol.37 (1), p.123

2009

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Nuclear RNA foci from C9ORF72 expansion mutation form paraspeckle-like bodies

Journal of cell science, 2019-03, Vol.132 (5)

2019

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RNA Misprocessing in C9orf72 -Linked Neurodegeneration

Frontiers in cellular neuroscience, 2017-07, Vol.11, p.195-195

2017

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Allele-specific knockdown of ALS-associated mutant TDP-43 in neural stem cells derived from induced pluripotent stem cells

PloS one, 2014-03, Vol.9 (3), p.e91269

2014

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iCLIP identifies novel roles for SAFB1 in regulating RNA processing and neuronal function

BMC biology, 2015-12, Vol.13 (110), p.111-111, Article 111

2015

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Muscarinic receptors induce LTD of NMDAR EPSCs via a mechanism involving hippocalcin, AP2 and PSD-95

Nature neuroscience, 2010-10, Vol.13 (10), p.1216-1224

2010

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Retention of hexanucleotide repeat-containing intron in C9orf72 mRNA: implications for the pathogenesis of ALS/FTD

Acta neuropathologica communications, 2016-02, Vol.4 (18), p.18, Article 18

2016

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A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration

Brain (London, England : 1878), 2018-10, Vol.141 (10), p.2908-2924

2018

Volltextzugriff (PDF)

Interactome screening of C9orf72 dipeptide repeats reveals VCP sequestration and functional impairment by polyGA

Brain (London, England : 1878), 2022-04, Vol.145 (2), p.684-699

2022

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Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their degeneration

Acta neuropathologica communications, 2015-06, Vol.3 (1), p.38, Article 38

2015

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Mutations in FUS lead to synaptic dysregulation in ALS-iPSC derived neurons

Stem cell reports, 2024-02, Vol.19 (2), p.187-195

2024

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SAFB re-distribution marks steps of the apoptotic process

Experimental cell research, 2007-11, Vol.313 (18), p.3914-3923

2007

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Phosphorylation of C-terminal tyrosine residue 526 in FUS impairs its nuclear import

Journal of cell science, 2015-11, Vol.128 (22), p.4151-4159

2015

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A serum microRNA signature for amyotrophic lateral sclersosis reveals convergent RNA processing defects and identifies presymptomatic mutation carriers

Brain (London, England : 1878), 2014-11, Vol.137 (Pt 11), p.2875-2876

2014

Volltextzugriff (PDF)

Optimizing regulatable gene expression using adenoviral vectors

Experimental physiology, 2005-01, Vol.90 (1), p.33-37

2005

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Using viral vectors as gene transfer tools (Cell Biology and Toxicology Special Issue: ETCS-UK 1 day meeting on genetic manipulation of cells)

Cell biology and toxicology, 2010-02, Vol.26 (1), p.1-20

2010

Volltextzugriff (PDF)

Increased utility in the CNS of a powerful neuron-specific tetracycline-regulatable adenoviral system developed using a post-transcriptional enhancer

The journal of gene medicine, 2005-05, Vol.7 (5), p.576-583

2005

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Depletion of mitochondrial DNA alters glucose metabolism in SK-Hep1 cells

American journal of physiology: endocrinology and metabolism, 2001-06, Vol.280 (6), p.E1007-E1014

2001

Volltextzugriff (PDF)

Phosphorylation of C-terminal tyrosine 526 in FUS impairs its nuclear import

Journal of cell science, 2015-01

2015

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Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species

Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic

The increasing diversity of functions attributed to the SAFB family of RNA-/DNA-binding proteins

MicroRNA-132 regulates recognition memory and synaptic plasticity in the perirhinal cortex

Cytoplasmic TDP-43 is involved in cell fate during stress recovery

C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity

Twist-1 regulates the miR-199a/214 cluster during development

Nuclear RNA foci from C9ORF72 expansion mutation form paraspeckle-like bodies

RNA Misprocessing in C9orf72 -Linked Neurodegeneration

Allele-specific knockdown of ALS-associated mutant TDP-43 in neural stem cells derived from induced pluripotent stem cells

iCLIP identifies novel roles for SAFB1 in regulating RNA processing and neuronal function

Muscarinic receptors induce LTD of NMDAR EPSCs via a mechanism involving hippocalcin, AP2 and PSD-95

Retention of hexanucleotide repeat-containing intron in C9orf72 mRNA: implications for the pathogenesis of ALS/FTD

A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration

Interactome screening of C9orf72 dipeptide repeats reveals VCP sequestration and functional impairment by polyGA

Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their degeneration

Mutations in FUS lead to synaptic dysregulation in ALS-iPSC derived neurons

SAFB re-distribution marks steps of the apoptotic process

Phosphorylation of C-terminal tyrosine residue 526 in FUS impairs its nuclear import

A serum microRNA signature for amyotrophic lateral sclersosis reveals convergent RNA processing defects and identifies presymptomatic mutation carriers

Optimizing regulatable gene expression using adenoviral vectors

Using viral vectors as gene transfer tools (Cell Biology and Toxicology Special Issue: ETCS-UK 1 day meeting on genetic manipulation of cells)

Increased utility in the CNS of a powerful neuron-specific tetracycline-regulatable adenoviral system developed using a post-transcriptional enhancer

Depletion of mitochondrial DNA alters glucose metabolism in SK-Hep1 cells

Phosphorylation of C-terminal tyrosine 526 in FUS impairs its nuclear import

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