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Impact of Tumour Hypoxia on Evofosfamide Sensitivity in Head and Neck Squamous Cell Carcinoma Patient-Derived Xenograft Models

Cells (Basel, Switzerland), 2019-07, Vol.8 (7), p.717

2019

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Radiosensitization of head and neck squamous cell carcinoma lines by DNA-PK inhibitors is more effective than PARP-1 inhibition and is enhanced by SLFN11 and hypoxia

International journal of radiation biology, 2019-12, Vol.95 (12), p.1597-1612

2019

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Clinical relevance and therapeutic predictive ability of hypoxia biomarkers in head and neck cancer tumour models

Molecular oncology, 2024-08, Vol.18 (8), p.1885-1903

2024

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Patient-Derived Xenograft and Organoid Models for Precision Medicine Targeting of the Tumour Microenvironment in Head and Neck Cancer

Cancers, 2020-12, Vol.12 (12), p.3743

2020

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Expression of the serine protease inhibitor neuroserpin in cells of the human myeloid lineage

Thrombosis and haemostasis, 2007-03, Vol.97 (3), p.394

2007

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The serine protease inhibitor neuroserpin regulates the growth and maturation of hippocampal neurons through a non-inhibitory mechanism

Journal of neurochemistry, 2012-05, Vol.121 (3-4), p.561-574

2012

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Neuroserpin regulates N-cadherin-mediated cell adhesion independently of its activity as an inhibitor of tissue plasminogen activator

Journal of neuroscience research, 2008-05, Vol.86 (6), p.1243-1253

2008

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Retracted: The serine protease inhibitor neuroserpin regulates the growth and maturation of hippocampal neurons through a non-inhibitory mechanism

Journal of neurochemistry, 2012-05, Vol.121 (4), p.561-574

2012

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Physiological and pathological functions of neuroserpin: Regulation of cellular responses through multiple mechanisms

Seminars in cell & developmental biology, 2017-02, Vol.62, p.152-159

2017

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Abstract 3561: HIF-1α stabilisation in triple receptor negative breast cancer is sensitive to glutaminase inhibition

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.3561-3561

2020

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Abstract 5853: Identification of TSC1 and TSC2 as potential determinants of sensitivity to trastuzumab emtansine

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.5853-5853

2020

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Clonal dynamics limits detection of selection in tumour xenograft CRISPR/Cas9 screens

Cancer gene therapy, 2023-12, Vol.30 (12), p.1610-1623

2023

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Fragment-based and structure-guided discovery of perforin inhibitors

European journal of medicinal chemistry, 2023-12, Vol.261, p.115786-115786, Article 115786

2023

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Physiological and pathological roles of tissue plasminogen activator and its inhibitor neuroserpin in the nervous system

Frontiers in cellular neuroscience, 2015-10, Vol.9, p.396-396

2015

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Chemicals eluting from disposable plastic syringes and syringe filters alter neurite growth, axogenesis and the microtubule cytoskeleton in cultured hippocampal neurons

Journal of neurochemistry, 2015-04, Vol.133 (1), p.53-65

2015

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An analysis approach to identify specific functional sites in orthologous proteins using sequence and structural information: Application to neuroserpin reveals regions that differentially regulate inhibitory activity

Proteins, structure, function, and bioinformatics, 2015-01, Vol.83 (1), p.135-152

2015

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Abstract 169: Preclinical efficacy and sensitivity determinants of evofosfamide in molecularly defined models of head and neck squamous cell carcinoma

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.169-169

2017

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Tissue plasminogen activator inhibits NMDA-receptor-mediated increases in calcium levels in cultured hippocampal neurons

Frontiers in cellular neuroscience, 2015-10, Vol.9, p.404-404

2015

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Synaptic plasticity-associated proteases and protease inhibitors in the brain linked to the processing of extracellular matrix and cell adhesion molecules

Neuron glia biology, 2008-08, Vol.4 (3), p.223

2008

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Head And Neck Squamous Cell Carcinoma
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Impact of Tumour Hypoxia on Evofosfamide Sensitivity in Head and Neck Squamous Cell Carcinoma Patient-Derived Xenograft Models

Radiosensitization of head and neck squamous cell carcinoma lines by DNA-PK inhibitors is more effective than PARP-1 inhibition and is enhanced by SLFN11 and hypoxia

Clinical relevance and therapeutic predictive ability of hypoxia biomarkers in head and neck cancer tumour models

Patient-Derived Xenograft and Organoid Models for Precision Medicine Targeting of the Tumour Microenvironment in Head and Neck Cancer

Expression of the serine protease inhibitor neuroserpin in cells of the human myeloid lineage

The serine protease inhibitor neuroserpin regulates the growth and maturation of hippocampal neurons through a non-inhibitory mechanism

Neuroserpin regulates N-cadherin-mediated cell adhesion independently of its activity as an inhibitor of tissue plasminogen activator

Retracted: The serine protease inhibitor neuroserpin regulates the growth and maturation of hippocampal neurons through a non-inhibitory mechanism

Physiological and pathological functions of neuroserpin: Regulation of cellular responses through multiple mechanisms

Abstract 3561: HIF-1α stabilisation in triple receptor negative breast cancer is sensitive to glutaminase inhibition

Abstract 5853: Identification of TSC1 and TSC2 as potential determinants of sensitivity to trastuzumab emtansine

Clonal dynamics limits detection of selection in tumour xenograft CRISPR/Cas9 screens

Fragment-based and structure-guided discovery of perforin inhibitors

Physiological and pathological roles of tissue plasminogen activator and its inhibitor neuroserpin in the nervous system

Chemicals eluting from disposable plastic syringes and syringe filters alter neurite growth, axogenesis and the microtubule cytoskeleton in cultured hippocampal neurons

An analysis approach to identify specific functional sites in orthologous proteins using sequence and structural information: Application to neuroserpin reveals regions that differentially regulate inhibitory activity

Abstract 169: Preclinical efficacy and sensitivity determinants of evofosfamide in molecularly defined models of head and neck squamous cell carcinoma

Tissue plasminogen activator inhibits NMDA-receptor-mediated increases in calcium levels in cultured hippocampal neurons

Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma

Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma

Synaptic plasticity-associated proteases and protease inhibitors in the brain linked to the processing of extracellular matrix and cell adhesion molecules

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