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Phase separation of Polo-like kinase 4 by autoactivation and clustering drives centriole biogenesis

Nature communications, 2019-10, Vol.10 (1), p.4959-19, Article 4959

2019

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Recent Advances and New Strategies in Targeting Plk1 for Anticancer Therapy

Trends in pharmacological sciences (Regular ed.), 2015-12, Vol.36 (12), p.858-877

2015

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Control of the pericentrosomal H2O2 level by peroxiredoxin I is critical for mitotic progression

The Journal of cell biology, 2015-07, Vol.210 (1), p.23-33

2015

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Hierarchical recruitment of Plk4 and regulation of centriole biogenesis by two centrosomal scaffolds, Cep192 and Cep152

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (50), p.E4849-E4857

2013

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Requirement of the Cep57-Cep63 Interaction for Proper Cep152 Recruitment and Centriole Duplication

Molecular and cellular biology, 2020-04, Vol.40 (10), p.1-17

2020

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Polo-box domain: a versatile mediator of polo-like kinase function

Cellular and molecular life sciences : CMLS, 2010-06, Vol.67 (12), p.1957-1970

2010

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Molecular architecture of a cylindrical self-assembly at human centrosomes

Nature communications, 2019-03, Vol.10 (1), p.1151-1151, Article 1151

2019

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Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4+ T cells

Nature communications, 2024-03, Vol.15 (1), p.2017-2017, Article 2017

2024

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Anticancer activity of a novel small molecule tubulin inhibitor STK899704

PloS one, 2017-03, Vol.12 (3), p.e0173311

2017

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Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis

Nature structural & molecular biology, 2014-08, Vol.21 (8), p.696-703

2014

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Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel

Nature chemical biology, 2011-07, Vol.7 (9), p.595-601

2011

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Bimodal Interaction of Mammalian Polo-Like Kinase 1 and a Centrosomal Scaffold, Cep192, in the Regulation of Bipolar Spindle Formation

Molecular and cellular biology, 2015-08, Vol.35 (15), p.2626-2640

2015

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ER-associated CTRP1 regulates mitochondrial fission via interaction with DRP1

Experimental and Molecular Medicine, 2021, 53(0), , pp.1-12

2021

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Design and synthesis of a cell-permeable, drug-like small molecule inhibitor targeting the polo-box domain of polo-like kinase 1

PloS one, 2014-09, Vol.9 (9), p.e107432-e107432

2014

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Nonspecific interstitial pneumonia and idiopathic pulmonary fibrosis: changes in pattern and distribution of disease over time

Radiology, 2008-04, Vol.247 (1), p.251-259

2008

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Self-Regulated Plk1 Recruitment to Kinetochores by the Plk1-PBIP1 Interaction Is Critical for Proper Chromosome Segregation

Molecular cell, 2006-11, Vol.24 (3), p.409-422

2006

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Regulation of microtubule-based microtubule nucleation by mammalian polo-like kinase 1

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (28), p.11446-11451

2011

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Selective blockade of cancer cell proliferation and anchorage-independent growth by Plk1 activity-dependent suicidal inhibition of its polo-box domain

Cell cycle (Georgetown, Tex.), 2015-11, Vol.14 (22), p.3624-3634

2015

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A self-assembled cylindrical platform for Plk4-induced centriole biogenesis

Open biology, 2020-08, Vol.10 (8), p.200102-200102

2020

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BRCA1 downregulates the kinase activity of Polo-like kinase 1 in response to replication stress

Cell cycle (Georgetown, Tex.), 2013-07, Vol.12 (14), p.2255-2265

2013

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Identification of High Affinity Polo-like Kinase 1 (Plk1) Polo-box Domain Binding Peptides Using Oxime-Based Diversification

ACS chemical biology, 2012-05, Vol.7 (5), p.805-810

2012

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Mammalian Polo-like Kinase 1 (Plk1) Promotes Proper Chromosome Segregation by Phosphorylating and Delocalizing the PBIP1·CENP-Q Complex from Kinetochores

The Journal of biological chemistry, 2015-03, Vol.290 (13), p.8569-8581

2015

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The yeast Tor signaling pathway is involved in G2/M transition via polo-kinase

PloS one, 2008-05, Vol.3 (5), p.e2223-e2223

2008

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Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1

Bioorganic & medicinal chemistry, 2013-05, Vol.21 (9), p.2623-2634

2013

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Mono-anionic phosphopeptides produced by unexpected histidine alkylation exhibit high plk1 polo-box domain-binding affinities and enhanced antiproliferative effects in hela cells

Biopolymers, 2014-11, Vol.102 (6), p.444-455

2014

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Phase separation of Polo-like kinase 4 by autoactivation and clustering drives centriole biogenesis

Recent Advances and New Strategies in Targeting Plk1 for Anticancer Therapy

Control of the pericentrosomal H2O2 level by peroxiredoxin I is critical for mitotic progression

Hierarchical recruitment of Plk4 and regulation of centriole biogenesis by two centrosomal scaffolds, Cep192 and Cep152

Requirement of the Cep57-Cep63 Interaction for Proper Cep152 Recruitment and Centriole Duplication

Polo-box domain: a versatile mediator of polo-like kinase function

Molecular architecture of a cylindrical self-assembly at human centrosomes

Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4+ T cells

Anticancer activity of a novel small molecule tubulin inhibitor STK899704

Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis

Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel

Bimodal Interaction of Mammalian Polo-Like Kinase 1 and a Centrosomal Scaffold, Cep192, in the Regulation of Bipolar Spindle Formation

ER-associated CTRP1 regulates mitochondrial fission via interaction with DRP1

Design and synthesis of a cell-permeable, drug-like small molecule inhibitor targeting the polo-box domain of polo-like kinase 1

Nonspecific interstitial pneumonia and idiopathic pulmonary fibrosis: changes in pattern and distribution of disease over time

Self-Regulated Plk1 Recruitment to Kinetochores by the Plk1-PBIP1 Interaction Is Critical for Proper Chromosome Segregation

Regulation of microtubule-based microtubule nucleation by mammalian polo-like kinase 1

Selective blockade of cancer cell proliferation and anchorage-independent growth by Plk1 activity-dependent suicidal inhibition of its polo-box domain

A self-assembled cylindrical platform for Plk4-induced centriole biogenesis

BRCA1 downregulates the kinase activity of Polo-like kinase 1 in response to replication stress

Identification of High Affinity Polo-like Kinase 1 (Plk1) Polo-box Domain Binding Peptides Using Oxime-Based Diversification

Mammalian Polo-like Kinase 1 (Plk1) Promotes Proper Chromosome Segregation by Phosphorylating and Delocalizing the PBIP1·CENP-Q Complex from Kinetochores

The yeast Tor signaling pathway is involved in G2/M transition via polo-kinase

Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1

Mono-anionic phosphopeptides produced by unexpected histidine alkylation exhibit high plk1 polo-box domain-binding affinities and enhanced antiproliferative effects in hela cells

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