UB Paderborn / Katalog / Suche / in CDI

Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist gegebenenfalls nur via VPN oder Shibboleth (DFN-AAI) möglich. mehr Informationen...

1 – 25 von 2.323

Sortiert nach

The ALK inhibitor ceritinib overcomes crizotinib resistance in non-small cell lung cancer

Cancer discovery, 2014-06, Vol.4 (6), p.662-673

2014

Volltextzugriff (PDF)

Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain

Biochemical journal, 2010-09, Vol.430 (3), p.425-437

2010

Volltextzugriff (PDF)

Discovery and Profiling of a Selective and Efficacious Syk Inhibitor

Journal of medicinal chemistry, 2015-02, Vol.58 (4), p.1950-1963

2015

Volltextzugriff (PDF)

Synthesis, Structure–Activity Relationships, and in Vivo Efficacy of the Novel Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor 5‑Chloro‑N2‑(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)‑N4‑(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) Currently in Phase 1 and Phase 2 Clinical Trials

Journal of medicinal chemistry, 2013-07, Vol.56 (14), p.5675-5690

2013

Volltextzugriff (PDF)

Crystal Structure of the Human Neuropilin-1 b1 Domain

Structure (London), 2003, Vol.11 (1), p.99-108

2003

Volltextzugriff (PDF)

Divalent Cations Slow Activation of EAG Family K+ Channels through Direct Binding to S4

Biophysical journal, 2009-07, Vol.97 (1), p.110-120

2009

Volltextzugriff (PDF)

A Conserved Salt Bridge in the G Loop of Multiple Protein Kinases Is Important for Catalysis and for In Vivo Lyn Function

Molecular cell, 2009-01, Vol.33 (1), p.43-52

2009

Volltextzugriff (PDF)

Design and synthesis of 7H-pyrrolo[2,3-d]pyrimidines as focal adhesion kinase inhibitors. Part 2

Bioorganic & medicinal chemistry letters, 2006-05, Vol.16 (10), p.2689-2692

2006

Volltextzugriff (PDF)

Orally bioavailable Syk inhibitors with activity in a rat PK/PD model

Bioorganic & medicinal chemistry letters, 2015-10, Vol.25 (20), p.4642-4647

2015

Volltextzugriff (PDF)

Syk inhibitors with high potency in presence of blood

Bioorganic & medicinal chemistry letters, 2014-05, Vol.24 (10), p.2278-2282

2014

Volltextzugriff (PDF)

How does conformational flexibility influence key structural features involved in activation of anaplastic lymphoma kinase?

Molecular bioSystems, 2014-01, Vol.10 (6), p.1490-1495

2014

Volltextzugriff (PDF)

Crystal Structure of the Type III Effector AvrB from Pseudomonas syringae

Structure (London), 2004-03, Vol.12 (3), p.487-494

2004

Volltextzugriff (PDF)

Investigation of the functional role of active site loop II in a hypoxanthine phosphoribosyltransferase

Biochimica et biophysica acta, 2001-07, Vol.1537 (1), p.63-70

2001

Volltextzugriff (PDF)

Synthesis, Structure–Activity Relationships, and in Vivo Efficacy of the Novel Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor 5-Chloro- N 2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)- N 4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) Currently in Phase 1 and Phase 2 Clinical Trials

Journal of medicinal chemistry, 2013-07, Vol.56 (14), p.5675-5690

2013

Volltextzugriff (PDF)

Transesophageal Echocardiography and the Intraoperative Diagnosis of a Right Pulmonary Artery Aneurysm

Journal of cardiothoracic and vascular anesthesia, 2006-08, Vol.20 (4), p.562-564

2006

Volltextzugriff (PDF)

Crystal structure of an Udp-n-acetylmuramate-alanine ligase MurC (TM0231) from Thermotoga maritima at 2.3 Å resolution

Proteins, structure, function, and bioinformatics, 2004-06, Vol.55 (4), p.1078-1081

2004

Volltextzugriff (PDF)

How does conformational flexibility influence key structural features involved in activation of anaplastic lymphoma kinase?Electronic supplementary information (ESI) available. See DOI: 10.1039/c4mb00141a

2014-05

Volltextzugriff (PDF)

A Single Amino Acid Substitution in the Human and a Bacterial Hypoxanthine Phosphoribosyltransferase Modulates Specificity for the Binding of Guanine

Biochemistry (Easton), 1998-03, Vol.37 (10), p.3491-3498

1998

Volltextzugriff (PDF)

Abstract 957: The ALK inhibitor LDK378 overcomes crizotinib resistance in non-small cell lung cancer

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.957-957

2014

Volltextzugriff (PDF)

Direct Binding Of Divalent Cations To The S4 Region In Eag Family K+ Channels Reveals A Closed Conformation Shared With Kv1 Channels

Biophysical journal, 2009-02, Vol.96 (3), p.188a-188a

2009

Volltextzugriff (PDF)

A conserved salt bridge in the G-loop of multiple protein kinases is essential for catalysis, in vivo Lyn function and prevention of autoimmune disease (84.17)

The Journal of immunology (1950), 2009-04, Vol.182 (1_Supplement), p.84-84.17

2009

Volltextzugriff (PDF)

Cytotoxicity of ferratricarbadecaboranyl complexes in murine and human tissue cultured cell lines

Anticancer research, 1998-03, Vol.18 (2A), p.951

1998

Volltextzugriff (PDF)

Cytotoxicity of Metallic Complexes of Furan Oximes in Murine and Human Tissue Cultured Cell Lines

Applied organometallic chemistry, 1997-07, Vol.11 (7), p.565-575

1997

Volltextzugriff (PDF)

Kationische Metallatricarbadecaboranyl-Analoga von Metallocen-Cytostatica: Synthese, Struktur und antineoplastische Aktivitäten von [1-(η5-C5H5)Fe-2-Me-2,3,4-C3B7H9]+-Salzen (Gegenionen: AsF6−, SbF6−)

Angewandte Chemie, 1997-10, Vol.109 (20), p.2300-2302

1997

Volltextzugriff (PDF)

Structure-function studies of hypoxanthine phosphoribosyltransferases: A structural determinant for substrate specificity and involvement of a flexible loop in catalysis

Lee, Christian C

1999

Volltextzugriff (PDF)

1 – 25 von 2.323

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(2.041)
Mit Volltextzugriff
(2.068)

Publikationsform

4 weitere anzeigen...

Weniger anzeigen...

Sprache

3 weitere anzeigen...

Weniger anzeigen...

Erscheinungsjahr

n.n

n.n

Thema

Science & Technology
(1.749)
Life Sciences & Biomedicine
(1.166)
Humans
(878)
Female
(460)
Male
(452)
Technology
(313)
Physical Sciences
(305)
Animals
(292)
Adult
(243)
Biological And Medical Sciences
(242)
Middle Aged
(240)
Computer Science
(191)
Aged
(185)
Medical Sciences
(177)
Physics
(165)
Neurosciences & Neurology
(154)
Mice
(142)
Science & Technology - Other Topics
(138)
Multidisciplinary Sciences
(121)
Biochemistry & Molecular Biology
(118)

15 weitere anzeigen...

Weniger anzeigen...

Kollektion

EZB*
(1.109)
MEDLINE
(1.104)
Ingenta
(942)
Journals@Ovid Full Text
(654)
NUS Single-Journal Subscriptions
(572)
Access via ScienceDirect (Elsevier)
(366)
IngentaConnect Journals
(357)
Access via Wiley Online Library
(236)
Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)
(231)
IEEE Electronic Library Online
(169)
Nature Journals
(154)
Wiley Online Library
(153)
SpringerLink
(152)
Springer Book Series (Lecture Notes)
(128)
JSTOR
(101)
Access via Oxford University Press
(97)
Nexis Uni
(96)
Ebook Central Perpetual and DDA
(89)
eBooks on EBSCOhost
(83)
Oxford Journals 2020 Medicine
(76)

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

The New England Journal Of Medicine
(38)
Nature
(30)
Nature Communications
(26)
Plos One
(26)
New England Journal Of Medicine/the new England Journal Of Medicine
(25)
Physical Review Letters
(25)
The Lancet
(22)
Blood
(20)
Nature Genetics
(20)
The Astrophysical Journal
(20)

5 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 30 Tagen
(1)
... seit 90 Tagen
(17)